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Composition and method for revitalizing scar tissue 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/08
  • A23J-001/10
  • C08H-001/06
출원번호 US-0465141 (1995-06-05)
발명자 / 주소
  • Lee Clarence C.
출원인 / 주소
  • C.R. Bard, Inc.
대리인 / 주소
    Jones & Askew, LLP
인용정보 피인용 횟수 : 39  인용 특허 : 18

초록

A composition and method are provided that are effective in revitalizing scar tissue by introducing a bioactive substance having angiogenic activity into the scar tissue. The bioactive substance can be introduced by itself, or it can be introduced into the scar tissue in a timed release form. The pr

대표청구항

[ What is claimed is:] [1.] A composition for revitalizing pre-existing scar tissue in a human or animal comprising a naturally occurring growth factor and a biodegradable matrix, wherein the composition revitalizes the pre-existing scar tissue when injected into the pre-existing scar tissue, and wh

이 특허에 인용된 특허 (18)

  1. Silver Frederick A. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Birk David E. (Somerset NJ) Weadock Kevin (Piscataway NJ) Whyne Conrad (Somerset NJ), Biodegradable matrix and methods for producing same.
  2. Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Doillon Charles J. (Edison NJ) Weadock Kevin (Piscataway NJ) Whyne Conrad (Edgewood MD), Biodegradable matrix and methods for producing same.
  3. Silver Fred (Bangor PA) Sharma Vinay (Long Valley NJ) Berndt Dieter R. (Allenwood NJ) Marn Louis E. (Morris Plains NJ), Collagen-based wound dressing and method for applying same.
  4. Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates.
  5. Gottlieb Sheldon K. (8708 Wandering Trail Drive Potomac MD 20854), Compositions containing collagen and methods of use for repairing depressed cutaneous scars.
  6. Vallee Bert L. (Brookline MA) King Thomas V. (Winchester MA), Implants for the promotion of healing of meniscal tissue.
  7. Smestad Thomas L. (Palo Alto CA) McPherson John (Sunnyvale CA) Wallace Donald G. (Menlo Park CA), Injectable cross-linked collagen implant material.
  8. Yamahira Yoshiya (Kobe JPX) Fujioka Keiji (Amagasaki JPX) Sato Shiegeji (Ibaraki JPX) Takada Yoshihiro (Takatsuki JPX), Long-term sustained-release preparation.
  9. Gottlieb Sheldon K. (8708 Wandering Trail Dr. Potomac MD 20854), Method for enhancing the healing of grafted tissue.
  10. Pickart Loren R. (Bellevue WA), Method for inducing biological coverings in wounds.
  11. Fujioka Keiji (Amagasaki JPX) Sato Shigeji (Ibaraki JPX) Sasaki Yoshio (Ibaraki JPX) Miyata Teruo (Tokyo JPX) Furuse Masayasu (Sagamihara JPX) Naito Hiromi (Tokyo JPX), Method for producing sustained release formulation.
  12. Gottlieb Sheldon K. (8708 Wandering Trail Dr. Potomac MD 20854), Method for promoting growth of new connective tissue over surface wounds.
  13. Sottiurai Vikrom S. (5812 Virginia Pl. Metairie LA 70003), Method for reducing the occurrence of distal anastomotic intimal hyperplasia using fractionated heparin.
  14. Vallee Bert L. (Brookline MA) King Thomas V. (Winchester MA), Promotion of healing of meniscal tissue.
  15. Ersek Robert A. (62 Pascal Austin TX 78746) Beisang Arthur A. (1035 Lake Beach Dr. Shoreview MN 55126) Beisang ; III Arthur A. (4 Falcon La. St. Paul MN 55127-6317), Textured micro implants.
  16. Luck Edward E. (Menlo Park CA) Brown Dennis M. (Menlo Park CA), Treatments employing drug-containing matrices for introduction into cellular lesion areas.
  17. Antoniades Harry N. (Newton MA) Lynch Samuel E. (Jamaica Plain MA) Williams Ray C. (Arlington MA), Wound healing and bone regeneration using PDGF and IGF-I.
  18. Sundsmo John S. (Pleasanton CA) Ksander George A. (Menlo Park CA) McPherson John M. (Sunnyvale CA), Wound-healing composition.

