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Treatment of viral disease with oral interferon-.alpha. 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/21
출원번호 US-0305418 (1994-09-13)
발명자 / 주소
  • Cummins Joseph M.
출원인 / 주소
  • The Texas A&M University System
대리인 / 주소
    Barnes & Thornburg
인용정보 피인용 횟수 : 15  인용 특허 : 25

초록

Viral infections are treated by the administration of alpha-interferon at a dosage of from about 0.01 to about 5 IU/lb./day such that the interferon is held in contact with the patient's oral and pharyngeal mucosae. The IFN-.alpha. is administered in a solid dosage from, e.g., a saliva-dissolvable l

대표청구항

[ I claim:] [1.] A method of treatment of a human patient afflicted with a disease of viral origin using interferon to stimulate an anti-viral response, the method consisting essentially of the steps ofselecting a saliva-soluble solid dosage form of human alpha-interferon,introducing the solid dosag

이 특허에 인용된 특허 (25)

  1. Babaian Eduard A. (Moscow SUX) Gerasimova Galina A. (Moscow SUX) Davydov Anatoly B. (Moscow SUX) Utyamyshev Rustam I. (Moscow SUX) Khromov Gennady L. (Moscow SUX) Metelitsa Vladimir I. (Moscow SUX) V, Antianginal film and method of treating ischemic heart disease.
  2. Stickl Helmut Anton (Starenweg 6 ; 8033 Krailling B. Munich DT), Attenuated fowl pox virus preparation for the treatment of infectious diseases, method for the manufacture thereof, and.
  3. Kwan Henry K. (Summit NJ), Biologically stable alpha-interferon formulations.
  4. Keith Alec D. (Boalsburg PA) Snipes Wallace C. (Pine Grove Mills PA), Buccal drug dosage form.
  5. Eastman James E. (Decatur IL) Moore Carl O. (Rochester IL), Cold-water-soluble granular starch for gelled food compositions.
  6. Sato Mitsunobu (Tokushima JPX) Katsuragi Yasuhiro (Toyonaka JPX) Sakano Yasuo (Amagasaki JPX) Sugihara Kunio (Otsu JPX) Aimoto Kenji (Toyonaka JPX), Composition and method for treating keratosic disorder of skin and mucosa.
  7. Cummins ; Jr. Joseph M. (Amarillo TX), Delivery of biologically active components of heterologous species interferon isolates.
  8. Tsuk Andrew G. (Plattsburgh NY) Martin Frederick H. (West Chazy NY), Dosage form.
  9. Carey Martin C. (Wellesley MA) Moses Alan C. (Waban MA) Flier Jeffrey S. (West Newton MA), Drug administration.
  10. Dalton Barbara J. (Philadelphia PA) Rees Robert C. (Sheffield GB2), Immunomodulation.
  11. Sugimoto Kaname (Okayama JPX) Yuen Shokichi (Okayama JPX), Interferon and preparations containing interferon.
  12. Osther Kurt B. (Naerum DKX) Jensen Werner K. (Roskilde DKX), Interferon product and process for its preparation.
  13. Asculai Samuel S. (East Meadow NY) Rapp Fred (Hershey PA), Interferon-containing compositions.
  14. Krauser Robert S. (444 Taconic Rd. Greenwich CT 06830), Method and apparatus for treating ailments.
  15. Wong Grace H. W. (South San Francisco CA), Method and composition for prophylaxis and treatment of viral infections.
  16. Nagai Tsuneji (Chofu JPX) Machida Yoshiharu (Kawasaki JPX) Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX), Method and preparation for administration to the mucosa of the oral or nasal cavity.
  17. Nagai Tsuneji (Chofu JPX) Machida Yoshiharu (Kawasaki JPX) Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX), Method and preparation for administration to the mucosa of the oral or nasal cavity.
  18. Young Alan S. (Kikuyu TX KEX) Cummins Joseph M. (Amarillo TX), Method for prevention of parasite infections.
  19. Cummins Joseph M. (Amarillo TX), Method of regulating appetite and efficiency of food utilization employing interferon.
  20. Cummins Joseph M. (Amarillo TX), Method of using interferon in low dosage to regulate appetite and efficiency of food utilization.
  21. Hasegawa Kenji (Ibaraki JPX) Sakano Yasuo (Amagasaki JPX) Katsuragi Yasuhiro (Toyonaka JPX) Aimoto Kenji (Toyonaka JPX) Sugihara Kunio (Otsu JPX), Pharmaceutical composition containing interferon in stable state.
  22. Yabrov Alexander A. (45 Wiggins St. Princeton NJ 08540), Prophylaxis or treatment of interferon-sensitive diseases.
  23. Kigasawa Kazuo (Tokyo JPX) Shimizu Hiroaki (Tokyo JPX) Hayashi Toshihiro (Chiba JPX) Watabe Kazuo (Kanagawa JPX) Tanizaki Akira (Tokyo JPX) Koyama Osamu (Tokyo JPX) Wakisaka Kikuo (Tokyo JPX) Ogawa Y, Soft buccal.
  24. Kwiatek Alfred (New York NY) Schwartz Jack W. (Burlington VT), Therapeutic device for the administration of medicaments.
  25. Jost Leonora (R.R. 1 ; Box 130 Oxford ME 04270), Transdermal and transmucosal vortexed foam devices and the method of making.

이 특허를 인용한 특허 (15)

  1. Smith, Jeffrey B., Anti-viral compositions and methods of making and using the anti-viral compositions.
  2. Smith,Jeffrey B., Anti-viral compositions and methods of making and using the anti-viral compositions.
  3. Lin, Herbert Y.; Babitt, Jodie; Woolf, Clifford J.; Samad, Tarek A., Hemojuvelin fusion proteins and uses thereof.
  4. Cummins Joseph M., Low-dose oral administration of interferons.
  5. Frey, II,William H., Method for administering a cytokine to the central nervous system and the lymphatic system.
  6. Cummins, Joseph, Method for reducing injury and stabilizing muscle using orally administered interferon.
  7. Cho, Ho Sung; Daniel, Thomas O.; Hays Putnam, Anna-Maria A.; Wilson, Troy E., Modified human interferon polypeptides and their uses.
  8. Cho, Ho Sung; Daniel, Thomas O.; Hays, Anna-Maria; Wilson, Troy E., Modified human interferon polypeptides and their uses.
  9. Cho, Ho Sung; Daniel, Thomas O.; Hays, Anna-Maria A.; Wilson, Troy E., Modified human interferon polypeptides with at least one non-naturally encoded amino acid and their uses.
  10. Gantier, Rene; Vega, Manuel; Drittanti, Lila; Guyon, Thierry, Protease resistant modified interferon alpha polypeptides.
  11. Grimshaw,Michael N.; Barbieri,Donald J.; Vizzini,Louise M.; Marsh,Steve F., Rapidly disintegrable tablets.
  12. Grimshaw,Michael N.; Barbieri,Donald J.; Vizzini,Louise M.; Marsh,Steve F., Rapidly disintegrable tablets.
  13. Michael Gerard Tovey FR, Stimulation of host defense mechanisms against viral challenges.
  14. Jeffrey B. Smith, Zinc containing compositions for anti-viral use.
  15. Smith, Jeffrey B., Zinc containing compositions for anti-viral use.
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