초록 ▼

A medical device which is a surgically implantable device coated with an adjunctive polymer system. The adjunctive polymer system forms a solid matrix when introduced into a human or animal body. The adjunctive polymer system can contain a drug or a medicament which is released over time from the so

A medical device which is a surgically implantable device coated with an adjunctive polymer system. The adjunctive polymer system forms a solid matrix when introduced into a human or animal body. The adjunctive polymer system can contain a drug or a medicament which is released over time from the solid matrix. The adjunctive polymer system contacts body tissue into which the surgically implantable device is implanted.

대표청구항 ▼

[ What is claimed is:] [1.] A coated wound dressing for sealing a wound in an internal tissue or organ when placed in contact with the wound, comprising: a fibrous wound dressing coated with an adjunctive polymer system to form the coated wound dressing, wherein the adjunctive polymer system compris

[ What is claimed is:] [1.] A coated wound dressing for sealing a wound in an internal tissue or organ when placed in contact with the wound, comprising: a fibrous wound dressing coated with an adjunctive polymer system to form the coated wound dressing, wherein the adjunctive polymer system comprises a pharmaceutically acceptable, biodegradable thermoplastic polymer that is insoluble in water or body fluids mixed with a biocompatible organic solvent which solubilizes the polymer and is miscible to dispersible in water or body fluids and capable of dissipating or dispersing from the adjunctive polymer system into surrounding tissue fluid whereupon the organic solvent dissipates or disperses into the surrounding tissue and the thermoplastic polymer coagulates to form a solid matrix, the proportion of thermoplastic polymer and solvent, and the polymer molecular weight being selected so as to provide said dissipation or dispersion and said coagulation.