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Method for isolating nucleic acids 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-021/00
출원번호 US-0519039 (1995-08-24)
발명자 / 주소
  • Su Xing
출원인 / 주소
  • The Theobald Smith Research Institute, Inc.
대리인 / 주소
    Banner & Witcoff,Ltd.
인용정보 피인용 횟수 : 48  인용 특허 : 14

초록

The invention features a method of isolating nucleic acid in a substantially purified form, including the steps of: a) contacting a biological sample which contains aggregated nucleic acid with a matrix comprising a solid hydrophilic organic polymer without an effective positive charge under conditi

대표청구항

[ I claim:] [1.] A method of isolating nucleic acid in a substantially purified form, said method comprising the steps of:a) contacting a biological sample containing nucleic acid with a matrix under conditions which permit said nucleic acid in said sample to bind to said matrix, said matrix consist

이 특허에 인용된 특허 (14)

  1. Clark Carl R. (Rockford IL), Apparatus for rapid immunoassays.
  2. Bojanic Dejan (Kent GB2) Merson James R. (Kent GB2), Assay tray assembly.
  3. Aysta James E. (Stillwater MN) Colpan Metin (Erkrath DEX), Device and a method for separating liquid samples.
  4. Bowers William F. (Topsfield MA) Fulton Scott P. (Brookline MA) Thompson Judith A. (Marblehead MA) Donofrio David M. (Rockport MA) Ivie Kert F. (Spruce Creek PA), Microfiltration apparatus with radially spaced nozzles.
  5. Aysta James E. (Stillwater MN), Multi-well filtration apparatus.
  6. Clark Phillip (Malden MA) Lee Carolyn (Sudbury MA) Rising Donald B. (Stow MA) Zermani Thomas (Concord MA), Multi-well filtration test apparatus.
  7. MacConnell William P. (1849 Rubenstein Dr. Cardiff CA 92007), Nucleic acid purification system and method.
  8. Boom Willem R. (Amsterdam NLX) Adriaanse Henritte M. A. (Arnhem NLX) Kievits Tim (The Hague NLX) Lens Peter F. (Amsterdam NLX), Process for isolating nucleic acid.
  9. Kiefer Hansruedi (Riehen CHX), Process for isolating nucleic acids utilizing protease digestion.
  10. McCormick Randy M. (Wilmington DE), Process for purifying nucleic acids.
  11. Mullis Kary B. (La Jolla CA), Rapid purification of DNA.
  12. Mullis Kary B. (La Jolla CA), Rapid purification of DNA.
  13. Potts Robert S. (Sherborn MA), Self packaged test kit.
  14. Chomczynski Piotr (778 Avon Fields La. Cincinnati OH 45229), Shelf-stable product and process for isolating RNA, DNA and proteins.

이 특허를 인용한 특허 (48)

