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[미국특허] Cell transfection apparatus and method 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-017/36
출원번호 US-0276324 (1994-07-18)
발명자 / 주소
  • Abela George S. (80 Longfellow Rd. Wellesley MA 02181)
인용정보 피인용 횟수 : 51  인용 특허 : 18

초록

An apparatus and associated method provides for the application of a cell treatment agent, such as genetic material or drugs to be inserted within the cells of a patient in vivo. The apparatus may be a catheter arrangement with various embodiments for applying heat to a patient\s cells in vivo in or

대표청구항

An apparatus for cell transfection comprising: an instrument with a housing having a wall with at least one hole therein, wherein said instrument has a distal portion adjacent said hole and a proximal portion remote from said hole; a heater operatively connected to said distal portion so as to apply

이 특허에 인용된 특허 (18) 인용/피인용 타임라인 분석

  1. Cohen Donald (Miami FL), Apparatus for locating and ablating cardiac conduction pathways.
  2. Cremer Christoph (67 Panoramastrasse 6900 Heidelberg DEX) Cremer Thomas (61 Weinbrennerstrasse 6900 Heidelberg DEX) Greulich Karl O. (25-27 Ploeck 6900 Heidelberg DEX) Monajembashi Shamci (5 Rahmenga, Application of cuts to biological material.
  3. Kittrell Carter (Cambridge MA) Cothren ; Jr. Robert M. (Beatrice NE) Feld Michael S. (Waban MA), Catheter for laser angiosurgery.
  4. Abela George S. (80 Longfellow Rd. Wellesley MA 02181), Cell treatment apparatus and method.
  5. Abela George S. (80 Longfellow Rd. Wellesley MA 02181), Cell treatment apparatus and method.
  6. Gruen Dieter M. (Downers Grove IL) Young Charles E. (Westmont IL) Pellin Michael J. (Naperville IL), Excimer laser phototherapy for the dissolution of abnormal growth.
  7. Deckelbaum Lawrence I. (Woodbridge CT), Laser ablation process and apparatus.
  8. Abela George S. (Gainesville FL), Laser apparatus for the recanalization of vessels and the treatment of other cardiac conditions.
  9. Abela George S. (Gainesville FL), Laser method and apparatus for the recanalization of vessels and the treatment of other cardiac conditions.
  10. Abela George S. (Gainesville FL) Friedl Stephan E. (Gainesville FL), Laser treatment apparatus and method.
  11. Laakmann Katherine D. (Seattle WA) Levy Michael B. (Woodinville WA), Lightpipe tip for contact laser surgery.
  12. Hussein Hany M. G. (Costa Mesa CA) Loeb Marvin P. (Huntington Beach CA) Sulek Stanislaw (Huntington Beach CA), Localized heat applying medical device.
  13. Spears J. Richard (Winchester MA) Bourgelais Donna (Malden MA), Method and apparatus for angioplasty.
  14. Alfano Robert R. (Bronx NY), Method and apparatus for detecting the presence of caries in teeth using visible luminescence.
  15. Saadatmanesh Vahid (Irvine CA) Hussein Hany M. G. (Costa Mesa CA) Loeb Marvin P. (Huntington Beach CA) Sulek Stanislaw (Huntington Beach CA) Milburn James A. (Santa Ana CA), Method and apparatus for treating a body site with laterally directed laser radiation.
  16. Kittrell Carter (Cambridge MA) Hayes Gary B. (Leominster MA) Feld Michael S. (Waban MA), Method for making optical shield for a laser catheter.
  17. Lee Benjamin I. (Washington DC), Thermal balloon angioplasty.
  18. Nabel Elizabeth G. (Ann Arbor MI) Nabel Gary J. (Ann Arbor MI), Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor.

