초록 ▼

Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each time is consistent. A device for de

Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each time is consistent. A device for delivering insulin by inhalation is disclosed which device comprises a means for measuring inhaled volume and for halting inhalation at a pre-determined point. The device also comprises an adjustable means for applying various amounts of force to a container of formulation to expel different amounts of drug from the container based on the force applied.

대표청구항 ▼

[ We claim:] [1.] A method of administering insulin to a human patient by inhalation, comprising:(a) exhaling a determined volume of air;(b) aerosolizing an insulin formulation;(c) inhaling the aerosolized formulation with a determined volume of air; and(d) repeating (a), (b) and (c) a plurality of

[ We claim:] [1.] A method of administering insulin to a human patient by inhalation, comprising:(a) exhaling a determined volume of air;(b) aerosolizing an insulin formulation;(c) inhaling the aerosolized formulation with a determined volume of air; and(d) repeating (a), (b) and (c) a plurality of times wherein the determined volume of air exhaled in (a) is substantially the same for each step (a) and the determined volume of air in (c) is substantially the same for each step (c).