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RNA separation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-021/02
출원번호 US-0706260 (1996-09-04)
발명자 / 주소
  • Mehra Manmohan
출원인 / 주소
  • Biotecx Laboratories, Inc.
대리인 / 주소
    Bush, Riddle & Jackson
인용정보 피인용 횟수 : 29  인용 특허 : 8

초록

An improved process for the separation of RNA from a liquid sample of biological origin containing RNA comprises (a) intimately contacting the sample with a two-phase composition wherein the upper phase is predominately phenol and the lower phase is an aqueous solution comprising at least one water-

대표청구항

[ What is claimed is:] [1.] In the process of separating RNA from biological samples containing RNA by contacting the sample with a two-phase composition wherein the upper phase is predominately phenol and the lower phase is an aqueous solution containing at least one water-soluble guanidinium salt,

이 특허에 인용된 특허 (8)

  1. Goldrick Marianna (Pfluegerville TX) Winkler Matthew (Austin TX), Methods for the recovery of nucleic acids from reaction mixtures.
  2. Ness Jeffrey V. (Bothell WA) Cimler B. Melina (Portland OR) Meyer ; Jr. Rich B. (Woodinville WA) Vermeulen Nicolaas M. J. (Woodinville WA), Non toxic compositions and methods useful for the extraction of nucleic acids.
  3. Van Ness Jeffrey (Bothell WA) Cimler B. Melina (Portland OR) Meyer ; Jr. Rich B. (Woodinville WA) Vermeulen Nicolaas M. J. (Woodinville WA), Non-corrosive compositions and methods useful for the extraction of nucleic acids.
  4. Boom Willem R. (Amsterdam NLX) Adriaanse Henritte M. A. (Arnhem NLX) Kievits Tim (The Hague NLX) Lens Peter F. (Amsterdam NLX), Process for isolating nucleic acid.
  5. Holmes David S. (Troy NY), Process for the rapid and simple isolation of nucleic acids.
  6. Chomczynski Piotr (727 Martin Luther King Dr. Cincinnati OH 45220), Product and process for isolating RNA.
  7. Macfarlane Donald E. (Iowa City IA), Quaternary amine surfactants and methods of using same in isolation of nucleic acids.
  8. Chomczynski Piotr (778 Avon Fields La. Cincinnati OH 45229), Shelf-stable product and process for isolating RNA, DNA and proteins.

이 특허를 인용한 특허 (29)

  1. Bost, Douglas A.; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  2. Bost, Douglas A.; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  3. Bost, Douglas; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  4. Bost,Douglas A.; Greenfield,Lawrence, Compositions and methods of selective nucleic acid isolation.
  5. Whitney, Scott E.; Wilkinson, Steven; Muller, Rolf, Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures.
  6. Whitney, Scott E.; Ghirmai, Senait; Muller, Rolf, Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures.
  7. Whitney, Scott E.; Wilkinson, Steven; Muller, Rolf, Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures.
  8. Whitney, Scott E.; De Los Rios, Stephanie; Ghirmai, Senait; Muller, Rolf; Liberal, Vasco; Wilkinson, Steven P., Formulations and methods for stabilizing PCR reagents.
  9. Danenberg, Kathleen; Danenberg, Peter V.; Swenson, Steven, Isolation of RNA, DNA and proteins from formalin-fixed paraffin-embedded tissue specimens.
  10. Augello, Frank A.; Rainen, Lynne; Walenciak, Matthew; Oelmuller, Uwe; Wyrich, Ralf; Bastian, Helge, Method and device for collecting and stabilizing a biological sample.
  11. Danenberg Kathleen ; Danenberg Peter V. ; Swenson Steven, Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens.
  12. Kanaoka, Shigeru, Method of detecting colon cancer marker.
  13. Kanaoka, Shigeru, Method of detecting colon cancer marker.
  14. Danenberg, Kathleen D., Method of determining Dihydropyrimidine dehydrogenase gene expression.
  15. Danenberg, Kathleen D., Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression.
  16. Danenberg,Kathleen D., Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression.
  17. Danenberg,Kathleen D., Method of determining a chemotherapeutic regimen based on ERCC1 expression.
  18. Danenberg, Kathleen D., Method of determining a chemotherapeutic regimen based on and expression.
  19. Danenberg, Kathleen D., Method of determining a chemotherapeutic regimen based on and expression.
  20. Danenberg,Kathleen D., Method of determining a chemotherapeutic regimen based on glutathione-s transferase pi expression.
  21. Danenberg, Kathleen D., Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors.
  22. Danenberg, Kathleen D., Method of determining dihydropyrimidine dehydrogenase gene expression.
  23. Danenberg,Kathleen D., Method of determining dihydropyrimidine dehydrogenase gene expression.
  24. Danenberg, Kathleen; Danenberg, Peter V.; Swenson, Steven, Quantitative measurement of gene expression based on isolation of RNA from formalin-fixed paraffin-embedded tissue specimens.
  25. Belly,Robert; Toner,Jacqueline; Backus,John, Rapid extraction of RNA from cells and tissues.
  26. Hossain, Ashfaque; Hanson, Nancy Jo Dohse; Reisbig, Mark D., Rapid nucleic acid isolation method and compositions.
  27. Baker, Tony, Removal of molecular assay interferences.
  28. Muller, Rolf; Desharnais, Joel; Wilkinson, Steven P.; Arendt, Victoria; Diaz, Paul, Stabilization of thrombocytes at ambient temperatures.
  29. Helftenbein, Elke, Vessel for blood sampling.
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