초록 ▼

A method for separating cells is presented. The method provides a flow through fractional cell sorting process that is based on the application of a magnetic force to cells having a range of magnetic labeling densities. Magnetically labeled cells are introduced into a flow channel. The cells are con

A method for separating cells is presented. The method provides a flow through fractional cell sorting process that is based on the application of a magnetic force to cells having a range of magnetic labeling densities. Magnetically labeled cells are introduced into a flow channel. The cells are continuously fractionated into flow streams based on magnetic susceptibility by subjecting the cells in the flow channel to a magnetic field. The fractionated cells are recovered based on their response to the magnetic field. Methods employing dipole fractional sorters and quadrapole annular sorters are also presented.

대표청구항 ▼

[ We claim:] [1.] A method for separating a heterogeneous particle population wherein the heterogeneity is based on magnetic susceptibility, the method comprising the steps of:introducing the heterogeneous particle population into an essentially laminar flow stream;continuously fractionating said he

[ We claim:] [1.] A method for separating a heterogeneous particle population wherein the heterogeneity is based on magnetic susceptibility, the method comprising the steps of:introducing the heterogeneous particle population into an essentially laminar flow stream;continuously fractionating said heterogeneous particle population in said flow stream into fractionated sample flow streams based on magnetic susceptibility by subjecting said heterogeneous particle population to a magnetic field having predetermined field characteristics for the purpose of generating at least two flow compartments;recovering at least a portion of said heterogeneous particle population by selecting portions of said fractionated sample flow streams for recovery according to said predetermined magnetic field characteristics.