[특허]Particle aggregation method and apparatus

[미국특허] Particle aggregation method and apparatus 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	G01N-033/557 G01N-001/18
출원번호	US-0302658 (1994-09-08)
우선권정보	GB-0005128 (1992-03-10)
국제출원번호	PCT/GB93/00504 (1993-03-10)
§371/§102 date	19940908 (19940908)
국제공개번호	WO-9319367 (1993-09-30)
발명자 / 주소	Coakley William Terence (Cardiff GBX) Grundy Martin Alan (Pembroke Dock GBX) Bolex Werner (Vienna ATX)
출원인 / 주소	University College Cardiff Consultants Limited (GBX 03)
인용정보	피인용 횟수 : 18 인용 특허 : 0

초록 ▼

A sample of liquid with suspended particles is contained in a tube and subjected to a standing wave ultrasound field transverse to the tube, the standing wave exhibiting a progressive change in pressure amplitude transverse to the tube, so that particles in suspension are displaced transversely of the tube to one or more predetermined regions; exposure of the sample to the standing wave is then terminated and the particles are allowed to settle, and inspected to determine whether they remain aggregated or whether they dissociate. The ultrasound field is produced by a transducer of tubular form encircling the tube. The invention may be used for agglutination of particles or cells via cross-bridging molecules in immuno-agglutination assays.

대표청구항 ▼

A method of carrying out an immuno-agglutination assay, the method comprising: providing a sample of liquid in which particles potentially susceptible to agglutination are suspended; containing said sample within a tube in a manner producing an upper and a lower boundary on said liquid sample within the tube, said lower boundary forming a meniscus onto which said particles are allowed to settle; placing said tube such that it is encircled by a tubular ultrasound transducer; exciting said tubular ultrasound transducer to generate a standing wave ultrasound field within said tube, said standing wave field extending radially of said tube and exhibiting a progressive change in pressure amplitude radially within said tube so that particles suspended in said liquid sample are displaced radially of said tube to aggregate at least one predetermined annular region; terminating the exposure of said liquid sample to said standing wave and allowing said particles to settle; and inspecting said particles whilst said particles are settling to determine whether they remain aggregated together or whether they disperse.

이 특허를 인용한 특허 (18) 인용/피인용 타임라인 분석

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Katou, Hajime; Miyake, Ryo; Uchida, Hiroyasu; Kambara, Katsuhiro; Okusa, Takenori; Watari, Shigenori; Suzuki, Yoichiro; Mimura, Tomonori; Taki, Miki; Inagaki, Akira, Chemical analysis apparatus and chemical analysis method.
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Katou, Hajime; Miyake, Ryo; Uchida, Hiroyasu; Kambara, Katsuhiro; Okusa, Takenori; Watari, Shigenori; Suzuki, Yoichiro; Mimura, Tomonori; Taki, Miki; Inagaki, Akira, Chemical analysis apparatus and chemical analysis method.
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Katou, Hajime; Miyake, Ryo; Uchida, Hiroyasu; Kambara, Katsuhiro; Okusa, Takenori; Watari, Shigenori; Suzuki, Yoichiro; Mimura, Tomonori; Taki, Miki; Inagaki, Akira, Chemical analysis apparatus and chemical analysis method.
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Yu, Liping; Warner, Brian David; Trotter, Joseph T., Devices and methods for manipulating components in a fluid sample.
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Yu, Liping; Warner, Brian David; Trotter, Joseph T., Devices and methods for manipulating components in a fluid sample.
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Yu, Liping; Warner, Brian David; Trotter, Joseph T., Devices and methods for manipulating components in a fluid sample.
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Yu, Liping, Devices and methods for separating magnetically labeled moieties in a sample.
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Mori Kiyoshi, Identifying causes of semiconductor production yield loss.
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Lal,Amit; Lee,Chung Hoon, Method and apparatus for separating particles by size.
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Bystryak, Simon; Ossina, Natalya; Sarvazyan, Armen P., Method and device for ultrasound assisted particle agglutination assay.
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Hoyos, Mauricio; Castro Camacho, Luz Angélica, Method of manipulating objects.
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Coakley William Terence,GBX ; Grundy Martin Alan,GBX ; Bolek Werner,ATX, Particle aggregation method and apparatus.
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Custodero, Emmanuel; Simonot, Laure; Tardivat, Jean-Claude, Reinforcing aluminum-based filler and rubber composition comprising such a filler.
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Custodero,Emmanuel; Simonot,Laure; Tardivat,Jean Claude, Reinforcing aluminum-based filler and rubber composition comprising such a filler.
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Custodero, Emmanuel; Simonot, Laure; Tardivat, Jean-Claude, Reinforcing aluminum-based filler and rubber composition comprising such a filter.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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[미국특허] Particle aggregation method and apparatus 원문보기