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[미국특허] Photoactivatable chemiluminescent matrices 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/52
  • C12Q-001/68
  • C12Q-001/00
  • C09K-011/00
출원번호 US-0470862 (1995-06-06)
발명자 / 주소
  • Pease John S.
  • Kirakossian Hrair
  • Wagner Daniel B.
  • Ullman Edwin F.
출원인 / 주소
  • Syntex (U.S.A.) Inc.
대리인 / 주소
    Finnegan, Henderson, Farabow, Garrett & Dunner
인용정보 피인용 횟수 : 94  인용 특허 : 37

초록

Methods for labeling a material are disclosed. The methods comprise combining with the material (a) a photosensitizer capable upon irradiation of generating singlet oxygen and (b) a chemiluminescent compound capable of being activated by singlet oxygen wherein the photosensitizer and the chemilumine

대표청구항

[ What is claimed is:] [1.] A method for determining the presence or absence of an analyte, said method comprising:irradiating a composition suspected of containing the analyte, said composition comprising a non-particulate solid matrix or a particulate matrix, said matrix having incorporated therei

이 특허에 인용된 특허 (37) 인용/피인용 타임라인 분석

  1. Buckler Robert T. (Edwardsburg MI) Schroeder Hartmut R. (Elkhart IN), Amino-functionalized phthalhydrazides.
  2. McCapra Frank (Seaford GB3), Assays utilizing sensitizer-induced production of detectable signals.
  3. Maggio Edward T. (Redwood City CA), Chemically induced fluorescence immunoassay.
  4. Schaap Arthur P. (Detroit MI), Chemiluminescent 1,2-dioxetane compounds.
  5. Schaap Arthur P. (Detroit MI), Chemiluminescent 1,2-dioxetane compounds.
  6. Liu Yen-Ping (Santa Clara CA) Ullman Edwin F. (Atherton CA) Becker Martin J. (Palo Alto CA), Energy absorbing particle quenching in light emitting competitive protein binding assays.
  7. Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA), Fluorescence quenching with immunological pairs in immunoassays.
  8. Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA), Fluorescence quenching with immunological pairs in immunoassays.
  9. Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA), Fluorescence quenching with immunological pairs in immunoassays.
  10. Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Sunnyvale CA), Fluorescence quenching with immunological pairs in immunoassays.
  11. Zuk Robert F. (Menlo Park CA) Litman David J. (Mountain View CA), Fluorescent microbead quenching assay.
  12. Yaverbaum Sidney (East Windsor NJ) Kusnetz Jacob (New City NY), Fluoroimmunoassaying.
  13. Allen Robert C. (Little Rock AR), Haloperoxidase acid optimum chemiluminescence assay system.
  14. Boguslaski, Robert C.; Carrico, Robert J.; Christner, James E., Heterogenous chemiluminescent specific binding assay.
  15. Wagner Daniel B. (Raleigh NC), Homogeneous chemiluminescence immunoassay using a light absorbing material.
  16. Boguslaski, Robert C.; Carrico, Robert J., Homogeneous chemiluminescent specific binding assay.
  17. Cole Francis X. (Stow MA), Immunoassay with antigen or antibody labeled liposomes sequestering enzyme.
  18. Maggio Edward T. (Redwood City CA), Kit for carrying out chemically induced fluorescence immunoassay.
  19. Ullman Edwin F. (Atherton CA) Brinkley John M. (Oakland CA), Labeled liposome particle compositions and immunoassays therewith.
  20. Fountain Michael W. (Plainsboro NJ) Weiss Steven J. (Heightstown NJ) Popescu Mircea C. (Plainsboro NJ), Lipid vesicles prepared in a monophase.
  21. Szoka Frank C. (San Francisco CA), Liposomes with glycolipid-linked antibodies.
  22. Litman David J. (Cupertino CA) Harel Zvi (Haifa CA ILX) Ullman Edwin F. (Atherton CA), Macromolecular fluorescent quencher particle in specific receptor assays.
  23. Schaap Arthur P. (Detroit MI), Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes.
  24. Hunt C. Anthony (San Francisco CA) Papahadjopoulous Demetrios P. (Lafayette CA), Method for producing liposomes in selected size range.
  25. Bronstein Irena Y. (Newton MA), Method of detecting a substance using enzymatically-induced decomposition of dioxetanes.
  26. Mezei Michael (Halifax CAX) Nugent Fredric J. (Halifax CAX), Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV).
  27. Birks John W. (Boulder CO) Shellum Curtis L. (Boulder CO), Method of improving the detection limits of UV-VIS absorbing compounds in HPLC by the use of a singlet oxygen trap.
  28. Jolley Michael E. (Round Lake IL), Method of solid phase immunoassay incorporating a luminescent label.
  29. Bronstein Irena Y. (Newton MA) Voyta John C. (North Reading MA), Methods of using chemiluminescent 1,2-dioxetanes.
  30. Pease John (Los Altos CA) Weng Litai (Mountain View CA) Kirakossian Hrair (San Jose CA) Ullman Edwin F. (Atherton CA), Particle with luminescer for assays.
  31. Neckers Douglas C. (Bowling Green OH) Blossey Erich C. (Winter Park FL) Schaap A. Paul (Detroit MI), Polymer-bound photosensitizing catalysts.
  32. Litman David J. (Palo Alto CA) Ullman Edwin F. (Atherton CA), Preferential signal production on a surface in immunoassays.
  33. Evans John R. (Macclesfield GB2) Fildes Francis J. T. (Macclesfield GB2) Oliver Jean E. (Macclesfield GB2), Process for preparing freeze-dried liposome compositions.
  34. Dattagupta Nanibhushan (New Haven CT), Prolonged enhanced chemiluminescence.
  35. Maggio Edward T. (Redwood City CA) Wife Richard L. (Sittingbourne CA GB2) Ullman Edwin F. (Atherton CA), Reagents and method employing channeling.
  36. Lenk Robert P. (Lambertville NJ) Fountain Michael W. (Plainsboro NJ) Janoff Andrew S. (Lawrenceville NJ) Ostro Marc J. (North Brunswick NJ) Popescu Micrea C. (Plainsboro NJ), Stable plurilamellar vesicles, their preparation and use.
  37. Bronstein Irena Y. (Newtown MA) Edwards Brooks (Cambridge MA), Synthesis of 1,2-dioxetanes.

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  41. Swager, Timothy M.; Thomas, III, Samuel W., Luminescent detection of hydrazine and hydrazine derivatives.
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  44. Pidaparthi,Sailaja; Shi,Yining; Dua,Rajiv; Chan Hui,Po Ying; Singh,Sharat, Measuring receptor homodimerization.
  45. Sharat Singh ; Edwin F. Ullman, Metal chelate containing compositions for use in chemiluminescent assays.
  46. Singh Sharat ; Ullman Edwin F., Metal chelate containing compositions for use in chemiluminescent assays.
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  50. Ehud Ben-Hur ; Maria M. Zuk ; Wai-Shun Chan, Method and composition for hair removal.
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  60. Kurn, Nurith, Methods and compositions for transcription-based nucleic acid amplification.
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