$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-005/00
출원번호 US-0711289 (1996-08-21)
발명자 / 주소
  • Jolesz Ferenc A.
  • Hynynen Kullervo
출원인 / 주소
  • Brigham & Women's Hospital
대리인 / 주소
    Choate, Hall & Stewart
인용정보 피인용 횟수 : 84  인용 특허 : 0

초록

Image-guide methods and apparatus for ultrasound delivery of compounds through the blood-brain barrier to selected locations in the brain target a selected location in the brain and applying ultrasound to effect in the tissues and/or fluids at that location a change detectable by imaging. At least a

대표청구항

[ In view thereof, what we claim is:] [1.] A method for delivering a compound from the bloodstream to a selected location in the brain, the method comprising:A. applying ultrasound to a selected location in the brain to effect at that location a change detectable by imaging,B. generating a radiologi

이 특허를 인용한 특허 (84)

  1. Vortman, Kobi; Vitek, Shuki; Ezion, Avner, Acoustic beam forming in phased arrays including large numbers of transducer elements.
  2. Vortman, Kobi; Vitek, Shuki; Levy, Yoav, Adaptive active cooling during focused ultrasound treatment.
  3. Hynynen, Kullervo; McDannold, Nathan, Adaptive ultrasound delivery system.
  4. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Anesthetic injection system.
  5. Zhong Pei ; Cocks Franklin H. ; Preminger Glenn M. ; Lin Haifan, Apparatus and method for macromolecule delivery into living cells.
  6. Freundlich, David; Vortman, Jacob; Yagel, Roni; Vitek, Shuki; Brenner, Naama, Apparatus for controlling thermal dosing in a thermal treatment system.
  7. Vitek, Shuki; Vortman, Kobi, Asymmetric ultrasound phased-array transducer for dynamic beam steering to ablate tissues in MRI.
  8. Nagatani, Yukinori, Biological measurement apparatus and biological stimulation apparatus.
  9. Nagatani, Yukinori, Biological measurement apparatus and biological stimulation apparatus.
  10. Hynynen, Kullervo H.; McDannold, Nathan J., Blood-brain barrier opening.
  11. Zadicario, Eyal; Hananel, Arik; Schiff, Gilat; Grinfeld, Javier, Closed-loop clot lysis.
  12. Mehlen, Patrick; Bredesen, Dale E.; Calheiros-Lourenco, Filipe; Galvan, Veronica, Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders.
  13. Wechter, Stephen R., Compositions for culturing spirochetes.
  14. Vortman, Kobi; Vitek, Shuki; Freundlich, David, Controlled, non-linear focused ultrasound treatment.
  15. Raghavan, Raghu; Poston, Timothy, Creating, directing and steering regions of intensity of wave propagation in inhomogeneous media.
  16. Raghavan, Raghu; Sarvazyan, Armen P., Device, methods, and control for sonic guidance of molecules and other material utilizing time-reversal acoustics.
  17. Smith, Terry J.; Douglas, Raymond S., Diagnostic methods relating to Graves' disease and other autoimmune disorders.
  18. Vitek, Shuki; Hertzberg, Yoni, Efficient ultrasound focusing.
  19. Kyle, Albert; Mason, Martin, Encephalic insonication.
  20. Vitek, Shuki; Schmidt, Rita; Seginer, Amir, Estimation of alignment parameters in magnetic-resonance-guided ultrasound focusing.
  21. Shalev, Alon, External stimulation of the SPG.
  22. Wurster, Walter William; Gustafson, Michael Allen; Pelletier, Elaine Patrice; Waltz, Richard Alan, Focused ultrasonic transducer navigation system.
  23. Wurster, Walter William; Gustafson, Michael Allen; Pelletier, Elaine Patrice; Waltz, Richard Alan, Focused ultrasonic transducer navigation system.
  24. Liu, Hao-Li; Tsai, Hong-Chieh; Lu, Yu-Jen; Wei, Kuo-Chen, Focused ultrasound guiding system and method thereof.