  1. Parameswaran,Lalitha; Young,Albert; Bortolin,Laura T.; Hollis,Mark A.; Harper,James; Bobrow,Johanna, Apparatus and method for isolating a nucleic acid from a sample.
  2. Bortolin, Laura T.; Parameswaran, Lalitha; Harper, James; Bobrow, Johanna; Hollis, Mark A.; Brown, Drew Chapman; Clasen, Eric Scott; Schmidt, John Calvin, Apparatus for isolating a nucleic acid from a sample.
  3. Heath, Ellen M.; Shuman, Ruth M., Apparatuses and methods for isolating nucleic acid.
  4. Abrams, Ezra S.; Yun, Danny; Barbera, Todd J.; Sabin, Douglas Grosvenor; Boles, T. Christian, Apparatuses, methods and systems for automated processing of nucleic acids and electrophoretic sample preparation.
  5. Blakesley, Robert W.; Goldsborough, Mindy D., Archiving of vectors.
  6. Blakesley, Robert W.; Goldsborough, Mindy D., Archiving of vectors.
  7. Chan, Grace Sze Man; Faramus, Ellie; Lee, Jason Ian Kien Huat; Nair, Chenicheri Hariharan; Roeth, Philip John, Blood-related dialysis and treatment.
  8. Bost, Douglas A.; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  9. Bost, Douglas A.; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  10. Bost, Douglas; Greenfield, Lawrence, Compositions and methods of selective nucleic acid isolation.
  11. Bost,Douglas A.; Greenfield,Lawrence, Compositions and methods of selective nucleic acid isolation.
  12. Regan, John Frederick, Disposable and removable nucleic acid extraction and purification cartridges for automated flow-through systems.
  13. Heath, Ellen M.; Shuman, Ruth M., Eluting reagents, methods and kits for isolating DNA.
  14. Lee, Young sun; Han, Jung im; Lee, Hyo yeon; Namkoong, Kak; Oh, Kwang wook, Isolation and purification method of biomolecules using hydrogel.
  15. Nargessi,Ruhangiz D.; Pourfarzaneh,Matt, Isolation and purification of nucleic acids.
  16. Haddad, Louis C.; Swenson, Barbara C.; Bothof, Catherine A.; Raghavachari, Madhusudan, Materials, methods, and kits for reducing nonspecific binding of molecules to a surface.
  17. Kim, Jong-Hoon; Kim, Min; Park, Hae-Joon; Park, Han Oh, Method for isolating a nucleic acid using particulate matter and a composition therefor.
  18. Mori, Toshihiro; Makino, Yoshihiko; Hando, Rie; Takeshita, Yumiko; Inomata, Hiroko, Method for isolating and purifying a nucleic acid.
  19. Kolzau, Thomas; Pluster, Wilhelm; Ulbricht, Mathias, Method for isolating nucleic acids from a liquid sample containing nucleic acids.
  20. Pullela, Phani Kumar; Manoj, Mulakkapurath Narayanan; Gandhavalla, Santhosh Kumar; Pinto, Mitchell Preetham; Nair, Chandrasekhar Bhaskaran; Subbarao, Pillarisetti Venkata, Method for isolation of nucleic acids and a kit thereof.
  21. Van Kuppevelt, Antonius H. M. S. M.; Veerkamp, Jacobus Henricus; Blank, Thiemo Arnim, Method for linking nucleic acids and/or glycosaminoglycans to polar/hydrophilic materials.
  22. Haddad, Louis C., Method for reducing the amount of nucleic acid adhering to a hydrophobic surface.
  23. Mori,Toshihiro; Makino,Yoshihiko, Method for separating and purifying a nucleic acid.
  24. Yoo, Chang-eun; Kim, Joon-ho; Hwang, Kyu-youn; Lee, Hun-joo; Lim, Hee-kyun; Min, Jun-hong, Method of isolating and purifying nucleic acids using immobilized hydrogel or PEG-hydrogel copolymer.
  25. Coughlin, Richard T.; Crabb, Joseph H., Method of purifying lantibiotics.
  26. Chesnut, Jonathan; Carrino, John; Leong, Louis; Madden, Knut; Gleeson, Martin; Fan, James; Brasch, Michael; Cheo, David; Hartley, James; Byrd, Devon; Temple, Gary, Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites.
  27. Chesnut, Jonathan; Carrino, John; Leong, Louis; Madden, Knut; Gleeson, Martin; Fan, James; Brasch, Michael; Cheo, David; Hartley, James; Byrd, Devon; Temple, Gary, Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites.
  28. Kirchgesser,Michael; Bergmann,Frank; Walter,Thomas; Weindel,Kurt; Zielenski,Ralf; Sarofim,Emad, Methods for isolating nucleic acids.
  29. McKernan, Kevin J.; Gustafson, Erik; Brand, Adrianne D., Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers.
  30. Bitner, Rex M., Methods of optimal purification of nucleic acids and kit for use in performing such methods.
  31. Bitner, Rex M., Methods of purifying a nucleic acid and formulation and kit for use in performing such methods.
  32. Bitner, Rex M., Methods of purifying a nucleic acid and formulation and kit for use in performing such methods.
  33. Luo, Yuling; Yang, Wen, Multiplex branched-chain DNA assays.
  34. Luo, Yuling; Yang, Wen, Multiplex branched-chain DNA assays.
  35. Luo, Yuling; Ma, Yunqing; McMaster, Gary; Nguyen, Quan Ngoc; Witney, Frank; Yang, Wen, Multiplex capture of nucleic acids.
  36. Luo, Yuling; Yang, Wen, Multiplex capture of nucleic acids.
  37. Luo, Yuling; Yang, Wen, Multiplex capture of nucleic acids.
  38. Luo, Yuling; Ma, Yunqing; Nguyen, Cung-Tuong, Multiplex detection of nucleic acids.
  39. Luo, Yuling; Ma, Yunqing; Nguyen, Cung-Tuong, Multiplex detection of nucleic acids.
  40. Luo, Yuling; Ma, Yunqing; Nguyen, Cung-Tuong, Multiplex detection of nucleic acids.
  41. Louis C. Haddad, Nucleic acid isolation by adhering to hydrophobic solid phase and removing with nonionic surfactant.
  42. Heath, Ellen M.; Shuman, Ruth M., Processes for isolating, amplifying and characterizing DNA.
  43. Baker, Tony, Removal of molecular assay interferences.
  44. Moulton Thomas, Simultaneous filtration of numerous samples using microfibers.
  45. Li, Bing; Grossmann, Gregory Andrew; Moore, David Roger, Substrates and associated methods for elution of nucleic acids.
  46. Wu, Xingyong; Wang, Huei-Yu Fay; Su, Nan; Wang, Li-Chong; Luo, Yuling, Ultra sensitive method for in situ detection of nucleic acids.
  47. Wu, Xingyong; Wang, Huei-Yu Fay; Su, Nan; Wang, Li-Chong; Luo, Yuling, Ultra sensitive method for in situ detection of nucleic acids.
  48. Bedingham, William; Robole, Barry W.; Parthasarathy, Ranjani V.; Ericson, Katya, Variable valve apparatus and methods.
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