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  3. Nicolson, Donald Magnus; Halliday, Janet Anne; Tuominen, Jukka; Zurutuza, Amaia, Bioresorbable polymers.
  4. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  5. Freddo,Mary Ellen; Keum,Ki Chang; Yoo,Naechoon; Yoo,Won Min, Compositions and methods for the treatment of wounds and the reduction of scar formation.
  6. Tsubouchi,Kozo; Yamada,Hiromi, Extraction and utilization of cell growth-promoting peptides from silk protein.
  7. Bhatia, Mohit; Lugo, Chris; Ye, Qian; Edinger, James W., Human placental collagen compositions and methods of making and using the same.
  8. Bhatia, Mohit; Lugo, Chris; Ye, Qian; Edinger, James W., Human placental collagen compositions, and methods of making and using the same.
  9. Bhatia, Mohit; Lugo, Chris; Ye, Qian; Edinger, James W., Human placental collagen compositions, and methods of making and using the same.
  10. Bhatia, Mohit; Lugo, Chris; Ye, Qian; Edinger, James W., Human placental collagen compositions, and methods of making and using the same.
  11. Bhatia, Mohit; Lugo, Chris; Ye, Qian; Edinger, James W., Human placental collagen compositions, and methods of making and using the same.
  12. Zeitels, Steven M.; Hillman, Robert E.; Karajanagi, Sandeep Sidram; Langer, Robert S., Hydrogels for vocal cord and soft tissue augmentation and repair.
  13. Zeitels, Steven M.; Hillman, Robert Edward; Karajanagi, Sandeep Sidram; Langer, Robert S., Hydrogels for vocal cord and soft tissue augmentation and repair.
  14. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark Alexander; Halliday, Janet Anne, Hydrophilic polyurethane compositions.
  15. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark; Halliday, Janet Anne, Hydrophilic polyurethane compositions.
  16. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
  17. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
  18. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  19. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  20. Beaulieu, Andre; Paquin, Robert, Method of producing concentrated non-buffered solutions of fibronectin.
  21. Yoo, Won Min; Chang, Kyung Hee; Yoo, Nae Choon; Keum, Ki Chang; Lee, Sang Yup; Lee, Gene, Method of treating a wound with acidified plasma or serum.
  22. Zeitels, Steven M.; Hillman, Robert E.; Karajanagi, Sandeep Sidram; Langer, Robert S., Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production.
  23. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark; Halliday, Janet A., Polyurethane elastomers.
  24. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark; Halliday, Janet Anne, Polyurethane elastomers.
  25. Kleinsek, Donald A.; Soto, Adriana, Removal of hypertrophic scars.
  26. Milbocker, Michael T., Situ bulking device.
  27. Beaulieu,Andre; Paquin,Robert; Lariviere,Benoit, Solid wound healing formulations containing fibronectin.
  28. Chancellor, Michael B.; Tyagi, Pradeep; Fraser, Matthew O.; Chuang, Yao-Chi; de Groat, William C; Huang, Leaf; Yoshimura, Naoki, Sphingomyelin liposomes for the treatment of hyperactive bladder disorders.
  29. Robertson, Steven, Stabilised prostaglandin composition.
  30. Robertson, Steven, Stabilised prostaglandin composition.
  31. Robertson, Steven, Stabilised prostaglandin composition.
  32. Grunze, Michael; Fritz, Ulf, Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface.
  33. Kleinsek, Don A., Tissue treatments with adipocyte cells.
  34. Milbocker,Michael T., Treatment for Gastroesophageal disease.
  35. Milbocker,Michael T, Treatment for gastroesophageal disease.
  36. Liu, Qing; Rendon Barragan, Henry; Matcham, George, Umbilical cord biomaterial for medical use.
  37. Halliday, Janet A.; Tuominen, Jukka; Livingstone, Mark; Koppenhagen, Frank; Currie, Lilias; Stewart, Sarah, Water-swellable polymers.
  38. Halliday, Janet A.; Tuominen, Jukka; Livingstone, Mark; Koppenhagen, Frank; Currie, Lilias; Stewart, Sarah, Water-swellable polymers.
  39. Halliday, Janet Anne; Tuominen, Jukka; Livingstone, Mark Alexander; Koppenhagen, Frank; Currie, Lilias Morton; Stewart, Sarah, Water-swellable polymers.
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