초록 ▼

A wearable peritoneal dialysis device providing continuous removal of waste metabolites from the blood using a small volume (250-1000 mls) of protein-containing dialysate having an overall flow rate of about 2-3 liters per hour. The device may be worn in several places on the torso and limbs. Includ

A wearable peritoneal dialysis device providing continuous removal of waste metabolites from the blood using a small volume (250-1000 mls) of protein-containing dialysate having an overall flow rate of about 2-3 liters per hour. The device may be worn in several places on the torso and limbs. Included are methods for peritoneal dialysis having improved efficiency, as well as methods for providing hormones, nutrients or therapeutic agents to a patient.

대표청구항 ▼

[ What is claimed is:] [1.] A method for the continuous removal of protein-bound uremic toxins from the blood which enters the peritoneal cavity of a patient, comprising the steps of:a) introducing from about 250 to about 1000 ml of dialysate into the peritoneal cavity, wherein protein-bound uremic

[ What is claimed is:] [1.] A method for the continuous removal of protein-bound uremic toxins from the blood which enters the peritoneal cavity of a patient, comprising the steps of:a) introducing from about 250 to about 1000 ml of dialysate into the peritoneal cavity, wherein protein-bound uremic toxins from the blood translocate into said dialysate;b) removing the used dialysate from said peritoneal cavity;c) separating the used dialysate through a filter into a protein-containing fraction and an ultrafiltrate fraction;d) treating said ultrafiltrate fraction to remove waste products present in said ultrafiltrate fraction, thereby generating a purified ultrafiltrate fraction;e) treating said protein-containing fraction from said filter to remove undesirable proteins and noxious uremic substances bound to proteins, thereby generating detoxified proteins;f) combining said detoxified proteins and purified ultrafiltrate fraction to from regenerated dialysate;g) reintroducing said regenerated dialysate into the peritoneal cavity.