초록 ▼

Aphthous ulcers and other lesions of the mucosal, submucosal, epidermal, dermal or subcutaneous tissue of the mouth are treated by a method comprising administering to a patient suffering from such lesion a topical preparation containing sucralfate as an essential ingredient. The invention is also d

Aphthous ulcers and other lesions of the mucosal, submucosal, epidermal, dermal or subcutaneous tissue of the mouth are treated by a method comprising administering to a patient suffering from such lesion a topical preparation containing sucralfate as an essential ingredient. The invention is also drawn to a preparation comprising sucralfate as an essential ingredient, and a method for preparing the same. The sucralfate is combined with an appropriate pharmaceutical medium to form a homogenous mixture which can then be dispersed in other media to form a preparation useful for topical application to the lesion.

대표청구항 ▼

[ We claim:] [1.] A method of treating a patient suffering from an aphthous ulcer, the method comprising administering to said patient a topical preparation containing sucralfate as an essential ingredient, wherein:(a) the sucralfate is admixed with an aqueous carboxypolymethylene medium containing

[ We claim:] [1.] A method of treating a patient suffering from an aphthous ulcer, the method comprising administering to said patient a topical preparation containing sucralfate as an essential ingredient, wherein:(a) the sucralfate is admixed with an aqueous carboxypolymethylene medium containing polysorbate 80 and simethicone, said medium being added to said sucralfate in an amount sufficient to form a paste;(b) the mixture is allowed to dry; and(c) the resulting material is dispersed in an aqueous methylcellulose medium; wherein said preparation is topically applied to said aphthous ulcer in an amount sufficient to cover said aphthous ulcer.