  25. Vitek, Shuki; Vortman, Kobi, Focused ultrasound system for surrounding a body tissue mass and treatment method.
  26. Schmidt, Rita; Vitek, Shuki, Focused ultrasound system with far field tail suppression.
  27. Prus, Oleg; Vitek, Shuki, Focusing ultrasound into the brain through the skull by utilizing both longitudinal and shear waves.
  28. Lorian, Adi; Benary, Raphael, Greater palatine canal stylet.
  29. Vortman, Kobi; Medan, Yoav; Ezion, Avner, Hierarchical switching in ultra-high density ultrasound array.
  30. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Imaging-guided anesthesia injection systems and methods.
  31. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Imaging-guided anesthetic injection method.
  32. Dayan, Avinoam; Dvorsky, Israel; Altman, Hernan, Implant and delivery system for neural stimulator.
  33. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Injection system for delivering multiple fluids within the anatomy.
  34. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Injection systems for delivery of fluids to joints.
  35. Solberg, Yoram; Altman, Hernan, Long-term SPG stimulation therapy for prevention of vascular dementia.
  36. Magnin, Paul A.; Herken, Ulrich; Kyle, Albert S., Low intensity directed ultrasound (LODUS) mediated blood brain barrier disruption.
  37. Chang, Hsu; Yao, Ching; Hwang, San-Chao, Magnetic resonance imaging system.
  38. Medan, Yoav; Hertzberg, Yoni; Maor, Dov, Mapping ultrasound transducers.
  39. Medan, Yoav; Hertzberg, Yoni; Maor, Dov, Mapping ultrasound transducers.
  40. Moehring,Mark A.; Voie,Arne H.; Spencer,Merrill P., Method and apparatus for automatic location of blood flow with Doppler ultrasound.
  41. Pananakis, Dimitrios; Harvey, Paul Royston, Method and device for obtaining information about a mammalian body.
  42. Prausnitz, Mark R.; Liu, Jin; Lewis, Thomas N., Method of applying acoustic energy effective to alter transport or cell viability.
  43. Patrick, Timothy; Knostman, Richard; Ramey, Carribeth; Axelrod, Michael, Method of treating a joint using an articular injection system.
  44. Brisken, Axel F.; Zuk, Robert; McKenzie, John R.; Cowan, Mark W., Methods and apparatus for uniform transcutaneous therapeutic ultrasound.
  45. Yoo, Seung-Schik; Bystritsky, Alexander; McDannold, Nathan; Jolesz, Ferenc A., Methods for modifying electrical currents in neuronal circuits.
  46. Patrick, Timothy; Knostman, Richard; Ramey, Carribeth; Axelrod, Michael, Methods of injecting fluids into joints using a handpiece assembly.
  47. Vortman, Jacob; Medan, Yoav; Assif, Benny, Motion compensated image-guided focused ultrasound therapy system.
  48. Vortman, Jacob; Medan, Yoav; Assif, Benny; Levy, Yoav, Motion compensated image-guided focused ultrasound therapy system.
  49. Vitek, Shuki; Hertzberg, Yoni; Medan, Yoav, Multi-segment ultrasound transducers.
  50. Yeaman, Michael R.; Yount, Nannette Y.; Edwards, Jr., John E.; Brass, Eric P., Multifunctional context-activated protides and methods of use.
  51. Lamensdorf, Itschak; Dayan, Avinoam; Altman, Hernan, Neuroprotective electrical stimulation.
  52. Lamensdorf, Itschak; Dayan, Avinoam; Altman, Hernan, Post-acute electrical stimulation treatment of adverse cerebrovascular events.
  53. Liu, Hao-Li; Tsai, Chih-Hung; Wei, Kuo-Chen; Chen, Pin-Yuan, Processing system and processing method for confocally emitting and receiving ultrasound.
  54. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, Removable cassette for articular injection system.
