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특허 상세정보

MyON담기
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Flow cell and method for making same

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) G01N-021/05   
미국특허분류(USC) 356/246 ; 356/440
출원번호 US-0395784 (1995-02-28)
발명자 / 주소
  • Munk Miner N. (Sonoma CA)
출원인 / 주소
  • Thermo Separation Products Inc. (Fremont CA 02)
인용정보 피인용 횟수 : 40  인용 특허 : 16
초록

A coated flow cell and a method for making the coated flow cell are provided. The flow cell comprises a flow passage internally coated with a polymer having an index of refraction lower than that of water. In this manner, light directed into the flow cell is internally reflected or “piped”down the length of the flow passage. As a result, flow cells having path lengths significantly longer and accepting incident angles of light much greater than possible with prior art flow cells. A method for internally coating the flow cell is also provided.

대표
청구항
▼

A flow cell for light absorption measurement comprising: a housing comprising an outer layer of a heat shrinkable polymer and an inner layer of a second polymer, said inner layer of said second polymer forming an interior wall defining a flow passage, said flow passage having an inlet and an outlet through which a liquid phase sample to be analyzed is directed, said housing having a first end and a second end, said first and second ends having transparent windows through which light is directed, and at least a portion of said interior wall having bonded ...

이 특허에 인용된 특허 (16)

  1. Squire Edward N. (Glen Mills PA), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  2. Squire Edward N. (Glen Mills PA), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  3. Squire Edward N. (Glen Mills PA), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  4. Squire Edward N. (Glen Mills PA), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  5. Squire Edward N. (Spring Hill FL), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  6. Squire Edward N. (Spring Hill FL), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  7. Squire Edward N. (Spring Hill FL), Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  8. Liu Su Y. (Sarasota FL), Apparatus and method for measuring light absorption in small aqueous fluid samples.
  9. Allington Robert W. (Lincoln NE) Jones John N. (Lincoln NE), Chromatographic flow cell and method of making it.
  10. Blough ; Jr. William M. (Brea CA), Flow cell.
  11. Shearin Alan (El Toro CA), Fluid catheter with aqueous fluid core and method of use.
  12. Bach David T. (Westborough MA), Liquid/liquid fiber-optic fluorescence detector and absorbance analyzer.
  13. Liu Su Y. (Sarasota FL), Micro chemical analysis employing flow through detectors.
  14. Squire Edward N. (Glen Mills PA), Optical fibers comprising cores clad with amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole.
  15. Gilby Anthony C. (Foxborough MA) Carson William W. (Hopkinton MA), Photometric apparatus with a flow cell coated with an amorphous fluoropolymer.
  16. Bekiarian Paul G. (Claymont DE) Buckmaster Marlin D. (Vienna WV) Morgan Richard A. (Vienna WV), Process for the stabilization of fluoropolymers.

이 특허를 인용한 특허 (40)

