초록 ▼

The invention relates to a combination of substances (component I) inducing necrosis in tumors or inflamed tissue with other nontoxic substances ("prodrugs", component II). The enzymes set free by necrotic processes then cleave the nontoxic "prodrug" into the toxic "drug", which leads to massive tum

The invention relates to a combination of substances (component I) inducing necrosis in tumors or inflamed tissue with other nontoxic substances ("prodrugs", component II). The enzymes set free by necrotic processes then cleave the nontoxic "prodrug" into the toxic "drug", which leads to massive tumor cell death and/or remission of inflammation.

대표청구항 ▼

[ We claim:] [1.] A pharmaceutical composition for use in cytostatic or immunotherapy, comprising a component I and a component II, wherein said component I comprises at least one compound that produces necroses a in tumor or in an inflammatory process, said necroses resulting in the release of at l

[ We claim:] [1.] A pharmaceutical composition for use in cytostatic or immunotherapy, comprising a component I and a component II, wherein said component I comprises at least one compound that produces necroses a in tumor or in an inflammatory process, said necroses resulting in the release of at least one enzyme, and component II comprises one or more compounds that are converted by said at least one enzyme released by said necroses into a cytotoxic drug.