초록 ▼

The invention covers a method of implanting a living donor cell into a host animal without inflammatory response or rejection of the donor cell by the host animal, by obtaining an uncoated particle of a biocompatible, temperature-independent gel that encapsulates the living donor cell, wherein the u

The invention covers a method of implanting a living donor cell into a host animal without inflammatory response or rejection of the donor cell by the host animal, by obtaining an uncoated particle of a biocompatible, temperature-independent gel that encapsulates the living donor cell, wherein the uncoated particle provides a molecular weight cutoff that prevents host animal immune cells from entering the particle, yet does not have to prevent entry of host animal IgG and complement into the particle, and implanting the uncoated particle into the host animal.

대표청구항 ▼

A method of implanting a living donor cell into a host animal, wherein said animal is a mammal larger than a rat or mouse, with minimal inflammatory response or rejection of the donor cell by the host animal, said method comprising the steps of obtaining an uncoated particle consisting essentially o

A method of implanting a living donor cell into a host animal, wherein said animal is a mammal larger than a rat or mouse, with minimal inflammatory response or rejection of the donor cell by the host animal, said method comprising the steps of obtaining an uncoated particle consisting essentially of a biocompatible, temperature-independent gel that encapsulates the living donor cell, wherein said uncoated particle provides a molecular weight cutoff that prevents host animal immune cells from entering the particle, and does not prevent entry of host animal IgG and complement into said particle, wherein said particle has a diameter of 700-6,000 microns, and implanting the uncoated particle into the host animal.