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Composition and methods for transdermal delivery of acid labile drugs 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-013/02
출원번호 US-0863563 (1997-05-27)
발명자 / 주소
  • Li Chensheng
출원인 / 주소
  • Noven Pharmaceuticals, Inc.
대리인 / 주소
    Foley & Lardner
인용정보 피인용 횟수 : 60  인용 특허 : 7

초록

A transdermal composition and related method are described. Specifically, the transdermal composition is substantially free of gestodene or substantially free of isopropyl myristate and substantially free of lower alkanols and comprises: (a) a therapeutically effective amount of a pharmacologically

대표청구항

[ What is claimed is:] [1.] A transdermal composition substantially free of weak organic acids, of lower alkanols and of gestodene, the composition comprising (a) a therapeutically effective amount of a pharmacologically active drug subject to acid catalyzed degradation; (b) a pharmaceutically accep

이 특허에 인용된 특허 (7)

  1. Cooper, Eugene R., Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone.
  2. Patel Dinesh C. (Murray UT) Chang Yunik (Lakewood NJ), Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols.
  3. Rajadhyaksha Vithal J. (5724 Remington Cir. ; #1709 Fort Worth TX 76132) Graham Richard S. (5066 Balsawood Irvine CA 92715), Penetration enhancers.
  4. Chiang Chia-Ming (Foster City CA) Tenzel Renee A. (Mountain View CA), Solid matrix system for transdermal drug delivery.
  5. Heiber Sonia (Salt Lake City UT) Patel Dinesh (Murray UT) Ebert Charles D. (Salt Lake City UT), Sorbitan esters as skin permeation enhancers.
  6. Patel Dinesh C. (Murray UT) Ebert Charles D. (Salt Lake City UT), Subsaturated transdermal drug delivery device exhibiting enhanced drug flux.
  7. Sharma Kuldeepak (Mountain View CA) Dunbar Darth M. (San Mateo CA), Transdermal administration of short or intermediate half-life benzodiazepines.

이 특허를 인용한 특허 (60)

  1. Kanios, David P.; Mantelle, Juan A., Compositions and methods for delivery of amino-functional drugs.
  2. Liao, Jun; Liu, Puchun; Dinh, Steven, Compositions and methods for the transdermal delivery of methylphenidate.
  3. Kisak, Edward; Buyuktimkin, Nadir; Buyuktimkin, Servet; Newsam, John; Wen, Jianye; Shudo, Jutaro; Jain, Amit, Compositions and methods for transdermal delivery of hormones and other medicinal agents.
  4. Kisak, Edward; Buyuktimkin, Nadir; Buyuktimkin, Servet; Newsam, John; Wen, Jianye; Shudo, Jutaro; Jain, Amit, Compositions and methods for transdermal delivery of hormones and other medicinal agents.
  5. Kanios, David, Compositions and methods to effect the release profile in the transdermal administration of active agents.
  6. Breitenbach, Armin, Device for the transdermal administration of a rotigotine base.
  7. Houze, David, Enhanced drug delivery in transdermal systems.
  8. Houze, David, Enhanced drug delivery in transdermal systems.
  9. Houze, David, Enhanced drug delivery in transdermal systems.
  10. Houze, David; Nguyen, Viet, Enhanced drug delivery in transdermal systems.
  11. Houze, David; Nguyen, Viet, Enhanced drug delivery in transdermal systems.
  12. Houze,David; Nguyen,Viet, Enhanced drug delivery in transdermal systems.
  13. Breitenbach, Armin; Wolff, Hans-Michael, Hot melt TTS for administering rotigotine.
  14. Breitenbach, Armin; Wolff, Hans-Michael, Hot-melt TTS for administering rotigotine.
  15. Rimpler,Stephan; Grapatin,Sabine; Krein,Cliff; Thelen,Markus, Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients.
  16. Li, Gai Ling; Bouwstra, Johanna Aaltje; Wolff, Hans Michael; Nugroho, Akhmad Karis, Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease.
  17. Reder, Robert F.; Goldenheim, Paul D.; Kaiko, Robert F., Method of providing sustained analgesia with buprenorphine.
  18. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  19. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  20. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorpine.
  21. Robert Martin Gale, Methods for transdermal drug administration.
  22. Kulakofsky, Joshua; Liu, Puchun, Multi-polymer compositions for transdermal drug delivery.
  23. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  24. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  25. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  26. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  27. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  28. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  29. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  30. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  31. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  32. Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  33. Bernick, Brian A.; Persicaner, Peter H. R.; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
  34. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  35. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  36. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Progesterone formulations.
  37. Chien,Te Yen, Skin permeation enhancement composition for transdermal hormone delivery system.
  38. Sylvia Rossi-Montero ; Juan Mantelle ; David Kanios ; David Houze, Solubility enhancement of drugs in transdermal drug delivery systems and methods of use.
  39. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Irani, Neda; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Soluble estradiol capsule for vaginal insertion.
  40. Shadiack, Annette; Persicaner, Peter H. R.; Inskeep, Philip B.; Thorsteinsson, Thorsteinn; Sancilio, Frederick D.; Legassie, Jason D., Steroid hormone pharmaceutical composition.
  41. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  42. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  43. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  44. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  45. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  46. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  47. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  48. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  49. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system.
  50. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  51. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  52. Patel, Prashant; Nguyen, Viet; Liao, Jun, Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol.
  53. Patel, Prashant; Nguyen, Viet; Liao, Jun, Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol.
  54. Chien, Te-Yen, Transdermal hormone delivery system: compositions and methods.
  55. Chien, Te-Yen, Transdermal hormone delivery system: compositions and methods.
  56. Chien, Te-Yen, Transdermal hormone delivery system: compositions and methods.
  57. Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Irani, Neda; Sancilio, Frederick D., Transdermal hormone replacement therapies.
  58. Müller, Walter; Peck, James V., Transdermal therapeutic system and method of use thereof for treating parkinsonism.
  59. Bernick, Brian A.; Amadio, Julia M., Vaginal inserted estradiol pharmaceutical compositions and methods.
  60. Mirkin, Sebastian; Amadio, Julia M.; Bernick, Brian A., Vaginal inserted estradiol pharmaceutical compositions and methods.
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