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Methods of forming outserts used to provide printed information to the users and purchasers of pharmaceutical products in which a sheet of paper is folded a number of times in a direction parallel to a first direction and then folded a number of times in a second direction perpendicular to the first

Methods of forming outserts used to provide printed information to the users and purchasers of pharmaceutical products in which a sheet of paper is folded a number of times in a direction parallel to a first direction and then folded a number of times in a second direction perpendicular to the first direction. The folds in the second direction are made to produce an outsert having no unfolded exterior sheet edges which lie in a direction parallel to the second direction.

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[ What is claimed is:] [1.] A method of producing a folded item having printed information thereon to provide information to the user of a product, said folded item having a plurality of sheet portions, said method comprising the steps of:(a) forming a first folded article having a first end, a seco

[ What is claimed is:] [1.] A method of producing a folded item having printed information thereon to provide information to the user of a product, said folded item having a plurality of sheet portions, said method comprising the steps of:(a) forming a first folded article having a first end, a second end, a length along a first direction, and a width along a second direction perpendicular to said first direction, said first folded article having a plurality of first elongate sheet portions and a plurality of second elongate sheet portions, each of said first elongate sheet portions having a first end and a second end, and each of said second elongate sheet portions having a first end and a second end, each of said first ends of said first elongate sheet portions being joined to a respective one of said first ends of said second elongate sheet portions at a respective fold coinciding with said first end of said first folded article so that said first end of said first folded article has no exterior unfolded sheet edges, each of said respective folds being parallel to said second direction;(b) folding said first folded article by making a transverse fold in said first folded article to form a second folded article, said second folded article having a first end and a second end, said transverse fold in said first folded article being parallel to said second direction and being made so that said second end of said first folded article is disposed between said first end of said second folded article and said second end of said second folded article;(c) depositing an adhesive on a portion of said second folded article; and(d) making at least one additional transverse fold in said second folded article in a direction parallel to said second direction to form said folded item, said at least one additional transverse fold being made so that said second end of said first folded article is covered by one of said sheet portions of said folded item and so that said folded item has no exterior unfolded sheet edges that lie in a direction parallel to said second direction.