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Antioxidant preparation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-047/00
  • A61K-009/68
  • A61K-009/28
  • A61K-009/44
출원번호 US-0982058 (1997-12-01)
발명자 / 주소
  • Hersh Theodore
출원인 / 주소
  • Thione International, Inc.
대리인 / 주소
    Wittenberg
인용정보 피인용 횟수 : 64  인용 특허 : 48

초록

A composition for reducing free radical damage induced by tobacco products and environmental pollutants. The composition includes reduced glutathione and a source of selenium. The composition can be administered orally in the form of a gel, lozenge, tablet or gum.

대표청구항

[ I claim:] [1.] A composition for reducing free radical damage induced by tobacco products and environmental pollutants comprising, as active ingredients, reduced glutathione and a source of selenium selected from the group consisting of elemental selenium, selenomethionine and selenocysteine, said

이 특허에 인용된 특허 (48)

  1. N\Guyen Quang L. (Antony FRX) Griat Jacqueline (Ablon FRX) Millecamps Francois (Paris FRX), Antioxidant system based on an ascorbyl ester in combination with a complexing agent and a thiol and to compositions con.
  2. Paul Stephen M. (Rancha Santa Margarita CA), Ascorbic acid compositions providing enhanced human immune system activity.
  3. Neigut Stanley J. (10 Red Rowan La. Plymouth Meeting PA 19462), Composition for the topical treatment of skin damage.
  4. Yeh Kuo-Chen (Westfield NJ) Sena Frank J. (Brooklyn NY) Alfano Michael C. (Franklin Lakes NJ), Compositions and method for the treatment of disease.
  5. Levin Robert H. (11127 Jardin Pl. Cincinnati OH 45241), Compositions containing LYCD and other topically active medicinal ingredients.
  6. Powell Maxwell M. (Great Neck NY), Compositions suitable for human topical application including a growth factor and/or related materials.
  7. Spector Abraham (New York NY) Wilson Stephen R. (Chatham NJ) Zucker Paul A. (Maplewood NJ), Compounds having glutathione peroxidase activity and use thereof.
  8. McCook John P. (Guilford CT) Meyers Alan J. (Trumbull CT) Dobkowski Brian J. (Milford CT) Burger Allan R. (Passaic NJ), Cosmetic sunscreen composition containing green tea and a sunscreen.
  9. N\Guyen Quang L. (Antony FRX) Junino Alex (Livry-Gargan FRX) Colin Christian (Paris FRX) Lindenbaum Albert (Versailles FRX) Loufrani Catherine (Le Perreux Sur Marne FRX), Dermatological glutathione alkyl ester composition and a process for topical treatment.
  10. Tamabuchi Hiroshi (Takatsuki JPX), Emulsion cosmetic stably containing vitamin C.
  11. Trowbridge Ian S. (San Diego CA) Taetle Raymond (Tucson AZ) White Suhaila N. (Poway CA), Enhanced inhibition of tumor cell proliferation using a combination of two monoclonal antibodies to the human transferri.
  12. Cavazza Claudio (Rome ITX) Cavazza Paolo (Rome ITX), Esters of L-carnitine and acyl L-carnitine with hydoxy acids for producing pharmcaeutical compositions for treating derm.
  13. Cavazza Claudio (Rome ITX) Cavazza Paolo (Rome ITX), Esters of L-carnitine and alkanoyl L-carnitines with glycolic acid or esters thereof and pharmaceutical compositions con.
  14. Tinti Maria O. (Rome ITX) Quaresima Emma (Rome ITX) Bagolini Carlo (Rome ITX) deWitt Paolo (Rome ITX), Esters of mercapto acyl-carnitines and pharmaceutical compositions containing same.
  15. Finkenaur Amy L. (Somerville NJ) Cohen Jonathan M. (Marlboro NJ) Shalaby Shalaby W. (Lebanon NJ) Sandoval Elisabeth A. (Irvine CA) Bezwada Rao S. (Whitehouse Station NJ) Kronenthal Richard L. (Fairla, Gel formulations containing growth factors and acrylamide polymer.
