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Method for reducing carryover contamination in an amplification procedure 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12P-019/34
  • C12Q-001/68
출원번호 US-0376762 (1995-01-23)
발명자 / 주소
  • Richards Rodney M.
  • Jones Theodore
  • Snitman David L.
  • Brown Gregory S.
출원인 / 주소
  • Amgen Inc.
대리인 / 주소
    Eggert
인용정보 피인용 횟수 : 41  인용 특허 : 3

초록

The present invention provides an efficient and economical method for reducing carryover contamination in an amplification procedure. The method of the present invention enables background caused by contaminant amplification product to be reduced or eliminated through the incorporation of at least o

대표청구항

[ What is claimed is:] [1.] A method for reducing DNA carryover contamination in a first test sample which may contain amplification product from a previously amplified DNA target-containing test sample comprising:(a) amplifying said DNA target of said previous test sample in the presence of at leas

이 특허에 인용된 특허 (3)

  1. Rashtchian Ayoub (Gaithersburg MD) Schuster David M. (Poolesville MD) Buchman ; III George W. (Mt. Airy MD), Method for altering a nucleotide sequence.
  2. Duck Peter (Ottawa CAX) Bender Robert (Ottawa CAX) Crosby William (Saskatoon CAX) Robertson John G. (L\Ange Gardien CAX), Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences.
  3. Mullis Kary B. (Kensington CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or-cloning nucleic acid sequences.

이 특허를 인용한 특허 (41)

  1. Kurn,Nurith, Amplification of RNA sequences using composite RNA-DNA primers and strand displacement.
  2. Armour, Christopher, Compositions and methods for directional nucleic acid amplification and sequencing.
  3. Armour, Christopher; Amorese, Doug; Li, Bin; Kurn, Nurith, Compositions and methods for negative selection of non-desired nucleic acid sequences.
  4. Amorese, Doug; Armour, Chris; Kurn, Nurith, Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation.
  5. Amorese, Doug; Armour, Chris; Kurn, Nurith, Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library regeneration.
  6. Kurn, Nurith, Compositions for amplification of RNA sequences using composite primers.
  7. Prakash, Indra; DuBois, Grant E., Condiments with high-potency sweetener.
  8. Kurn, Nurith; Wang, Shenglong, Global amplification using a randomly primed composite primer.
  9. Kurn, Nurith; Wang, Shenglong, Global amplification using a randomly primed composite primer.
  10. Kurn,Nurith; Wang,Shenglong, Global amplification using random priming by a composite primer.
  11. Connolly, Dennis Michael, High resolution DNA detection methods and devices.
  12. Dennis Michael Connolly, High resolution DNA detection methods and devices.
  13. Prakash, Indra; DuBois, Grant E., High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith.
  14. Kurn, Nurith; Wang, Shenglong, Isothermal nucleic acid amplification methods and compositions.
  15. Fu, Glenn K.; Shapero, Michael H.; Wang, Pei-Hua, Locus specific amplification using array probes.
  16. Achutharaman Vedapuram S. ; Swenberg Johanes, Method and apparatus for forming an epitaxial titanium silicide film by low pressure chemical vapor deposition.
  17. Braun, Erez; Eichen, Yoav; Sivan, Uri S, Method for gold deposition.
  18. Braun,Erez; Eichen,Yoav; Sivan,Uri, Method for gold deposition.
  19. Braun,Erez; Eichen,Yoav; Sivan,Uri S., Method for gold deposition.
  20. Kurn,Nurith, Methods and compositions for amplification of RNA sequences.
  21. Kurn, Nurith, Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers.
  22. Dutreix, Marie; Sun, Jian-Sheng; Biet, Elodie; Maurisse, Rosalie; Feugeas, Jean-Paul, Methods and compositions for effecting homologous recombination.
  23. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  24. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  25. Kurn, Nurith, Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof.
  26. Kurn, Nurith, Methods and compositions for linear isothermal amplification of polynucleotide sequences.
  27. Kurn Nurith, Methods and compositions for linear isothermal amplification of polynucleotide sequences, using a RNA-DNA composite primer.
  28. Kurn, Nurith, Methods and compositions for transcription-based nucleic acid amplification.
  29. Kurn, Nurith, Methods and compositions for transcription-based nucleic acid amplification.
  30. Kurn,Nurith, Methods and compositions for transcription-based nucleic acid amplification.
  31. Kurn,Nurith, Methods and kits for amplification of RNA sequences using composite primers.
  32. Kurn, Nurith, Methods and probes for detection and/or quantification of nucleic acid sequences.
  33. Kurn, Nurith; Dafforn, Geoffrey A., Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids.
  34. Kurn,Nurith; Wang,Martin Junhong, Methods for generating double stranded DNA comprising a 3' single stranded portion and uses of these complexes for recombination.
  35. Kurn, Nurith, Methods of RNA amplification in the presence of DNA.
  36. Kurn, Nurith, Methods, kits and compositions for single primer linear isothermal amplification of nucleic acid sequences.
  37. Braun, Erez; Eichen, Yoav; Sivan, Uri; Ben-Joseph, Gdalyahu, Microelectronic components and electronic networks comprising DNA.
  38. Kurn, Nurith; Wang, Shenglong, Nucleic acid amplification procedure using RNA and DNA composite primers.
  39. Schroeder, Benjamin G., Reduced representation bisulfite sequencing with diversity adaptors.
  40. Amorese, Doug; Schroeder, Benjamin G.; Scolnick, Jonathan, Sequential sequencing.
  41. Landegren, Ulf, Ultrasensitive immunoassays.
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