  55. Lamensdorf, Itschak; Dayan, Avinoam; Altman, Hernan, SPG stimulation.
  56. Shalev, Alon, SPG stimulation for treating complications of subarachnoid hemorrhage.
  57. Shalev, Alon; Gross, Yossi; Altman, Hernan; Dayan, Avinoam; Degtyar, Leonid; Lorian, Adi; Natan, Amir, SPG stimulation via the greater palatine canal.
  58. Hynynen,Kullervo; Clement,Gregory T., Shear mode diagnostic ultrasound.
  59. Hynynen,Kullervo; Clement,Gregory T., Shear mode therapeutic ultrasound.
  60. Shalev,Alon; Natan,Amir, Stimulation for acute conditions.
  61. Lamensdorf, Itschak; Dayan, Avinoam; Altman, Hernan, Stimulation for treating brain events and other conditions.
  62. Mishelevich, David J., Stimulation method via deep brain stimulation.
  63. Shalev, Alon; Gross, Yossi, Stimulation of the OTIC ganglion for treating medical conditions.
  64. Gross, Yossi; Shalev, Alon; Benary, Raphael; Lorian, Adi, Surgical tools and techniques for stimulation.
  65. Konofagou, Elisa E.; Pernot, Mathieu, System and method for electromechanical wave imaging of body structures.
  66. Patrick, Timothy; Knostman, Richard; Axelrod, Michael; Ramey, Carribeth, System for injecting fluids in a subject.
  67. Konofagou, Elisa E.; Fung-Kee-Fung, Simon; Wang, Shougang; Lee, Wei-Ning, Systems and method for composite elastography and wave imaging.
  68. Konofagou, Elisa; Provost, Jean, Systems and methods for matching and imaging tissue characteristics.
  69. Konofagou, Elisa; Provost, Jean, Systems and methods for matching and imaging tissue characteristics.
  70. Konofagou, Elisa E.; Choi, James J.; Borden, Mark A., Systems and methods for opening a tissue.
  71. Konofagou, Elisa E.; Choi, James J., Systems and methods for opening of a tissue barrier.
  72. Konofagou, Elisa E.; Choi, James J., Systems and methods for opening of a tissue barrier.
  73. Konofagou, Elisa E.; Teichert, Tobias; Ferrera, Vincent P.; Marquet, Fabrice; Teng, Yao-Sheng; Wu, Shih-Ying, Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening.
  74. Friedman, Zvi; Maor, Dov, Systems and methods for steering a focused ultrasound array.
  75. Provost, Jean; Konofagou, Elisa E.; Hou, Gary Yi; Chen, Jiangang, Systems and methods of high frame rate streaming for treatment monitoring.
  76. Levy, Yoav; Hananel, Arik; Freundlich, David; Halevy, Gilad; Assif, Benny; Ziso, Hadas, Techniques for correcting measurement artifacts in magnetic resonance thermometry.
  77. Levy, Yoav; Hananel, Arik; Freundlich, David; Halevy, Gilad; Assif, Benny; Ziso, Hadas, Techniques for correcting measurement artifacts in magnetic resonance thermometry.
  78. Schmidt, Rita; Ziso, Hadas; Assif, Benny; Dogadkin, Osnat; Freundlich, David; Levy, Yoav; Vitek, Shuki, Techniques for temperature measurement and corrections in long-term magnetic resonance thermometry.
  79. Alexandrov, Andrei V.; Aronowski, Jaroslaw A.; Wojner, Anne W., Therapeutic methods and apparatus for use of sonication to enhance perfusion of tissue.
  80. Axel Brisken ; Robert Zuk ; John McKenzie ; Jeff Isner ; Meno Nassi, Ultrasonic enhancement of drug injection.
  81. Uhlendorf Volkmar,DEX ; Fritzsch Thomas,DEX ; Siegert Joachim,DEX, Ultrasonic processes and circuits for performing them.
  82. Konofagou, Elisa E.; Provost, Jean; Luo, Jianwen; Okrasinski, III, Stanley J.; Thiébaut, Stéphane; Nguyen, Vu Thanh-Hieu, Ultrasound devices methods and systems.
  83. Hynynen, Kullervo; Clement, Gregory T., Ultrasound therapy.
  84. Maor, Dov; Grinfeld, Javier; Hynynen, Kullervo, Ultrasound therapy.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로