초록 ▼

The invention provides compositions and methods for generating new tissue on a surface, e.g., a surface of damaged or lost tissue, of a structure or organ in a mammal, The methods involve applying a thin layer of a liquid hydrogel-cell composition to the surface; and allowing the liquid hydrogel-cel

The invention provides compositions and methods for generating new tissue on a surface, e.g., a surface of damaged or lost tissue, of a structure or organ in a mammal, The methods involve applying a thin layer of a liquid hydrogel-cell composition to the surface; and allowing the liquid hydrogel-cell composition to solidify, thereby forming a matrix that enables the tissue precursor cells to grow and generate new tissue. The surface can be internal, e.g., the surface of an organ or the internal surface of a blood vessel, or external, e.g., skin.

대표청구항 ▼

[ I claim:] [1.] A method for generataing new living tissue on and external surface of a tissue structure or organ in a mammal, said method comprising:a) obtaining a liquid hydrogel-cell composition comprising a hydrogel and live tissue precursor cells;b) applying a thin layer of said liquid hydroge

[ I claim:] [1.] A method for generataing new living tissue on and external surface of a tissue structure or organ in a mammal, said method comprising:a) obtaining a liquid hydrogel-cell composition comprising a hydrogel and live tissue precursor cells;b) applying a thin layer of said liquid hydrogel-cell composition to the external surface in the mammal; andc) allowing said applied liquid hydrogel-cell composition to solidify, thereby forming a matrix that enables the tissue precursor cells to grow and generate new living tissue.