  1. Dourdeville Theodore A., Active pump phasing to enhance chromatographic reproducibility.
  2. Martini, Joerg; Kiesel, Peter; Huck, Malte; Bern, Marshall W.; Johnson, Noble M.; Bassler, Michael; Beck, Markus, Analyzers with time variation based on color-coded spatial modulation.
  3. Bahatt,Dar; Kowallis,Reid, Apparatus and method for confining eluted samples in electrophoresis systems.
  4. Munk Miner N., Capillary flow cell with bulbous ends.
  5. Kiesel, Peter; Martini, Joerg, Compact analyzer with spatial modulation and multiple intensity modulated excitation sources.
  6. Bahatt, Dar; Reel, Richard T., Detection cell for guiding excitation light therein and method for using same.
  7. Garrett, Mark H., Fiber-coupled liquid sample analyzer with liquid flow cell.
  8. Hanlon, Gregory; Neal, Timothy; Edwards, Richard; DiCesare, Joseph L.; Aikens, David M., Flow cell assembly for liquid sample analyzer.
  9. Hanlon, Gregory; Neal, Timothy; Edwards, Richard; DiCesare, Joseph L.; Aikens, David M., Flow cell assembly for liquid sample analyzer.
  10. Hanlon, Gregory; Neal, Timothy; Edwards, Richard; DiCesare, Joseph L.; Aikens, David M., Flow cell assembly for liquid sample analyzer.
  11. Hanlon, Gregory; Neal, Timothy; Edwards, Richard, Flow cell modules and liquid sample analyzers and methods including same.
  12. Hanlon, Gregory; Neal, Timothy; Edwards, Richard, Flow cell modules and liquid sample analyzers and methods including same.
  13. Hanlon, Gregory; Neal, Timothy; Edwards, Richard, Flow cell modules and liquid sample analyzers and methods including same.
  14. Dourdeville Theodore A. ; Gilby Anthony C. ; DellaRovere Dennis, Flow cell, analyte measurement apparatus and methods related thereto.
  15. Dourdeville, Theodore A.; Gilby, Anthony C.; DellaRovere, Dennis, Flow cell, analyte measurement apparatus and methods related thereto.
  16. Gerner, Yuri; Sims, Carl W.; Thielen, Thomas, Flow cells utilizing photometric techniques.
  17. Gerner, Yuri; Sims, Carl W.; Thielen, Thomas J., Flow cells utilizing photometric techniques.
  18. Gerner,Yuri; Sims,Carl W.; Thompson,Jonathan, Fluid analysis apparatus.
  19. Gerner,Yuri; Sims,Carl W.; Thompson,Jonathan, Fluid analysis apparatus.
  20. Hanlon, Gregory; Neal, Timothy, Lamp temperature management systems and methods for liquid chromatography analyzers.
  21. Hanlon, Gregory; Neal, Timothy, Lamp temperature management systems and methods for liquid chromatography analyzers.
  22. Gilby, Anthony C., Light-guiding flowcells with minimal stray light.
  23. Dasgupta Purnendu K., Luminescence detector with liquid-core waveguide.
  24. Luscher, Mark, Method and apparatus for limiting effects of refraction in cytometry.
  25. Martino, Anthony Joseph; Schermacher, Ken Stephen; Steenhoek, Larry Eugene; Snyder, Timothy Aaron; Averitt, Robert; Bucher, Jr., Robert E., Method and apparatus for measuring the color properties of fluids.
  26. Bassler, Michael; Kiesel, Peter; Schmidt, Oliver, Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances.
  27. Bassler, Michael; Kiesel, Peter; Schmidt, Oliver; Johnson, Noble M., Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity.
  28. Bassler, Michael; Kiesel, Peter; Schmidt, Oliver; Johnson, Noble M., Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity.
  29. Mueller,Jochen; Mueller,Beno, Method for manufacturing a flow cell.
  30. Luscher, Mark; Marks, Randall, Methods, systems and apparatus for performing flow cytometry.
  31. Cyr,Douglas R.; Farrow,Roger L.; Arnold,Don W., Microfluidic detection device having reduced dispersion and method for making same.
  32. Cyr,Douglas R.; Farrow,Roger L.; Arnold,Don W., Microfluidic detection device having reduced dispersion and method for making same.
  33. Rahbar-Dehghan, Fariborz, Multiple microchannels chip for biomolecule imaging.
  34. Rahbar-Dehghan, Fariborz, Multiple microchannels chip for biomolecule imaging, and method of use thereof.
  35. Gilby, Anthony C., Opaque additive to block stray light in teflon AF light-guiding flowcells.
  36. Kiesel, Peter; Bruce, Richard H.; Bassler, Michael, Particle analyzer with spatial modulation and long lifetime bioprobes.
  37. Belz, Mathias; Liu, Su Yi; Miller, Richard L., Photometric detection system having multiple path length flow cell.
  38. Gerner, Yuri; Sims, Carl W.; Thompson, Jonathan, System for assembling a fluid analysis apparatus.
  39. Jeannotte, Anthony C.; Basile, Mark; Bala, Senthil; Fredette, Colin, Systems and methods for refractive index detection.
  40. Iwase Kenichi,JPX ; Takeuchi Hajime,JPX ; Umehara Yuuki,JPX ; Taguchi Takayuki,JPX ; Fujioka Shigeru,JPX ; Yamaguchi Tadao,JPX, Trace liquid detecting and analyzing device.

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