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Cushioning beads and tablet comprising the same capable of forming a suspension 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
출원번호 US-0709415 (1996-09-06)
발명자 / 주소
  • Habib Yacoub S.
  • Shangraw Ralph
  • Augsburger Larry L.
출원인 / 주소
  • University of Maryland, Baltimore
대리인 / 주소
    Sughrue, Mion, Zinn, Macpeak & Seas, PLLC
인용정보 피인용 횟수 : 54  인용 특허 : 4

초록 ▼

Cushioning beads comprising microcrystalline cellulose and a disintegrant (preferably croscarmellose sodium) are disclosed. The cushioning beads are prepared by extrusion-spheronization, followed by freeze-drying. Also disclosed, are water-dispersible tablets having high tensile strength, comprising

대표청구항

[ What is claimed:] [1.] A cushioning bead comprising microcrystalline cellulose, wherein said cushioning bead is prepared by extrusion-spheronization, followed by freeze-drying, wherein said cushioning bead has a diameter of about 0.2-2.0 mm.

이 특허에 인용된 특허 (4)

  1. Doyon Daniel J. (Florida NY) Ganesan Madurai G. (Suffern NY) Preston Wendy A. (Suffern NY) Sheth Nitin V. (Middletown NY), Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form.
    상세보기
  2. Ventouras Kimon (Le Lignon CHX), Galenical formulation.
    상세보기
  3. Ibsen Lars S. (Frederiksberg DKX), Oral composition containing particles comprising an active substance.
    상세보기
  4. Mehra Dev K. (Furlong PA) Ibrahim Nagui I. (East Windsor NJ) Fleck ; Jr. Edwin G. (Newark DE), Solid dosage forms.
    상세보기

이 특허를 인용한 특허 (54)

