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Method for producing microcapsule 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
  • A61K-009/52
출원번호 US-0468657 (1995-06-06)
우선권정보 JP-0207760 (1983-11-04)
발명자 / 주소
  • Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX)
출원인 / 주소
  • Takeda Chemical Industries, Ltd. (Osaka JPX 03)
인용정보 피인용 횟수 : 63  인용 특허 : 15

초록 ▼

A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not low

대표청구항 ▼

A method for producing a prolonged release microcapsule for injection, which comprises redispersing a spherical microcapsule having an average diameter of 2 to 200 m100/0 to 50/50and an average molecular weight within the range of about 5,000 to 200,000, in an excipient selected from the group consi

이 특허에 인용된 특허 (15)

  1. Hsiao, Charles H., Aspirin tablet.
    상세보기
  2. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
    상세보기
  3. Taylor ; Jr. Harvey W. (Sayre PA), Element containing lower gloss protective covering and a pre-press color proof.
    상세보기
  4. Kent John S. (Cupertino CA) Lewis Danny H. (Birmingham AL) Sanders Lynda M. (Palo Alto CA) Tice Thomas R. (Birmingham AL), Microencapsulation of water soluble active polypeptides.
    상세보기
  5. Jaffe Howard (Gaithersburg MD), Microencapsulation process.
    상세보기
  6. Tice Thomas R. (Helena AL) Lewis Danny H. (Gardendale AL), Microencapsulation process.
    상세보기
  7. Nestor John J. (San Jose CA) Jones Gordon H. (Cupertino CA) Vickery Brian H. (Cupertino CA), Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone.
    상세보기
  8. Yamamoto Masaki (Osaka JPX) Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Miyagawa Tsutomu (Saitama JPX), Polymer, production and use thereof.
    상세보기
  9. Nevin Robert S. (Indianapolis IN), Polymerization process and product.
    상세보기
  10. Lapka Galen G. (Belleville IL) Mason Norbert S. (Clayton MO) Thies Curt (Ballwin MO), Process for preparation of microcapsules.
    상세보기
  11. Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기
  • Okada Hiroaki (Suita JPX) Ogawa Yasuaki (Ibaraki JPX) Yashiki Takatsuka (Takarazuka JPX), Prolonged release microcapsule and its production.
    상세보기
  • Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX), Prolonged release microcapsules and their production.
    상세보기
  • Yamamoto Masaki (Osaka JPX) Takada Shigeyuki (Osaka JPX) Ogawa Yasuaki (Osaka JPX), Sustained release microcapsule.
    상세보기
  • Rotman Avner (6 Alkalai Street Rehovot ILX), Sustained release tablets made from microcapsules.
    상세보기

    • 이 특허를 인용한 특허 (63)

