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Taste-masking composition of bitter pharmaceutical agents 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
  • A61K-047/02
출원번호 US-0328977 (1994-10-24)
발명자 / 주소
  • Catania Joseph S. (Gales Ferry CT) Johnson Alton D. (Groton CT)
출원인 / 주소
  • Pfizer Inc. (New York NY 02)
인용정보 피인용 횟수 : 51  인용 특허 : 5

초록

A pharmaceutical composition having reduced bitterness consisting of a bitter pharmaceutical agent, a taste-masking component and a pharmaceutically acceptable carrier. The taste-masking component is an alkaline earth oxide, an alkaline earth hydroxide or an alkaline hydroxide and does not interfere

대표청구항

A chewable tablet or liquid suspension pharmaceutical composition having reduced bitterness comprising azithromycin, an alkaline earth oxide and a pharmaceutically acceptable carrier.

이 특허에 인용된 특허 (5)

  1. Kobrehel Gabrijela (Zagreb YUX) Djokic Slobodan (Zagreb YUX), 11-Methyl-11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane.
  2. Gergely Gerhard (Gartengasse 8 A1050 Wein ATX) Gergely Thomas (Gartengasse 8 A1050 Wein ATX) Gergely Irmgard (Gartengasse 8 A1050 Wein ATX), Effervescent composition and method of making same.
  3. Denick ; Jr. John (Newton NJ) Peters David (Long Valley NJ) Talwar Anil K. (Long Valley NJ) Liao Wei C. (Iselin NJ), Medicament adsorbates of analgesics with complex magnesium aluminum silicate and their preparation.
  4. Bright Gene M. (Groton CT), N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor.
  5. Mehta Atul M. (252 E. Crescent Ave. Ramsey NJ 07446), Taste-masked pharmaceutical compositions.

이 특허를 인용한 특허 (51)