이 특허를 인용한 특허 (51) 인용/피인용 타임라인 분석

  1. Davalos, Rafael V.; Rossmeisl, John H.; Garcia, Paulo A., Acute blood-brain barrier disruption using electrical energy based therapy.
  2. Laufer Michael D., Bleb reducer.
  3. Shafirstein, Gal; Ferguson, Scott L.; Waner, Milton, Conductive interstitial thermal therapy device.
  4. Shafirstein, Gal; Ferguson, Scott L.; Waner, Milton, Conductive interstitial thermal therapy device.
  5. Shafirstein,Gal; Ferguson,Scott L.; Waner,Milton, Conductive interstitial thermal therapy device.
  6. Galun, Eithan; Lewis, Aaron; Zeira, Evelyne; Manevitch, Alexandra; Khatchatouriants, Artium; Hemo, Yitzchak, Controlled laser treatment for non-invasive tissue alteration, treatment and diagnostics with minimal collateral damage.
  7. Cantin, Daniel; Cournoyer, Alain; Galarneau, Pierre; Meneghini, Chiara, Device and method for transmitting multiple optically-encoded stimulation signals to multiple cell locations.
  8. Swain, Christopher Paul, Device, system and method for in-vivo cauterization.
  9. Davalos, Rafael V.; Garcia, Paulo A.; Robertson, John L.; Rossmeisl, John H.; Neal, II, Robert E., Electroporation with cooling to treat tissue.
  10. Hammond H. Kirk ; Giordano Frank J. ; Dillmann Wolfgang H., Gene therapies for enhancing cardiac function.
  11. Hammond H. Kirk ; Giordano Frank J. ; Dillmann Wolfgang H., Gene therapies for enhancing cardiac function.
  12. Davalos, Rafael V.; Rossmeisl, John H.; Garcia, Paulo A., Immunotherapeutic methods using irreversible electroporation.
  13. Singh, Errol O., Instrument and method for facilitating endoscopic examination and surgical procedures.
  14. Model, Jeffrey; Rioux, Robert, Integrated pump and generator device and method of use.
  15. Doty, David, Intravascular therapeutic agent delivery.
  16. Pearson, Robert; Ortiz, Mark V.; Callas, Peter, Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD).
  17. Davalos, Rafael V., Irreversible electroporation to create tissue scaffolds.
  18. Sano, Michael B.; Davalos, Rafael V.; Robertson, John L.; Garcia, Paulo A.; Neal, II, Robert E., Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds.
  19. Pruitt ; Sr. J. Crayton, Lighted catheter device and method for use and manufacture thereof.
  20. Wu, Ting, Mechanical transfection devices and methods.
  21. Nau, Jr., William H., Medical devices and methods incorporating frustrated total internal reflection for energy-efficient sealing and cutting of tissue using light energy.
  22. Nau, Jr., William H., Medical devices and methods incorporating frustrated total internal reflection for energy-efficient sealing and cutting of tissue using light energy.
  23. Loftman, Rickard C.; Schlesinger, Randall L.; Jackson, John I.; Garbini, Lex J.; Dull, Douglas B., Medical diagnostic ultrasound catheter with first and second tip portions.
  24. Iezzi, Raymond; Auner, Greg; McAllister, Patrick; Abrams, Gary W., Method and apparatus for activating molecules to stimulate neurological tissue.
  25. Gregory Kenton W., Method for contemporaneous application OF laser energy and localized pharmacologic therapy.
  26. Stevens John H. ; Brewer Richard B. ; Rosenman Daniel C. ; Gifford ; III Hanson S., Method for delivery of therapeutic agents to the heart.
  27. Tachibana Cozier,JPX ; Hansmann Douglas R., Method, device and kit for performing gene therapy.
  28. Brisken, Axel F.; Zuk, Robert; McKenzie, John R.; Cowan, Mark W., Methods and apparatus for uniform transcutaneous therapeutic ultrasound.
  29. Zerfas, Jeffrey W., Methods and apparatus related to a side-fire assembly that has an optical grating.
  30. Zerfas, Jeffrey W., Methods and apparatus related to a side-fire assembly that has an optical grating.
  31. Pearson, Robert, Methods of sterilization and treating infection using irreversible electroporation.
  32. Christopher M. H. Newman GB; Axel F. Brisken, Methods, systems, and kits for intravascular nucleic acid delivery.
  33. Newman, Christopher M. H.; Brisken, Axel F., Methods, systems, and kits for intravascular nucleic acid delivery.
  34. Moss, Kevin L; Pearson, Robert M, Multiple treatment zone ablation probe.
  35. Hoarau, Carine; Podhajsky, Ronald J., Optical hydrology arrays and system and method for monitoring water displacement during treatment of patient tissue.
  36. Negus, Charles Christopher; Linhares, Stephen J.; Rudko, Robert I.; Woodruff, Eileen A.; Andrews, Robert R., Percutaneous myocardial revascularization marking and therapeutic or diagnostic agent delivery system.
  37. Gregory Kenton W., Photoacoustic drug delivery.
  38. Mark R. Schneider ; Christopher D. Conover, Position and orientation measuring with magnetic fields.
  39. Ellis Louis, Radiofrequency transmyocardial revascularization apparatus and method.
  40. Chen James C., Real-time monitoring of photodynamic therapy over an extended time.
  41. Shafirstein, Gal, Selective conductive interstitial thermal therapy device.
  42. Whitebook, Mark Evan; Walker, Blair D.; Evans, Scott M.; Shimada, Lynn M., System and method employing indwelling RF catheter for systemic patient warming by application of dielectric heating.
  43. Neal, II, Robert; Davalos, Rafael V, System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress.
  44. Garcia, Paulo A.; Arena, Christopher B.; Sano, Michael B.; Davalos, Rafael V., System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies.
  45. Callas, Peter; Lovewell, James; Stribling, Bradley C.; Warden, Dave, System and method for synchronizing energy delivery to the cardiac rhythm.
  46. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  47. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  48. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  49. Bennett, Frederick J.; Rodriguey, James E., Ultrasound assembly with increased efficacy.
  50. Bennett, Frederick J.; Zhang, John; Lichttenegger, Gary; Rodriguey, James E.; Tachibana, Katsuro, Ultrasound catheter for providing a therapeutic effect to a vessel of a body.
  51. Wilson, Richard R., Ultrasound radiating members for catheter.

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