  16. Meister Alton (New York NY), Glutathione delivery system.
  17. Grisar J. Martin (Wissembourg FRX) Petty Margaret A. (Strasbourg FRX) Bolkenius Frank (Kehl DEX), Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans.
  18. Noble Mark David,GB2 ; Mayer Margot,GB2, Intracellular glutathione raising agents for therapeutic treatments.
  19. Tinti Maria O. (Rome ITX) Quaresima Emma (Casal Palocco ITX) Bagolini Carlo (Rome ITX) DeWitt Paolo (Rome ITX), Mercapto acyl-carnitines and pharmaceutical compositions containing same.
  20. Burke Karen E. (420 E. 51st New York NY 10022), Method for the prevention and reversal of the extrinsic aging of the skin by transdermal application of selenamino acids.
  21. Perricone Nicholas V. (350 Cosey Beach Ave. East Haven CT 06512), Method for treating and preventing sunburn and sunburn damage to the skin.
  22. Voyt Walter F. (Rte. 1 ; Box 43 Elwood IL 60421), Method of and composition for preventing sunburn while affording tanning.
  23. Bar-Shalom Daniel,DKX ; Bukh Niels,DKX ; Hamburger Jesper,DKX, Method of treating conditions of teeth and their supporting tissue.
  24. Ballagh Robert H. (125 Bell Farm Rd. Suite 203 Barrie ; Ontario CAX L4M 6L2) Jones Jeff B. (217 Pembroke Street East Pembroke ; Ontario CAX K8A 3J8), Method of treating tumour cells using catalase.
  25. Matsubara Junko (c/o Department of Epidemiology ; School of Medicine ; University of Tokyo ; No. 3-1 ; Hongo 7-chome Bunkyo-Ku ; Tokyo 113 JPX), Method of using manganese to protect an animal from radiation damage.
  26. Gabrilove Janice L. (New York NY), Methods for prevention and treatment of mucositis with granulocyte colony stimulating factor.
  27. Ippolito Ferdinando (Rome ITX) Passi Siro (Rome ITX), Methods for the treatment of seborrheic dermatitis.
  28. Bissett Donald Lynn, Methods of using 2,4-dienoic acid esters of tocopherols to reduce free radical damage in mammalian cells.
  29. Piazza Gary A. (West Chester OH) Mazur Adam W. (Cincinnati OH), Methods of using lysophosphatidic acid for treating hyperproliferative conditions.
  30. Shanklin ; Jr. James R. (Richmond VA), N-(aryl-,aryloxy-,arylthio-arylsulfinyl-and arylsulfonyl-)alkyl-N,N′-(or n′n′)alkylaminoalkyl ureas and cyanoguanidin.
  31. Allen Larry M. (Denver CO), Pharmaceutical vehicles for exhancing penetration and retention in the skin.
  32. de Rigal Jean (Claye Souilly FRX) Leveque Jean-Luc (Le Raincy FRX) Contamin Jean-Claude (Cantaron FRX) Aubert Lucien (Cap d\Ail FRX), Photoprotective/cosmetic compositions comprising antioxidants and filamentous bacterial extracts.
  33. Dubur Gunar Y. (Riga SUX) Biseniex Egils A. (Riga SUX) Uldrikis Yan R. (Elgava SUX) Ivanov Evgeny V. (Leningrad SUX) Ponomareva Tatyana V. (Leningrad SUX) Merkushev Gennady N. (Leningrad SUX) Yakubov, Preparation for preventing and treatment of skin radiation burn lesions.
  34. Kalopissis ; Gregoire ; Jacquet ; Bernard ; Lang ; Gerard, Protecting skin and hair with cosmetic compositions containing superoxide dismutase.
