초록 ▼

The invention discloses methods for preserving organs in brain-dead humans or cadavers which allows additional time for the organs to remain viable such that they may be harvested for subsequent transplantation. This invention also discloses methods for preserving and/or resuscitating organs in live

The invention discloses methods for preserving organs in brain-dead humans or cadavers which allows additional time for the organs to remain viable such that they may be harvested for subsequent transplantation. This invention also discloses methods for preserving and/or resuscitating organs in live (nonbrain-dead) patients, allowing for additional time to stabilize the patient's condition. The methods include the steps of instrumentizing (e.g., catheterizing, cannulating, injecting, etc.) the vessels or tissues around the organ, or the organ itself sought to be preserved and/or resuscitated, the body cavity, or cavities of the body, and introducing a temperature-controlled solution to preserve and/or resuscitate the organ(s). The temperature-controlled organ preservation solution includes components such as oxygen carrying agents, antioxidants, tissue damage reversing and protecting agents, carrier vehicles, diluents, nutrients, and anti-coagulating agents. A device which performs this method is also disclosed. This device includes a fluid reservoir, an oxygen tank, a heat exchanger and removable catheter lines.

대표청구항 ▼

[ What is claimed is:] [1.] An apparatus for cooling living tissue in a mammalian body, comprising at least one reservoir containing an intravenously biocompatible solution within said at least one reservoir and said at least one reservoir having a solution outlet and an oxygen inlet separate from s

[ What is claimed is:] [1.] An apparatus for cooling living tissue in a mammalian body, comprising at least one reservoir containing an intravenously biocompatible solution within said at least one reservoir and said at least one reservoir having a solution outlet and an oxygen inlet separate from said solution outlet for delivery of oxygen to said at least one reservoir; a chiller in heat exchange communication with said at least one reservoir; a fluid flow system in communication with said solution outlet, and means in communication with said fluid flow system for delivering said intravenously biocompatible solution to tissues and/or organs in said mammalian body.