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Methods of diagnosing colorectal tumors and metastasis thereof 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/574
  • G01N-033/53
출원번호 US-0305056 (1994-09-13)
발명자 / 주소
  • Waldman Scott A. (Ardmore PA)
출원인 / 주소
  • Thomas Jefferson University (Philadelphia PA 02)
인용정보 피인용 횟수 : 75  인용 특허 : 7

초록

In vitro methods of determining whether or not an individual has metastasized colorectal cancer cells are disclosed. In vitro methods of determining whether or not tumor cells are colorectal in origin are disclosed. In vitro kits for practicing the methods of the invention and to reagents and compos

대표청구항

An in vitro method of determining whether or not an individual has metastasized colorectal cancer cells comprising the steps of examining a sample of extraintestinal tissue and/or body fluids from an individual to determine whether ST receptor protein is being expressed by cells in said sample, wher

이 특허에 인용된 특허 (7)

  1. Ceriani Roberto L. (1089 Via Roble Lafayette CA 94549) Peterson Jerry A. (5916 Chabot Rd. Oakland CA 94618), Method and compositions for carcinoma diagnosis.
  2. Welt Sydney (New York NY) Divgi Chaitanya R. (New York NY) Yeh Samual (New York NY) Old Lloyd J. (New York NY) Oettgen Herbert F. (New Canaan CT) Real Francisco X. (Barcelona ESX) Sakamoto Junichi (C, Method of imaging colorectal carcinoma lesion and composition for use therein.
  3. Innis Michael A. (Moraga CA) Myambo Kenneth B. (Pittsburg CA) Gelfand David H. (Oakland CA) Brow Mary Ann D. (Oakland CA), Methods for DNA sequencing with thermus aquaticus DNA polymerase.
  4. Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
  5. Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Gelfand David H. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme.
  6. Mullis Kary B. (Kensington CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or-cloning nucleic acid sequences.
  7. Garbers David L. (Dallas TX) Schulz Stephanie (Dallas TX), Purified enterotoxin receptor protein.

이 특허를 인용한 특허 (75)

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  5. Shailubhai, Kunwar, Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders.
  6. Shailubhai, Kunwar, Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders.
  7. Shailubhai, Kunwar, Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders.
  8. Shailubhai, Kunwar; Jacob, Gary S., Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders.
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  18. Shailubhai, Kunwar, Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases.
  19. Shailubhai, Kunwar, Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases.
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  22. Frank, Helen Alison; McDonald, Alice A.; O'Keefe, Theresa L., Anti-GCC antibody molecules and methods for use of same.
  23. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  24. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
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  30. Waldman,Scott A.; Park,Jason; Schulz,Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  31. Waldman Scott A., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  32. Waldman Scott A., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
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  37. Waldman,Scott A.; Park,Jason; Schulz,Stephanie, Detection of CDX2 expression.
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  55. Waldman, Scott A.; Magee, Michael S.; Snook, Adam E., Method of treating cancer by administering chimeric antigen receptor comprising anti-GCC antibody.
  56. Waldman, Scott A, Methods of and kits and compositions for diagnosing colorectal tumors.
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  63. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression.
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  65. Waldman, Scott A.; Pearlman, Joshua M.; Barber, Michael T.; Schulz, Stephanie; Parkinson, Scott J.; Prawer, Scott, Methods of using CRCA-1 as a stomach and esophageal cancer marker.
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  75. Waldman, Scott A.; Pitari, Giovanni Mario; Park, Jason; Schulz, Stephanie; Wolfe, Henry R.; Lubbe, Wilhelm, Use of GCC ligands.
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