  35. Otsu Yoshiro (Minoo JPX) Arima Yaeno (Kobe JPX) Nakajima Katsuyuki (Maebashi JPX) Adachi Masakazu (Takasaki JPX) Muramatsu Tsutomu (Nara JPX) Hanada Katsumi (Hirosaki JPX), Remedy for dermatopathy and metallothionein inducer.
  36. Cavazza Claudio (Rome ITX), Salts of-carnitine and alkanoyl L-carnitines and process for preparing same.
  37. Shapira Niva (5 K Zitomir Tel-Aviv ILX), Sun-exposure nutritional supporting composition.
  38. Hubaud Jean-Claude (Gap FRX) Thiry Daniele (La Turbie FRX), Suntan accelerator composition.
  39. Malfroy-Camine Bernard (Arlington MA) Doctrow Susan Robin (Roslindale MA), Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease.
  40. Pawelek John (Hamden CT) Osber Michael P. (Hamden CT) Orlow Seth J. (Long Island City NY), Synthetic melanin as a sunscreen and tanning agent.
  41. Okuyama Shinichi (Miyagi JPX) Mishina Hitoshi (Miyagi JPX) Furuse Kazumaro (Tokyo JPX) Murotani Isao (Kanagawa JPX), Therapeutic method for treating radiation ulcers.
  42. Cavazza Claudio (Rome ITX) Cavazza Paolo (Rome ITX), Therapeutical method for the treatment of dermatoses using O-esters of L-carnitine.
  43. Winter Susan C. (Fresno CA) Szabo-Aczel Stefan (Clovis CA), Topical L-carnitine composition.
  44. Burke Karen E. (515 E. 89th St. New York NY 10028) Calvo Luis C. (8 Avon Pl. Bayshore NY 11708), Topical compositions containing selenoamino acids for the prevention of ultraviolet radiation-induced skin damage.
  45. Mitchnick Mark (Wainscott NY) Muhammed Mamoun (Djursholm SEX), Topical ultra-violet radiation protectants.
  46. Van Scott Eugene J. (1138 Sewell La. Rydal PA 19046) Yu Ruey J. (4 Lindenwold Ave. Ambler PA 19002), Treatment of disturbed keratinization.
  47. Hersh Theodore (Atlanta GA) Warshaw Michael A. (Savannah GA), X-ray induced skin damage protective composition.
  48. Levin Robert H. (11127 Jardin Pl. Cincinnati OH 45241) Keller Stephen J. (1334 Edwards Rd. Cincinnati OH 45208), Yeast-derived epidermal growth factor/urogastrone-like products.

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  3. Hersh Theodore, Antioxidant composition for the treatment of psoriasis and related diseases.
  4. Theodore Hersh ; Rebecca Hersh, Antioxidants to neutralize tobacco free radicals.
  5. Henry T. Tyrpin ; Michael P. Russell ; David L. Witkewitz ; Sonya S. Johnson ; Ronald L. Ream ; Christine L. Corriveau, Caffeine coated chewing gum product and process of making.
  6. Barreca, Jack, Chewing gum.
  7. Barreca, Jack, Chewing gum with B vitamins.
  8. Barreca, Jack; Kovarik, Joseph E., Chewing gum with tomatidine.
  9. Johnson,Sonya S.; Barkalow,David G.; Greenberg,Michael J.; Sheldon,Gloria T., Coated chewing gum product and method of making.
  10. Zyck, Daniel J.; Greenberg, Michael J.; Barkalow, David G.; Marske, Scott W.; Schnell, Philip G.; Mazzone, Philip; Witkewitz, David L., Coated chewing gum products containing an acid blocker and process of preparing.
  11. Zyck, Daniel J.; Greenberg, Michael J.; Barkalow, David G.; Marske, Scott W.; Schnell, Philip G.; Mazzone, Philip; Hammond, John E.; Witkewitz, David L.; Sitler, Daniel J.; Petrocelli, Raynold M., Coated chewing gum products containing an antigas agent.