    1. Palmer, Daniel; Shadick, Owen, Apparatus and method for making solid beads.
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    2. Dunn, Richard L; English, James P., Biodegradable polymer composition.
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    3. Richard L Dunn ; James P. English, Biodegradable polymer composition.
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    4. Thanoo Bagavathikanun Chithambara ; Murtagh James, Continuous microsphere process.
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    5. Cheng, Xiu Xiu; Jan, Steve; Chou, Joseph; Chen, Chih-Ming, Controlled release metformin formulations.
      상세보기
    6. Xiu Xiu Cheng ; Chih-Ming Chen ; Steve Jan ; Joseph Chou, Controlled release oral tablet having a unitary core.
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    7. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakis, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
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    8. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakls, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
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    9. Dalton, James T.; Herring, Christina; Miller, Duane D.; Hong, Seoung-Soo; He, Yali; Mohler, Michael L.; Narayanan, Ramesh; Wu, Zhongzhi, Estrogen receptor ligands and methods of use thereof.
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    10. Dalton, James T.; Steiner, Mitchell S.; Coss, Christopher C.; Getzenberg, Robert H., Estrogen receptor ligands and methods of use thereof.
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    11. Dalton, James T.; Steiner, Mitchell S.; Eswaraka, Jeetendra, Estrogen receptor ligands and methods of use thereof.
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    12. Dalton, James T.; Steiner, Mitchell S.; Eswaraka, Jeetendra, Estrogen receptor ligands and methods of use thereof.
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    13. Dalton, James T.; Steiner, Mitchell S.; Morton, Ronald A., Estrogen receptor ligands and methods of use thereof.
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    14. Albayrak,Celal, Induced phase transition method for the production of microparticles containing hydrophilic active agents.
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    15. Albayrak, Celal, Induced phase transition method for the production of microparticles containing hydrophobic active agents.
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    16. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D., Macromolecular microparticles and methods of production and use.
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    17. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
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    18. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
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    19. Bagavathikanun Chithambara Thanoo ; James Murtagh, Method and apparatus for formulating microspheres and microcapsules.
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    20. Thanoo Bagavathikanun Chithambara ; Murtagh James, Method and apparatus for formulating microspheres and microcapsules.
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    21. Palmer, Daniel; Shadick, Owen, Method for making solid beads.
      상세보기
    22. Soper Jon C. ; Kim Young D. ; Thomas Margaret T., Method of encapsulating flavors and fragrances by controlled water transport into microcapsules.
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    23. Soper Jon C. ; Yang Xiaogen ; Josephson David B., Method of encapsulating flavors and fragrances by controlled water transport into microcapsules.
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    24. Brown, Larry; McGeehan, John K.; Rashba-Step, Julia; Scott, Terrence L., Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation.
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    25. Darvari, Ramin; Lambert, Adam; Rashba-Step, Julia E.; Yang, Mark X.; Zhang, Junhong; O'Connell, Ed, Methods of processing compositions containing microparticles.
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    26. Piran, Uri; Mehr, Eugene; Brown, Larry R.; McGeehan, John K.; O'Connell, Ed, Methods of processing compositions containing microparticles.
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    27. Piran, Uri, Methods of processing multi-phasic dispersions.
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    28. Lee, Ronald D.; Vakily, Majid; Mulford, Darcy; Wu, Jing-Tao; Atkinson, Stuart, Methods of treating gastrointestinal disorders independent of the intake of food.
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    29. Brown, Larry R.; Giannoukakis, Nick; Gillis, Kimberly A.; Trucco, Massimo, Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
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    30. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
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    31. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
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    32. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
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    33. Dalton, James T.; Barrett, Christina; Miller, Duane D.; Hong, Seoung-Soo; He, Yali; Mohler, Michael L.; Narayanan, Ramesh; Wu, Zhongzhi, Nuclear receptor binding agents.
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    34. Brown, Larry R.; Scott, Terrence L.; Lafreniere, Debra; Bisker-Leib, Vered, Nucleic acid microspheres, production and delivery thereof.
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    35. Scott, Terrence; Lafreniere, Debra; Bisker-Leib, Vered; Brown, Larry, Nucleic acid microspheres, production and delivery thereof.
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    36. Yano, Tetsuya; Nomoto, Tsuyoshi; Kozaki, Shinya; Imamura, Takeshi; Honma, Tsutomu, Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof.
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    37. Dunn, Richard L.; Garrett, John Steven; Ravivarapu, Harish; Chandrashekar, Bhagya L., Polymeric delivery formulations of leuprolide with improved efficacy.
      상세보기
    38. Rossling, Georg; Albayrak, Celal; Tack, Johannes; Schmitz, Reinhard, Process for the production of morphologically uniform microcapsules and microcapsules that are produced according to this process.
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    39. Lee, Hee-Yong; Kim, Jung-Soo; Shin, Eun-Ho; Kim, Seong-Kyu; Seol, Eun-Young; Baek, Mi-Jin; Baek, Mi-Young; Chae, Yeon-Jin; Choi, Ho-Il; Lee, Juhan, Process of preparing microspheres for sustained release having improved dispersibility and syringeability.
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    40. Brown,Larry R., Production of microspheres.
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    41. Brown, Larry; Bisker-Leib, Vered; LaFreniere, Debra; McGeehan, John; Rashba-Step, Julia; Scott, Terrence, Protein microspheres having injectable properties at high concentrations.
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    42. Brown, Larry R.; Yang, Mark X.; O'Connell, Ed, Protein microspheres retaining pharmacokinetic and pharmacodynamic properties.
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    43. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Duke, Charles B.; Coss, Christopher C.; Jones, Amanda; Dalton, James T., Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    44. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Duke, Charles B.; Coss, Christopher C.; Jones, Amanda; Dalton, James T., Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    45. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Duke, Charles B.; Coss, Christopher C.; Jones, Amanda; Dalton, James T., Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    46. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Pagadala, Jayaprakash; Duke, Charles B.; Coss, Christopher C.; Dalton, James T.; He, Yali, Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    47. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Pagadala, Jayaprakash; Duke, Charles B.; Coss, Christopher C.; Dalton, James T.; He, Yali, Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    48. Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; Pagadala, Jayaprakash; Duke, Charles B.; Coss, Christopher C.; Dalton, James T.; He, Yali, Selective androgen receptor degrader (SARD) ligands and methods of use thereof.
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    49. Dadey, Eric; Zhou, Mingxing, Stabilized polymeric delivery system comprising a water-insoluble polymer and an organic liquid.
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    50. Margaron, Philippe Maria Clotaire; Dadey, Eric; Lindemann, Christopher M.; Li, Ruihong, Sustained delivery formulations of rapamycin compounds.
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