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[미국특허] Peptide/protein suspending formulations 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
  • A61K-009/50
  • A61K-038/21
  • C07K-014/52
출원번호 US-0475238 (1995-06-07)
발명자 / 주소
  • Eckenhoff
  • deceased James B.
  • Holladay Leslie A.
  • Leonard
  • Jr. John Joseph
  • Leung Iris K. M.
  • Tao Sally A.
  • Magruder Judy A.
  • Carr John P.
  • Wright Jeremy
출원인 / 주소
  • ALZA Corporation
대리인 / 주소
    Clarke
인용정보 피인용 횟수 : 92  인용 특허 : 34

초록 ▼

The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5% by weight beneficial agent and having a viscosity and be

대표청구항 ▼

[ What is claimed is:] [1.] A beneficial agent formulation for use in a device which delivers the formulation over an extended delivery period, the formulation comprising:(a) at least 5% by weight beneficial agent in the form of solid particles, the beneficial agent particle size being 0.3 to 50 mic

이 특허에 인용된 특허 (34) 인용/피인용 타임라인 분석

  1. Bichon Daniel (Gaillard FRX), Biodegradable polypeptide and its use for the gradual release of drugs.
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  2. Kwan Henry K. H. (Summit NJ), Biologically stable interferon compositions comprising thimerosal.
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  4. Churchill Jeffrey R. (Northwich GBX) Hutchinson Francis G. (Lymm GBX), Continuous release formulations.
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  5. Churchill Jeffrey R. (Northwich GBX) Hutchinson Francis G. (Lymm GBX), Continuous release formulations.
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  6. Elger Gordon (Huntingdon GBX) Leslie Stewart T. (Cambridge GBX) Malkowska Sandra T. A. (Landbeach GBX) Miller Ronald B. (Basel CHX) Neale Philip J. (Harston GBX), Controlled release pharmaceutical composition.
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  7. Eckenhoff James B. (Los Altos CA), Delivery device providing beneficial agent stability.
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  8. Magruder Judy A. (Mt. View CA) Eckenhoff James B. (Los Altos CA) Cortese Richard (Los Gatos CA) Wright Jeremy C. (Los Altos CA) Peery John R. (Palo Alto CA), Delivery system comprising means for delivering agent to livestock.
    상세보기
  9. Magruder Judy A. (Mt. View CA) Eckenhoff James B. (Los Altos CA) Cortese Richard (Los Gatos CA) Wright Jeremy C. (Los Altos CA) Perry John R. (Palo Alto CA), Delivery system for beneficial agent over a broad range of rates.
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  10. Wong Patrick S. L. (Palo Alto CA) Pharriss Bruce B. (Palo Alto CA), Delivery system with mated members for storing and releasing a plurality of beneficial agents.
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  11. Eckenhoff James B. (Los Altos CA) Magruder Judy A. (Mt. View CA) Cortese Richard (Cupertino CA) Peery John R. (Palo Alto CA) Wright Jeremy C. (Los Altos CA), Device comprising means for protecting and dispensing fluid sensitive medicament.
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  12. Magruder Judy A. (Mt. View CA) Eckenhoff James B. (Los Altos CA) Cortese Richard (Los Gatos CA) Wright Jeremy C. (Los Altos CA) Peery John R. (Palo Alto CA), Dispenser for increasing feed conversion of hog.
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  13. Orth Jeffrey L. (Salt Lake City UT) Hoffer Richard E. (Park City UT) Triolo Philip M. (Salt Lake City UT), Implantable structure for containing substances for delivery to a body.
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  17. Yim Zachary (Paramus NJ) Zupon Martin (Basking Ridge NJ) Chaudry Imtiaz (Denville NJ), Insoluble copper-alpha interferon complex.
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  18. Asculai Samuel S. (East Meadow NY) Rapp Fred (Hershey PA), Interferon-containing compositions.
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  19. Buirge Andrew W., Intravascular stent pump.
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  20. Orbn Erno (Budapest HUX) Balogh Tibor (Budapest HUX) Ila Lajos (Budapest HUX) Ambrus Gbor (Budapest HUX) Jekkel Antnia (Budapest HUX) Elek Sndor (Budapest HUX) Tomori va (Budapest HUX) Elekes Istvn (, Intravenous pharmaceutical composition and process for preparing the same.
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  21. Wong Patrick S. L. (Palo Alto CA), Osmotic device with delayed activation of drug delivery.
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  22. Himmelstein Kenneth J. (Lawrence KS), Osmotic drug delivery system.
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  24. Lattanzi Filippo (Siena ITX) Vanni Riccardo (Siena ITX), Pharmaceutical composition for intrarectal administration of a calcitonin and unit dosage forms prepared therefrom.
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  26. Saffran Murray (Toledo OH) Neckers Douglas C. (Perrysburg OH), Polymers containing cross-linked azo bonds, which polymers are useful for releasing therapeutic agents into the lower ga.
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  29. Stewart ; II William E. (Lewisville TX), Stabilization of human interferon.
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  31. Murakami Masuo (Tokyo JA) Kawahara Shigemi (Higashikurume JA) Kawata Hiroitsu (Kawagoe JA) Okazaki Kiyoshi (Kawagoe JA) Sekino Jun (Kashiwa JA) Shimizu Hidemi (Ageo JA), Stable prostaglandin E group-containing formulation.
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  32. Battersby John E. (So. San Francisco CA) Clark Ross G. (Pacifica CA) Hancock William S. (Hillsborough CA), Sustained release pharmaceutical composition.
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  34. Wong Patrick S. (Palo Alto CA), Vaginal contraceptive system made from block copolymer.
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  3. Leung, Karling Alice, Compositions, devices and methods of use thereof for the treatment of cancers.
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