  12. Zyck, Daniel J.; Greenberg, Michael J.; Barkalow, David G.; Marske, Scott W.; Schnell, Philip G.; Mazzone, Philip, Coated chewing gum products containing antacid and method of making.
  13. Davis,Richard; Howell,Howard L., Composition and methods for improving retinal health.
  14. Diaz, Victor H., Composition including superoxide dismutase and prickly-pear cactus for minimizing and preventing hangovers.
  15. Prencipe, Michael; Robinson, Richard Scott; Kohli, Rajnish; Sullivan, Richard J.; Cummins, Diane, Compositions and devices.
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  17. Kohli, Rajnish; Fontana, Jose Eder, Dental floss.
  18. Reznick, Abraham Z.; Nagler, Rafael M.; Klein, Ifat, Filters for preventing or reducing tobacco smoke-associated injury in the aerodigestive tract of a subject.
  19. Suovaniemi, Osmo; Salaspuro, Mikko; Salaspuro, Ville; Marvola, Martti, Food composition for binding acetaldehyde in mouth and in digestive track, and method for the preparation of the composition.
  20. Yang, BaoKang; Martinez, Sarah B., Fortified confectionery delivery systems and methods of preparation thereof.
  21. Bar-Or, David, Metal-binding compounds and uses therefor.
  22. Bar-Or, David, Metal-binding compounds and uses therefor.
  23. Bar-Or, David, Metal-binding compounds and uses therefor.
  24. Bar-Or, David; Curtis, C. Gerald; Lau, Edward; Rao, Nagaraja K. R.; Winkler, James V.; Crook, Wannell M., Metal-binding compounds and uses therefor.
  25. Petrus, Edward J., Method and compositions for treatment of the aging eye.
  26. Salaspuro, Mikko; Marvola, Martti, Method and preparation for binding acetaldehyde in saliva, stomach and large intestine.
  27. Zyck, Daniel J.; Sitler, Daniel J.; Barkalow, David G.; Knutsen, Jonathan J.; Shen, Chungsea A.; Zuehlke, Julius W.; Schnell, Philip G., Method for making coated chewing gum products including a high-intensity sweetener.
  28. Witkewitz,David L.; Barkalow,David G.; Knutsen,Jonathan J.; Shen,Chungsea A.; Zuehlke,Julius W.; Yatka,Robert J., Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener.
  29. Zyck, Daniel J.; Greenberg, Michael J.; Barkalow, David G.; Marske, Scott W.; Schnell, Philip G.; Mazzone, Philip, Method of making coated chewing gum products containing various antacids.
  30. Johnson, Sonya S.; Record, David W.; Greenberg, Michael J.; Reed, Michael A.; Gudas, Victor V.; Schnell, Philip G.; Seielstad, Donald A.; Tyrpin, Henry T.; Russell, Michael P.; Witkewitz, David L.; S, Method of producing active agent coated chewing gum products.
  31. Morehouse, Scott, Method of treating ear infections.
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  33. Garcia, Joaquin Bautista; Cabanas, Robin S.; Josias, Wilbens; Wu, Donghui, Methods for production of arginine biocarbonate at low pressure.
  34. Wu, Donghui, Methods for production of high concentration of arginine bicarbonate solution at high pressure.
  35. Kohli, Rajnish; Robinson, Richard Scott; Wu, Donghui; Josias, Wilbens, Methods for salt production.
  36. Prasad, Kedar N; Haase, Gerald M, Multiple antioxidant micronutrients.
  37. McGrew, Gordon N.; Barkalow, David G.; Johnson, Sonya S.; Record, David W.; Patel, Mansukh M.; Nimz, Jack D.; Zibell, Steven E.; Yatka, Robert J.; Greenberg, Michael J.; Aumann, Rebecca A.; Zyck, Dan, Nutraceuticals or nutritional supplements and method of making.
  38. Stillman,Suzanne Jaffe, Nutritionally fortified liquid composition with added value delivery systems/elements/additives.
