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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0631751 (1996-04-10) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 408 인용 특허 : 0 |
An improved microfabricated apparatus for conducting a multiplicity of individual and simultaneous binding reactions is described. The apparatus comprises a substrate on which are located discrete and isolated sites for binding reactions. The apparatus is characterized by discrete and isolated regio
An improved microfabricated apparatus for conducting a multiplicity of individual and simultaneous binding reactions is described. The apparatus comprises a substrate on which are located discrete and isolated sites for binding reactions. The apparatus is characterized by discrete and isolated regions that extend through said substrate and terminate on a second surface thereof such that when a test sample is allowed to the substrate, it is capable of penetrating through each such region during the course of said binding reaction. The apparatus is especially useful for sequencing by hybridization of DNA molecules.
[ I claim:] [1.] A device for binding a target molecule, comprising:a substrate having oppositely facing first and second major surfaces;a multiplicity of discrete channels extending through said substrate from said first major surface to said second major surface;a first binding reagent immobilized
[ I claim:] [1.] A device for binding a target molecule, comprising:a substrate having oppositely facing first and second major surfaces;a multiplicity of discrete channels extending through said substrate from said first major surface to said second major surface;a first binding reagent immobilized on the walls of a first group of said channels, anda second binding reagent immobilized on the walls of a second group of said channels.
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