초록 ▼

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be app

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.

대표청구항 ▼

[ I claim:] [1.] A mixing head suitable for attachment to and use with a supply device for application of a mixture of two separate components to a surface, which mixing head comprisesa housing;contained in said housing, a branched channel which connects two entry ports of said channel through separ

[ I claim:] [1.] A mixing head suitable for attachment to and use with a supply device for application of a mixture of two separate components to a surface, which mixing head comprisesa housing;contained in said housing, a branched channel which connects two entry ports of said channel through separated portions of said channel to a common portion of said channel which provides a single exit port of said channel;said entry ports adapted for attachment to separate means in said device for dispensing each of said separate components, so as to permit each component to flow through said entry ports into said channel wherein said channel is further configured so that the components flow into said common portion of said channel and form a mixture, which mixture flows through said exit port; andan unbranched channel adjacent to said branched channel, said unbranched channel having an opening at each end, one such opening being adjacent said entry ports and the other said opening being adjacent to said exit port.