  39. Sullivan, Richard Scott; Hu, Yanan; Du-Thumm, Laurence; Lavender, Stacey; Santarpia, III, Ralph Peter; Liu, Zhiqiang, Oral care methods and systems.
  40. Kohli, Rajnish; Robinson, Richard Scott; Leite, Sergio; Simon, Eric A.; Sullivan, Richard J.; Santarpia, III, Ralph Peter; Prencipe, Michael; Subramanyam, Ravi; Mello, Sarita V.; Wu, Donghui; Chopra, Suman; Morgan, Andre M.; Cummins, Diane; Zaidel, Lynette; Wang, Qin; Tambs, Gary Edward; Barnes, Virginia Monsul, Oral care product and methods of use and manufacture thereof.
  41. Prencipe, Michael; Cummins, Diane; Robinson, Richard Scott; Mello, Sarita V.; Sullivan, Richard J.; Chopra, Suman; DePierro, Karen J.; Zaidel, Lynette; Christopoulou, Constantina; Subramanyam, Ravi; Wu, Donghui; Morgan, Andre M.; Santarpia, III, Ralph Peter; Wang, Qin; Tambs, Gary Edward; Kohli, Rajnish; Barnes, Virginia Monsul; Leite, Sergio; Simon, Eric A., Oral care product and methods of use and manufacture thereof.
  42. Prencipe, Michael; Van Rycke, Isabelle; Lovell, Richard, Oral care regimen.
  43. Ream, Ronald L.; Greenberg, Michael J.; Wokas, William J.; Corriveau, Christine L., Over-coated chewing gum formulations.
  44. Ronald L. Ream ; Michael J. Greenberg ; William J. Wokas ; Christine L. Corriveau, Over-coated chewing gum formulations.
  45. Ronald L. Ream ; Michael J. Greenberg ; William J. Wokas ; Christine L. Corriveau, Over-coated chewing gum formulations.
  46. Ream Ronald L. ; Corriveau Christine L. ; Graff Gwendolyn ; Matulewicz Leonard, Over-coated chewing gum formulations including tableted center.
  47. Ream Ronald L. ; Corriveau Christine L. ; Graff Gwendolyn ; Matulewicz Leonard, Over-coated chewing gum formulations including tableted center.
  48. Song, Joo H.; Townsend, Donald J.; Record, David W.; Tyrpin, Henry T.; Russell, Michael P.; Schnell, Philip G.; Ream, Ronald L.; Corriveau, Christine L., Process for controlling release of active agents from a chewing gum coating and product thereof.
  49. Yang, BaoKang; Martinez, Sarah B., Process for promoting calcium absorption.
  50. Gmunder, Charlean B.; Li, Weisheng; Ream, Ronald L, Sildenafil citrate chewing gum formulations and methods of using the same.
  51. Gmunder, Charlean B.; Li, Weisheng; Ream, Ronald L., Sildenafil citrate chewing gum formulations and methods of using the same.
  52. Cole,Curtis A.; Flack,Laura E.; Kaminski,Claudia; Van Leeuwen,Victoria; Lukenbach,Elvin R., Skin care composition.
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  56. Tricca, Robert E.; Wu, Benjamin M.; Li, Chunhua; Kuo, Eric, Systems and methods for intra-oral diagnosis.
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  58. Li, Chunhua; Carlyle, Wenda C.; De Smedt, Philippe; Abolfathi, Amir; Kuo, Eric E.; Tricca, Robert E.; Chen, Jennifer C.; Wu, Benjamin M., Systems and methods for intra-oral drug delivery.
  59. Mello, Sarita V.; Arvanitidou, Evangelia, Therapeutic oral composition.
  60. Prasad,Kedar N.; Haase,Gerald M.; Cole,William C., Use of multiple antioxidant micronutrients as systemic biological radioprotective agents against potential ionizing radiation risks.
  61. Stillman, Suzanne Jaffe, Water containing soluble fiber.
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