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Oligonucleotide arrays 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C07H-021/02
출원번호 US-0870514 (1997-06-06)
발명자 / 주소
  • Heyneker Herbert L.
출원인 / 주소
  • EOS Biotechnology, Inc.
대리인 / 주소
    Flehr Hohbach Test Albritton & Herbert LLPBrezner, Esq.
인용정보 피인용 횟수 : 56  인용 특허 : 12

초록

The invention relates to novel oligonucleotide arrays.

대표청구항

[ I claim:] [1.] An oligonucleotide array comprising a solid support comprising a plurality of different oligonucleotide pools, each oligonucleotide pool arranged in a distinct linear row to form an immobilized oligonucleotide stripe, wherein the length of each stripe is greater than its width.

이 특허에 인용된 특허 (12)

  1. Southern Edwin (Oxford GB2), Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays.
  2. Guire Patrick E. (Eden Prairie MN), Biocompatible coating for solid surfaces.
  3. Guire Patrick E. (Eden Prairie MN), Biocompatible device with covalently bonded biocompatible agent.
  4. Guire Patrick (Eden Prairie MN) Dunkirk Shawn G. (Eden Prairie MN), Biomolecule attachment to hydrophobic surfaces.
  5. Nishioka Gary M. (Pataskala OH), Generation of combinatorial libraries.
  6. Guire Patrick (Eden Prarie MN) Dunkirk Shawn G. (Eden Prarie MN), Method of biomolecule attachment to hydrophobic surfaces.
  7. Guire Patrick E. (Eden Prairie MN), Method of improving the biocompatibility of solid surfaces.
  8. Rava Richard P. (San Jose CA) Fodor Stephen P. A. (Palo Alto CA) Trulson Mark (San Jose CA), Methods for making a device for concurrently processing multiple biological chip assays.
  9. Elsner Henrik (Bronshoj DKX) Mouritsen Soren (Birkerod DKX), Modification of polymer surfaces and molecular immobilization by photoreaction.
  10. Guire Patrick E. (Eden Prairie MN) Dunkirk Shawn G. (Eden Prairie MN) Josephson Mark W. (Richfield MN) Swanson Melvin J. (Carver MN), Preparation of polymeric surfaces via covalently attaching polymers.
  11. Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Synthesis and screening of immobilized oligonucleotide arrays.
  12. Nishioka Gary M. (Pataskala OH), Synthesis of chain chemical compounds.

이 특허를 인용한 특허 (56)

