초록 ▼

Granules of starch or low protein rice flour are agglomerated to a larger size and a spherical shape by combining the granules with silicon dioxide and water to form a slurry, and drying the slurry by a spray dryer. The agglomerates have better flowability than the granules, and are readily used as

Granules of starch or low protein rice flour are agglomerated to a larger size and a spherical shape by combining the granules with silicon dioxide and water to form a slurry, and drying the slurry by a spray dryer. The agglomerates have better flowability than the granules, and are readily used as direct compression fillers for tablets and capsules in drug or nutrient formulations. Tablets formed from these agglomerates have good hardness and friability, as well as favorable disintegration and dissolution characteristics. Chemically or physically modified starches can also be used, and starches other than rice starches can be included as well.

대표청구항

[ We claim:] [1.] Agglomerates comprising 40% to 95% of a member selected from the group consisting of rice starch, 0.2-5.0%-protein rice flour, and a combination thereof, 0.1% to 50% silicon dioxide, and 1% to 15% water, and formed by spray drying or by drying a slurry.

[ We claim:] [1.] Agglomerates comprising 40% to 95% of a member selected from the group consisting of rice starch, 0.2-5.0%-protein rice flour, and a combination thereof, 0.1% to 50% silicon dioxide, and 1% to 15% water, and formed by spray drying or by drying a slurry.