초록 ▼

The invention relates to a floatable, oral, therapeutic system, in which a lengthening of the gastrointestinal residence time of medicaments and a controlled delivery thereof are achieved by systems, which are specifically lighter than the gastric fluid, float on the latter and can only with difficu

The invention relates to a floatable, oral, therapeutic system, in which a lengthening of the gastrointestinal residence time of medicaments and a controlled delivery thereof are achieved by systems, which are specifically lighter than the gastric fluid, float on the latter and can only with difficulty reach the lower-lying pylorus, said system using at least one structural element with cavities or voids, such as foams or hollow bodies.

대표청구항 ▼

A therapeutic system for the oral administration of a medicament comprising a mixture of particles of the medicament in a therapeutically effective amount and a floatable aid part, wherein the floatable aid is a microporous foam material of a polymer selected from the group consisting of polyethylen

A therapeutic system for the oral administration of a medicament comprising a mixture of particles of the medicament in a therapeutically effective amount and a floatable aid part, wherein the floatable aid is a microporous foam material of a polymer selected from the group consisting of polyethylene, polypropylene, polyamide, polystyrene, polyester, polyacrylate, polytetrafluoroethylene, polyvinylchloride, polyvinylidene chloride, copolymers from the monomers on which said polymers are based and polysiloxane, wherein the floatable aid comprises a microporous foam material having a pore diameter of in the range of between 0.2 and 100 micrometers, wherein the microporous foam material does not contain the medicament within its pores, wherein the system delivers the medicament into gastric juices, and wherein the system floats in the gastric juices.