초록 ▼

One preferred embodiment utilizes differential measurement of radiation that migrated in two migration paths between two source (100) detector (110) pairs placed on the head in a manner that each path is localized in a portion of one hemisphere. The present invention also provides in various embodim

One preferred embodiment utilizes differential measurement of radiation that migrated in two migration paths between two source (100) detector (110) pairs placed on the head in a manner that each path is localized in a portion of one hemisphere. The present invention also provides in various embodiments of spectrophotometer systems for in vivo examination of a tissue of a human by measuring changes in electromagnetic radiation scattered and absorbed in a migration path in the tissue. Generally, the spectrophotometer systems comprise a light source for introducing the radiation into the tissue, a detector for detecting radiation that has migrated in the tissue, processing means for processing signals of the detected radiation to create processed data, and evaluation means for determining physiological or pathophysiological changes in the tissue of interest. The present invention also provides for determining the metabolic condition of an aerobically stressed portion of tissue such as the muscle tissue of an exercising person.

대표청구항 ▼

[ What is claimed is:] [1.] A spectrophotometer for measuring a condition of a biological tissue of a subject, comprising:a body-conformable support constructed to be mounted on the skin of the subject;a light source optically connected to an input port located in said support;a light detector optic

[ What is claimed is:] [1.] A spectrophotometer for measuring a condition of a biological tissue of a subject, comprising:a body-conformable support constructed to be mounted on the skin of the subject;a light source optically connected to an input port located in said support;a light detector optically connected to a detection port included in said support in a laterally spaced-apart arrangement from said input port establishing photon lateral-scatter paths through the tissue of interest;an adjustable mechanism constructed to vary the spacing between said input port and said detection port by moving one of said ports relative to said support, the spacing between said ports being several centimeters and being adapted to extend along a surface of the examined tissue, said spacing determining the depth of penetration of the introduced light migrating over lateral scatter-paths in said tissue;an opaque barrier included in said body-conformable support and exposed for contact with the skin, said barrier influencing the lateral scatter paths by preventing substantially detection of light migrating laterally in subcutaneous layers; anda processor, including circuitry receiving a wavelength specific detection signal from said detector, constructed and arranged to determine a condition of the examined tissue.