  1. Gotoda, Masaharu; Yoshida, Kenshi; Shibuguchi, Nao, Amorphous form of quinoline derivative, and method for producing same.
  2. Matsui, Junji, Antitumor agent for thyroid cancer.
  3. Yamamoto, Yuji; Matsushima, Tomohiro; Tsuruoka, Akihiko; Obaishi, Hiroshi; Nakagawa, Takayuki, Antitumor agent for undifferentiated gastric cancer.
  4. Nakagawa, Takayuki; Matsushima, Tomohiro; Funahashi, Yasuhiro, Antitumor agent using compounds having kinase inhibitory effect in combination.
  5. Webb, Peter G., Array fabrication.
  6. Ellson, Richard N., Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy.
  7. Ofstead, Ronald F.; Swanson, Melvin J.; Swan, Dale G., Attachment of molecules to surfaces.
  8. Ofstead, Ronald F.; Swanson, Melvin J.; Swan, Dale G., Attachment of molecules to surfaces.
  9. Ofstead,Ronald F.; Swanson,Melvin J.; Swan,Dale G., Attachment of molecules to surfaces.
  10. Funahashi, Yasuhiro; Kadowaki, Tadashi; Matsui, Junji; Simon, Jason S.; Xu, Lucy, Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds.
  11. Lee,Kan Hung; Shih,Yu Hau; Tsai,Chuan Mei; Wang,Yih Weng; Hsiao,Hsiung; Bair,Chi Horng; Wang,Shin Hwan, Biomolecule-bound substrates.
  12. Corson, John F., Biopolymeric arrays having replicate elements.
  13. Corson, John F., Biopolymeric arrays having replicate elements.
  14. Yamamoto, Yuji, Combination of anti-angiogenic substance and anti-tumor platinum complex.
  15. Bruhn, Laurakay; Scheffer, Alicia F.; Barrett, Michael T.; Amorese, Douglas A.; Laderman, Stephen S., Comparative genomic hybridization assays using immobilized oligonucleotide features and compositions for practicing the same.
  16. Yamamoto, Yuji, Composition for treatment of undifferentiated gastric cancer.
  17. Wiyatno, Willy; Lee, Linda; Cox, David; Reel, Richard; Oldham, Mark; Nurse, Jim; Greiner, Douglas; Lehto, Dennis; Wojtowicz, Janusz; Woo, Sam, Device and method for making discrete volumes of a first fluid in contact with a second fluid, which are immiscible with each other.
  18. Tajima,Hideji, Device for containing, reacting and measuring, and method of containing, reacting and measuring.
  19. Schroeder, Benjamin G.; Cox, David M.; Oldham, Mark F.; Reel, Richard T.; Wiyatno, Willy, Device, system, and method for depositing processed immiscible-fluid-discrete-volumes.
  20. Swan, Dale G.; Swanson, Melvin J., Epoxide polymer surfaces.
  21. Swan,Dale G.; Swanson,Melvin J., Epoxide polymer surfaces.
  22. Nakamura, Taiju; Abe, Taichi; Miyashita, Yusuke; Kuroda, Hirofumi; Ayata, Yusuke; Akao, Atsushi, High-purity quinoline derivative and method for manufacturing same.
  23. Tadashi Okamoto JP; Nobuko Yamamoto JP; Tomohiro Suzuki JP, Ink jet method of spotting a probe and manufacturing a probe array.
  24. Adey,Nils B., Laminated microarray interface device.
  25. McNeely,Michael; Adey,Nils; Spute,Mark; Ayliffe,Edward; Howard,Michael; Beutel,Darin; Jensen,John; Coffin,Stephen; Moyer,Thomas, Method and system for microfluidic interfacing to arrays.
  26. Matsui, Junji; Yamamoto, Yuji; Uenaka, Toshimitsu, Method for assay on the effect of vascularization inhibitor.
  27. Uenaka, Toshimitsu; Yamamoto, Yuji; Matsui, Junji, Method for assay on the effect of vascularization inhibitor.
  28. Bentley, William E.; Gill, Ryan, Method of differential display of prokaryotic messenger RNA by RTPCR.
  29. Okamoto, Tadashi; Yamamoto, Nobuko; Suzuki, Tomohiro, Method of spotting probes on a solid support.
  30. Bass, Jay K.; McEntee, John F.; Lazaruk, Tim J.; Mobed-Miremadi, Maryam, Methods for manufacturing arrays.
  31. Eggers, Mitchell D., Methods for multiplexed biochemical analysis.
  32. Goldberg, Martin J.; Diggelman, Martin; Hubbell, Earl A.; McGall, Glenn H.; Ngo, Nam Quoc; Morris, MacDonald; Yamamoto, Melvin; Tan, Jennifer; Rava, Richard P., Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings.
  33. Schena, Mark A., Microarray method of genotyping multiple samples at multiple LOCI.
  34. Benson, Andrew K., Multispecies food testing and characterization organoleptic properties.
  35. Furitsu, Hisao; Suzuki, Yasuyuki, Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide.
  36. Furitsu, Hisao; Suzuki, Yasuyuki, Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7=methoxy-6-quinolinecarboxide.
  37. Guire, Patrick E.; Swanson, Melvin J.; Opperman, Gary W., Photoactivatable nucleic acids.
  38. Klaerner, Gerrit; Nielsen, Ralph B.; Mansky, Paul; Benoit, Didier; Charmot, Dominique; Jandeleit, Bernd; Mazzola, Laura T., Polymer brushes for immobilizing molecules to a surface and having water-soluble or water-dispersible segments therein and probes bonded thereto.
  39. Klaerner,Gerrit; Benoit,Didier; Charmot,Dominique; Nomula,Srinivas; Piotti,Marcelo Eduardo; Mazzola,Laura T., Polymer brushes for immobilizing molecules to a surface or substrate having improved stability.
  40. Klaerner, Gerrit; Nielsen, Ralph B.; Mansky, Paul; Benoit, Didier; Charmot, Dominique; Jandeleit, Bernd; Mazzola, Laura T., Polymer brushes for immobilizing molecules to a surface or substrate, where the polymers have water-soluble or water-dispersible segments and probes bonded thereto.
  41. Kaufman, Joseph C., Producing, cataloging and classifying sequence tags.
  42. Kaufman, Joseph C., Producing, cataloging and classifying sequence tags.
  43. Anderson, Norman G.; Anderson, N. Leigh, Reference database.
  44. Anderson, Norman G.; Anderson, N. Leigh, Reference database.
  45. Anderson,Norman G.; Anderson,N. Leigh, Reference database.
  46. Anderson,Norman G.; Anderson,N. Leigh, Reference database.
  47. Guire, Patrick E.; Swanson, Melvin J., Replicable probe array.
  48. Melvin J. Swanson, Solid phase synthesis method and reagent.
  49. Goldberg, Martin J; Diggelman, Martin; Hubbell, Earl A.; McGall, Glenn H.; Ngo, Nam Quoc; Morris, MacDonald; Yamamoto, Melvin; Tan, Jennifer; Rava, Richard P., Substrate preparation process.
  50. Tajima,Hideji, Support for substances for detection, apparatus for processing same, method of processing same, apparatus for making same, and method of making same.
  51. Goldberg, Martin J.; Diggelman, Martin; Hubbell, Earl A.; McGall, Glenn H.; Nam, Ngo; Morris, MacDonald S.; Yamamoto, Melvin; Tan, Jennifer; Rava, Richard, System for photolithographic synthesis of polymer arrays.
  52. Chappa, Ralph A.; Hu, Sheau-Ping; Swan, Dale G.; Swanson, Melvin J.; Guire, Patrick E., Target molecule attachment to surfaces.
  53. Ralph A. Chappa ; Sheau-Ping Hu ; Dale G. Swan ; Melvin J. Swanson ; Patrick E. Guire, Target molecule attachment to surfaces.
  54. Ogura,Nobuhiko, Test piece, method of and apparatus for manufacturing the test piece and method of and system for reading the same.
  55. Narita, Yusuke; Matsui, Junji; Funahashi, Yasuhiro, Therapeutic agent for tumor.
  56. Yamamoto, Yuji, Use of combination of anti-angiogenic substance and c-kit kinase inhibitor.
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