  1. Keller, Manfred; Schuschnig, Uwe; Zimmermann, Johann; Luber, Martin; Böhm, Andreas, Aerosols for sinunasal drug delivery.
  2. Keller, Manfred; Schuschnig, Uwe; Zimmermann, Johann; Luber, Martin; Böhm, Andreas, Aerosols for sinunasal drug delivery.
  3. Nandi, Indranil; Guo, Mintong; Gassert, Chad Michael; Schwarz, Franz Xaver; Kosilek, Irina, Antibiotic clarithromycin micropellet compositions.
  4. Rudnic,Edward M., Antibiotic composition with inhibitor.
  5. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  6. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  7. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  8. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  9. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  10. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  11. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  12. Rudnic, Edward M.; Isbister, James D.; Treacy, Jr., Donald J.; Wassink, Sandra E., Antifungal once-a-day product, use and formulation thereof.
  13. Rudnic,Edward M.; Isbister,James D.; Treacy, Jr.,Donald J.; Wassink,Sandra E., Antiviral product, use and formulation thereof.
  14. Hagen,Timothy A.; Lo,Julian B.; Thombre,Avinash G.; Herbig,Scott M.; Appel,Leah Elizabeth; Crew,Marshall David; Friesen,Dwayne Thomas; Lyon,David Keith; McCray,Scott Baldwin; West,James Blair, Azithromycin dosage forms with reduced side effects.
  15. Flanner, Henry H.; Guttendorf, Robert J.; Clausen, Susan P.; Treacy, Donald; Burnside, Beth A., Compositions and methods for improved efficacy of penicillin-type antibiotics.
  16. Dang, Phuong Grace; Lawrence, Brian D.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine.
  17. Dang, Phuong Grace; Lawrence, Brian D.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine and methods of use thereof.
  18. Prakash, Indra; DuBois, Grant E., Condiments with high-potency sweetener.
  19. Shiomi, Takuya; Okuhara, Yasuhide; Tamura, Akiko; Tomita, Kyoko; Shigematsu, Norihiro; Kikuchi, Hiroto; Aritsuka, Tsutomu; Tomita, Fusao, Difructose anhydride-containing composition and use thereof.
  20. Murphy,Brendan; Collier,Steven W.; Quan,Ernest; Johnson,Barbara A., Directly compressible formulations of azithromycin.
  21. Johnson,Barbara A.; Quan,Ernest S., Dry granulated formulations of azithromycin.
  22. Notario, Gerard F.; Palmer, Robert N.; Hom, Richard C.; Zhang, Jie; Devcich, Karen J.; Semla, Susan J., Extended release formulations of erythromycin derivatives.
  23. Notario, Gerard F.; Palmer, Robert N.; Hom, Richard C.; Zhang, Jie; Devcich, Karen J.; Semla, Susan J., Extended release formulations of erythromycin derivatives.
  24. Ray, Roderick J.; Appel, Leah E.; Newbold, David D.; Friesen, Dwayne T.; McCray, Scott B.; Lyon, David K.; West, James B.; Crew, Marshall D.; Shockey, Joshua R., Extrusion process for forming chemically stable drug multiparticulates.
  25. Jeong, Hyun Jun; Chang, Ik Hyeon; Kim, Dal Geun; Lee, Jin Hoo; Um, Jin Hee; Kim, Hyun Soo; Jung, Kyung Tae; Yeon, Kyu Jeong; Park, Jin Gyu, High-content fast dissolving film with masking of bitter taste comprising sildenafil as active ingredient.
  26. Prakash, Indra; DuBois, Grant E., High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith.
  27. Nakamura, Taiju; Abe, Taichi; Miyashita, Yusuke; Kuroda, Hirofumi; Ayata, Yusuke; Akao, Atsushi, High-purity quinoline derivative and method for manufacturing same.
  28. Curatolo,William J.; Foulds,George H.; Friedman,Hylar L., Method of administering azithromycin.
  29. Flanner, Henry H.; Tolle-Sander, Sanna; Treacy, Donald; Burnside, Beth A.; Clausen, Susan P., Modified release amoxicillin products.
  30. Appel, Leah E.; Ray, Roderick J.; Lyon, David K.; West, James B.; McCray, Scott B.; Crew, Marshall D.; Friesen, Dwayne T.; Herbig, Scott M.; Lo, Julian B., Multiparticulate crystalline drug compositions having controlled release profiles.
  31. Rudnic, Edward M; Isbister, James D; Treacy, Jr., Donald J; Wassink, Sandra E, Once a day amoxicillin product comprising immediate and delayed release dosage forms.
  32. Pereira, David E.; Wu, Sara; Fernandes, Prabhavathi, Parenteral formulations for administering macrolide antibiotics.
  33. Weibel, Ludwig Daniel; Philipp, Erik, Pharmaceutical compositions.
  34. Flanner, Henry H.; Guttendorf, Robert; Treacy, Donald; Clausen, Susan P.; Burnside, Beth A., Pharmaceutical compositions and methods for improved bacterial eradication.
  35. Yang, Robert K.; Fuiz, Richard C.; Myers, Garry L.; Fuiz, Joseph M., Process for making a film having a substantially uniform distribution of components.
  36. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Process for manufacturing a resulting multi-layer pharmaceutical film.
  37. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Process for manufacturing a resulting multi-layer pharmaceutical film.
  38. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Process for manufacturing a resulting pharmaceutical film.
  39. Pereira, David Eugene; Patel, Manish K.; Deo, Keshav, Process for the preparation of macrolide antibacterial agents.
  40. Cao, Bruce X.; Burnside, Beth A.; Wassink, Sandra E.; Baker, Matt R., Robust pellet.
  41. Dunne,Michael W., Single dose azithromycin.
  42. Dunne,Michael William, Single dose azithromycin.
  43. Schobel, Alexander M; Vangala, Shyam S, Solid dosage form containing a taste masked active agent.
  44. Cao, Bruce; Wassink, Sandra E.; Treacy, Jr., Donald J.; Burnside, Beth A.; Rowlings, Colin E.; Bonck, John A., Tablet for pulsed delivery.
  45. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom.
  46. Allen Douglas J. M. ; Arenson Daniel R. ; Sekulic S. Sonja, Trovafloxacin oral suspensions.
  47. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Uniform films for rapid dissolve dosage form incorporating taste-masking compositions.
  48. Yang, Robert K.; Fuisz, Richard C.; Myers, Garry L.; Fuisz, Joseph M., Uniform films for rapid dissolve dosage form incorporating taste-masking compositions.
  49. Myers, Garry L.; Sanghvi, Pradeep; Verrall, Andrew Philip; Francis, Vimala; Brooks, Laura, Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions.
  50. Myers, Garry L.; Sanghvi, Pradeep; Verrall, Andrew Philip; Francis, Vimala; Moss, Laura, Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions.
  51. Shiomi, Takuya; Okuhara, Yasuhide; Tamura, Akiko; Tomita, Kyoko; Shigematsu, Norihiro; Kikuchi, Hiroto; Aritsuka, Tsutomu; Tomita, Fusao, Use of difructose anhydride-containing composition.
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