  1. Guimberteau, Florence; Dargelas, Frederic, Anti-misuse microparticulate oral pharmaceutical form.
    상세보기
  2. Guimberteau, Florence; Dargelas, Frédéric, Anti-misuse microparticulate oral pharmaceutical form.
    상세보기
  3. Kamatsuchi, Yoshinori; Miyakoshi, Takao, Composition for treatment of ballast water.
    상세보기
  4. Odidi, Isa; Odidi, Amina, Controlled extended drug release technology.
    상세보기
  5. Haggard, Warren Oliver; Kaufman, Michael Earl; Parr, Jack Eldon; Morris, Linda, Controlled release composite.
    상세보기
  6. Haggard,Warren Oliver; Kaufman,Michael Earl; Parr,Jack Eldon; Morris,Linda, Controlled release composite.
    상세보기
  7. Odidi, Isa; Odidi, Amina, Controlled release delivery device comprising an organosol coat.
    상세보기
  8. Zougari, Mohammed I.; Hammami, Ahmed; Karan, Kunal; Jacobs, Scott; Ratulowski, John, Couette device and method to study solids deposition from flowing fluids.
    상세보기
  9. Propst, Cecil W.; Meadows, Marc W.; Todd, Michael S., Crystalline microspheres and the process of manufacturing the same.
    상세보기
  10. Propst, Cecil W.; Meadows, Marc W.; Todd, Michael S., Crystalline microspheres and the process of manufacturing the same.
    상세보기
  11. Penhasi, Adel; Flashner, Moshe; Lerner, E. Itzhak, Delayed total release two pulse gastrointestinal drug delivery system.
    상세보기
  12. Wilber, William R.; Guo, Jian-Hwa; Greenberg, Edward S., Directly compressed solid dosage articles.
    상세보기
  13. deVries, Tina; Gold, Lynn, Doxycycline metal complex in a solid dosage form.
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  14. Cocolas, Harry G.; Hollis, Christin P., Encased-pellet tablets.
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  15. Anaebonam Aloysius O. ; Clemente Emmett ; Mendes Robert W., Extended release acetaminophen.
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  16. Clemente Emmett ; Anaebonam Aloysius O. ; Mendes Robert W. ; Fawzy Abdel A. ; Morrel Eric M., Extended release acetaminophen particles.
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  17. Neidle, Bruce; Newman, Kenneth; Sweeney, William R.; Hayes, Cynthia S.; Mitten, Robert T.; Crawford, Danielle R., Flavor pouch.
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  18. Neidle, Bruce; Newman, Kenneth; Sweeney, William R.; Hayes, Cynthia S.; Mitten, Robert T.; Crawford, Danielle R., Flavor pouch.
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  19. Neidle, Bruce; Newman, Kenneth; Sweeney, William R.; Hayes, Cynthia S.; Mitten, Robert T.; Crawford, Danielle R., Flavor pouch.
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  20. Neidle, Bruce; Newman, Kenneth; Sweeney, William R.; Hayes, Cynthia S; Mitten, Robert T.; Crawford, Danielle R, Flavor pouch.
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  21. Bakan, Douglas A.; Jitpraphai, Waranush; Newhard, Steven B.; Wortzman, Mitchell S., Gastroretentive dosage forms for doxycycline.
    상세보기
  22. Park, Sang Yeob; Lim, Hye Jung, Highly robust fast-disintegrating tablet and process for manufacturing the same.
    상세보기
  23. Lerner, E. Itzhak; Flashner, Moshe; Penhasi, Adel, Immediate release gastrointestinal drug delivery system.
    상세보기
  24. Kiczek ; Sr. Alexander P. ; Wong Mike, Method for encapsulating reactive dental agents.
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  25. Shinal Edward C., Method for preparation of disodium pamidronate.
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  26. Shinal Edward C., Method for preparation of disodium pamidronate.
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  27. Shinal, Edward C., Method for preparation of disodium pamidronate.
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  28. Bender,Martin P.; Verbarg,Donald P., Method for producing small granules.
    상세보기
  29. Augsburger, Larry; Do, Ngoc; He, Min Michael; Yu, Cheng Der Tony, Methods for making pharmaceutical dosage forms containing active cushioning components.
    상세보기
  30. Vladyka, Jr., Ronald S.; Erkoboni, David F.; Sweriduk, Christopher A., Microcrystalline cellulose cushioning granules.
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  31. McTeigue Daniel ; Shah Indukumar G. ; Swider Karen ; Wynn David W., Microcrystalline cellulose particles having active core.
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  32. Legrand, Valérie; Castan, Catherine; Meyrueix, Rémi; Soula, Gérard, Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles.
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  33. Hayes, David; LoPore, Angelo; Lukas, Stefan; Quinn, Eugene, Modified release coated drug preparation.
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  34. Guimberteau, Florence; Dargelas, Frederic; Soula, Gérard; Soula, Rémi, Oral dosage form comprising an antimisuse system.
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  35. Odidi, Isa; Odidi, Amina, Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors.
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  36. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
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  37. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
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  38. Cheng, Taiben; Griscik, Greg J.; Gee, Diane L., Oral pouch products with immobilized flavorant particles.
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  39. Odidi, Isa; Odidi, Amina, Pharmaceutical composition having reduced abuse potential.
    상세보기
  40. Wang, Zhaolin; Finlay, Warren H., Powder formation by atmospheric spray-freeze drying.
    상세보기
  41. Habib, Walid; Kothari, Bhaveshkumar, Prednisolone salt formulations.
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  42. Odidi, Isa; Odidi, Amina, Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient.
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  43. Odidi, Isa; Odidi, Amina, Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient.
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  44. Odidi, Isa; Odidi, Amina, Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems.
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  45. Wolfgang A. Ritschel ; Mukul A. Agrawal, Self-destructing, controlled release peroral drug delivery system.
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  46. Chenevier, Philippe; Marechal, Dominique, Spheroids and multiparticulate tablets comprising them.
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  47. Borgeat, Pierre, Stabilized leukotriene B4 (LTB4) agent pharmaceutical formulation.
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  48. Abramowitz,Robert; O'Donoghue,Denise M.; Jain,Nemichand B., Sustained release beadlets containing stavudine.
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  49. Kumbhani,Davejibhai; Pandya,Harish B.; Patel,Hiren, Sustained release pharmaceutical preparations and methods for producing the same.
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  50. Crawford, Danielle R.; Brooks, Karen; Newman, Kenneth A.; Sweeney, William R.; Chappell, Sr., Fernando L., Tobacco-free oral flavor delivery pouch product.
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  51. Crawford, Danielle R.; Brooks, Karen; Newman, Kenneth A.; Sweeney, William R.; Chappell, Sr., Fernando L., Tobacco-free oral flavor delivery pouch product.
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  52. Mishra, Munmaya K.; Duan, Biao; Wu, Daqing; Sweeney, William R., Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release.
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  53. Mishra, Munmaya K.; Duan, Biao; Wu, Daqing; Sweeney, William R., Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release.
    상세보기
  54. Brun, Philippe, Vehicle cabin air filter, a vehicle including such a filter, and a method of manufacture.
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