초록 ▼

A composite surgical material comprising a collagen matrix reinforced by a layer of a synthetic bioabsorbable material such as polylactide/polyglycolide or oxidized regenerated cellulose, and wherein oil droplets are dispersed in the collagen matrix. The oil droplets comprise 1% to 75% of the weight

A composite surgical material comprising a collagen matrix reinforced by a layer of a synthetic bioabsorbable material such as polylactide/polyglycolide or oxidized regenerated cellulose, and wherein oil droplets are dispersed in the collagen matrix. The oil droplets comprise 1% to 75% of the weight of the composite and result in improved leak-proofing of the composite. The composite, in the form of a sheet or a tube, is especially useful as a temporary, fully bioabsorbable prosthesis, for membranes or blood vessels where a highly leak-proof prosthesis is required. The invention also provides a method of making a composite surgical material comprising the steps of: providing a layer of a synthetic bioabsorbable material; providing a dispersion of collagen in an oil-in-water emulsion; coating at least one face of the layer of synthetic bioabsorbable material with the said dispersion; and drying the composite material thus obtained.

대표청구항 ▼

[ We claim:] [1.] A process to prepare a composite surgical material comprising the steps of:providing a layer of a synthetic bioabsorbable material;providing a dispersion of collagen in an oil-in-water emulsion;coating at least one face of the layer of synthetic bioabsorbable material with the said

[ We claim:] [1.] A process to prepare a composite surgical material comprising the steps of:providing a layer of a synthetic bioabsorbable material;providing a dispersion of collagen in an oil-in-water emulsion;coating at least one face of the layer of synthetic bioabsorbable material with the said dispersion; anddrying the composite material thus obtained.