IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0464277
(1995-06-05)
|
발명자
/ 주소 |
- Kurtz Robert J. (New York NY) Fuller William D. (San Diego CA)
|
출원인 / 주소 |
- Bioresearch, Inc. (Arlington VA 02)
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인용정보 |
피인용 횟수 :
16 인용 특허 :
18 |
초록
Ingestible compounds which are substantially tasteless and which have been found to be effective reducers or eliminators of undesirable tastes for eatables.
대표청구항
▼
A composition comprising an eatable having at least one taste selected from bitter and metallic, and at least one tastand in a substantially tasteless amount of about 0.0000001 to about 300% by weight, based on the weight of the eatable, which amount is sufficient to reduce said at least one bitter
A composition comprising an eatable having at least one taste selected from bitter and metallic, and at least one tastand in a substantially tasteless amount of about 0.0000001 to about 300% by weight, based on the weight of the eatable, which amount is sufficient to reduce said at least one bitter and metallic taste, said tastand being selected from the group consisting of compounds which are substantially tasteless in the amount used and have the structure: [Figure] I-1 wherein p and q are independently selected from the group consisting of 1, 2, 3, 4 or 5; each R1 and R2, which may be the same or different, are independently selected from the group consisting of H, hydroxy, nitro, cyano, halogen, COOH, SO3H, CH2SO2NH2, trifluoroacetyl, an acid group of the structure ZOqHr wherein Z is an element selected from the group consisting of carbon, sulfur, boron or phosphorus, q is an integer from 2 to 3 and r is an integer from 1 to 3; and an O, S, N or phosphorylated glycoside, where the glycoside is selected from the group consisting of monosaccharides, disaccharides, trisaccharides, and oligosaccharides all of which saccharides may be substituted; and the following groups which may be substituted or unsubstituted: amino, alkyl, alkoxy, aryl, alkylene, aminoacyl, aryloxy, aralkoxy, acyl, arylacyl, benzoyl, alkylamino, dialkylamino, trialkylamino, carbonates, alkylcarbonates, arylcarbonates, acylamino, guanidino, alkylguanidino, acylguanidino, arylguanidino, alkylurethanes, arylurethanes, ureas, alkylureas, CHO, COCH3, COCH3, CH2CHO, CH2COOH, COOCH3, OCOCH3, CONH2, NHCHO, SCH3, SCH2CH3, CH2SCH3, SO2NH2, SO2CH3, CH2SO3H, cycloalkyl, heterocyclic, polycyclic, arylureas, carboxylic acid ester, carboxamide, N-alkyl carboxamide, di-alkyl carboxamides, and wherein any two substituents taken together can be an aliphatic chain linked to a phenyl ring at one or more positions either directly via a carbon atom or indirectly via an oxygen, nitrogen or sulfur atom to form a ring structure; and each of R3 and R4, R5, R6, which may be the same or different, are independently selected from the group consisting of H, trifluoromethyl, halogen, cyano; and substituted or unsubstituted alkyl, alkylene, branched alkyl, branched alkylene, aryl, aralkyl, cycloalkyl, acyl, benzoyl, alkoxy, aryloxy, heterocyclic, polycyclic; where CH-CH or CH2-CH2 bonds exist the level of unsaturation may be increased by removing one or more hydrogen atoms from the carbon atoms participating in the CH-CH or CH2-CH2 bonds, and physiologically acceptable salts or all of the foregoing.
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