초록 ▼

The healing of wounds is enhanced by contacting the wound surfaces with a dressing of D-glucose polysaccharide obtained by hydrolysis of starch containing ascorbic acid, collagen type I and alpha-tocopherol acetate. The collagen type I, and the ascorbic acid in the dressing are the typical chemotact

The healing of wounds is enhanced by contacting the wound surfaces with a dressing of D-glucose polysaccharide obtained by hydrolysis of starch containing ascorbic acid, collagen type I and alpha-tocopherol acetate. The collagen type I, and the ascorbic acid in the dressing are the typical chemotactic agents of neutrophils, fibroblasts and/or endothelial cells. These combinations can be present in the dressing as a gel. The composition material can be applied to the wound as a particulate material such as a powder, or as material such as a gel, paste, dispersion, solution or syrup. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, severe cuts and abrasions which are commonly resistant to the natural healing process, may be treated with this composition. The application of this combination to open wounds greatly accelerates the rate of healing and reduces scarring. The invention includes an article useful in the therapy for surface wounds comprising the suspension of particles on non-adherent gauze and a bandage tape.

대표청구항 ▼

[ What is claimed in this invention is:] [1.] A composition for use in promoting the healing of surface wound, comprising a liquid aqueous suspension of vitamins C and E and collagen type I in admixture with a starch hydrolysate with a DE of less than 35 that exhibits a chemotactic effect on fibrobl

[ What is claimed in this invention is:] [1.] A composition for use in promoting the healing of surface wound, comprising a liquid aqueous suspension of vitamins C and E and collagen type I in admixture with a starch hydrolysate with a DE of less than 35 that exhibits a chemotactic effect on fibroblasts or endothelial cells, wherein the collagen type I is purified from human placenta and the collagen is present in the suspension at a concentration of about 0.2 to 2 .mu.g/cm.sup.2.