초록 ▼

Devices for the generation of inhalable aerosols by extrusion through a porous membrane by a motor-driven cam assembly are disclosed. The device holds a drug formulation container in a drug release position. The package is comprised of a collapsible wall with an opening and a cover for the opening t

Devices for the generation of inhalable aerosols by extrusion through a porous membrane by a motor-driven cam assembly are disclosed. The device holds a drug formulation container in a drug release position. The package is comprised of a collapsible wall with an opening and a cover for the opening that includes a porous membrane having a plurality of pores therein with a diameter in the range of 0.5 to 6.0 microns. An electric motor in the device is powered by a battery to rotate a cam assembly having three cams. The first cam forces a clamping member (configured to correspond to the outer periphery of the container) against the periphery of the collapsible wall of the container, sealing the jointure of the collapsible wall to the cover of the container along the entire periphery, except for a small unsealed portion thereof. The second cam crushes the collapsible wall, forcing the contents of the container through the unsealed portion of the jointure. The third cam operates to move the empty container out of the drug release position, while moving a new container into position.

대표청구항 ▼

[ What is claimed is:] [1.] A drug delivery device, comprising:a channel open at a first end for a patient to withdraw aerosolized formulation, the channel having an opening for receiving aerosolized formulation;an electric motor;a first cam shaft mechanically connected to the motor;a container hold

[ What is claimed is:] [1.] A drug delivery device, comprising:a channel open at a first end for a patient to withdraw aerosolized formulation, the channel having an opening for receiving aerosolized formulation;an electric motor;a first cam shaft mechanically connected to the motor;a container holding means for holding a container in an aerosol release position; andan extrusion cam connected to the first cam shaft, the extrusion cam configured such that upon rotation a surface is moved toward the drug release position.