[특허]High concentration white cells, a method for agglomeration of the high concentration and a bag set for use in conjuncti

[미국특허] High concentration white cells, a method for agglomeration of the high concentration and a bag set for use in conjuncti 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61B-019/00 B01D-033/15
출원번호	US-0128208 (1998-08-03)
발명자 / 주소	Rubinstein Pablo Coelho Philip Henry Stevens Cladd E.
출원인 / 주소	New York Blood Center, Inc.
대리인 / 주소	Amster, Rothstein & Ebenstein
인용정보	피인용 횟수 : 88 인용 특허 : 9

초록 ▼

A therapeutic product formed from a high concentration of white blood cells having a high degree of cell viability. The white blood cells are sequestered from their normal population presence in whole blood by placing the blood into a container and preventing coagulation of the blood, separating the blood into two components, one of which is extremely rich in white blood cells through the use of a reagent and centrifugation, sequestering the white cell concentration, and freezing the white cells.

대표청구항 ▼

[ I claim:] [1.] A system for concentrating blood cells, comprising:a first bag for containing blood and an anticoagulant,a container, removably coupled to said first bag through a coupling system, for containing a red blood cell sedimentation reagent,a second bag removably coupled to said first bag through a coupling system for receiving from said first bag a first supernatant containing at least 80% of white blood cells contained in said first bag after said blood is mixed with said red blood cell sedimentation reagent, and after said first bag is centrifuged at a speed sufficient to obtain said first supernatant and a first sediment containing at least 90% of said red blood cells contained in said first bag,a third bag removably coupled to said second bag through a coupling system for receiving from said second bag all or a portion of a second supernatant contained in said second bag after said second bag is centrifuged at a speed sufficient to obtain a second supernatant and a second sediment, anda freezer bag removably coupled to said second bag through a coupling system for receiving from said second bag a resulting composition remaining after transfer of said all or a portion of said second supernatant to said third bag, said resulting composition including at least 80% of white blood cells contained in said blood and less than all of plasma contained in said blood.

이 특허에 인용된 특허 (9) 인용/피인용 타임라인 분석

Shiraki Hiroshi (Chikushino JPX) Yamamoto Kiyoko (Chikushino JPX) Kitagawa Akiko (Mito JPX) Kawaoka Tatsuhiko (Fujinomiya JPX) Oonaka Yukihiro (Fuji JPX), Apparatus for separation of blood components.
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Joie Michel,BEX ; Debrauwere Jack,BEX ; Bernes Jean-Claude,BEX ; Goldhaber Richard, Blood collection container.
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Carmen Raleigh A. ; Chong Chi Yong ; Garcez Randy B., Long-term blood components storage system and method.
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Rubinstein Pablo ; Coelho Philip Henry ; Stevens Cladd E., Method for concentrating white cells from whole blood by adding a red cell sedimentation reagent to whole anticoagulate.
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Joie Michel (Ernage BEX) Debrauwere Jack (Halle BEX) Bernes Jean-Claude (Faimes BEX), Method for storing blood in a container having multiple chambers.
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Tanokura Nobukazu (Shizuoka JPX) Ohnaka Yukihiro (Shizuoka JPX) Ishida Noboru (Shizuoka JPX), Method for treatment of blood using a blood bag.
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Carmen Raleigh A. (Concord CA) Nelson Edward J. (San Rafael CA), Pre-storage filtration of platelets.
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Goldhaber Richard (Lake Forest IL) Bischof Daniel F. (McHenry IL), Systems and methods for removing undesired matter from blood cells.
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[미국특허] High concentration white cells, a method for agglomeration of the high concentration and a bag set for use in conjuncti 원문보기

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[미국특허] High concentration white cells, a method for agglomeration of the high concentration and a bag set for use in conjuncti 원문보기

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