[특허]Method of forming adhesive patch for applying medication to the skin

[미국특허] Method of forming adhesive patch for applying medication to the skin 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-013/00 A61L-015/16
출원번호	US-0947089 (1997-10-08)
발명자 / 주소	Rolf David Sjoblom Urmann Elisabeth K.
출원인 / 주소	LecTec Corporation
대리인 / 주소	Viharmon
인용정보	피인용 횟수 : 17 인용 특허 : 30

초록 ▼

A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir. The medication within the reservoir migrates over time from within the backing through the lower coating layer and passes through the skin to provide sustained release of the medication into the body of a patient.

대표청구항 ▼

[ What is claimed is:] [1.] A method of forming a medication-containing adhesive patch to be applied to the skin for releasing a medication into the body of a patient comprising,(a) providing a flexible porous backing layer in sheet form to serve as a support for the patch, said layer having a lower portion and an upper portion with an upper surface,(b) applying an adhesive mass containing a medication to the flexible porous backing layer such that the adhesive mass penetrates into the backing layer to act as a gel matrix for the medication,(c) providing the adhesive mass with an external exposed first portion for bonding to the skin of the patient,(d) controlling the forming of said adhesive patch to keep the adhesive mass(1) sufficiently fluid to penetrate the backing layer while(2) limiting the penetration of the adhesive mass within the backing layer to said lower portion thereof such that the adhesive mass has a second portion infiltrated within only the lower portion of the porous backing layer, and(3) maintaining said upper portion of the backing layer free of the adhesive mass,(e) the backing layer acts as a storage location for the medication-containing adhesive such that the adhesive releases the medication into the body of the patient through an exposed surface thereof that is bonded to the patient's skin, and(f) solidifying the adhesive mass within said lower portion of said backing layer to cause the upper surface of said porous backing layer to remain spaced apart from the gel matrix.

이 특허에 인용된 특허 (30) 인용/피인용 타임라인 분석

Ethier Dolores O. (White Bear Lake MN), Bilayer substrate.
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Anderson Clifford J. (St. Paul MN) Gumbusky James T. (South St. Paul MN), Bio-medical electrode conductive gel pads.
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Strand Jerome E. (Hudson WI), Biomedical electrode.
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Reever Richard (Plato MN) Lundmark Larry (Brooklyn Park MN) Kapsner Timothy (Minneapolis MN), Composition for transdermal drug delivery.
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Scharnberg Lorne C. (West Des Moines IA), Defibrillator pad assembly and method for using same.
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Tsuk Andrew G. (Plattsburgh NY) Martin Frederick H. (West Chazy NY), Dosage form.
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Hymes Alan C. (Minnetonka MN) Ong Lincoln T. (Minnetonka MN) Persons Garry R. (Edina MN), Drug dispensing device for transdermal delivery of medicaments.
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Szycher Michael (Lynnfield MA) Dempsey Donald J. (Newbury MA) Rolfe Jonathan L. (North Easton MA), Drug release system.
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Karmann Werner (Hamburg DEX) Weidehaas Gerd (Hamburg DEX) Hwe Bernd (Hamburg DEX) Piel Frank (Hamburg DEX), Electrically conductive, visco-elastic gel and its use in electrode.
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Miller Larry L. (Minneapolis MN) Blankespoor Ronald L. (Grand Rapids MI) Zinger Baruch (Rehovot ILX), Electrochemical controlled release drug delivery system.
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Yamamoto Katsuhiro (Osaka JPX) Matsumoto Katsuo (Osaka JPX) Okada Yoshiyuki (Osaka JPX), Electrode pad.
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Powers Whitney R. (Topsfield MA) Sisun Henry (Pawtucket RI), Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologica.
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Keusch Preston (220 E. 84th St. ; Apt. 3-D New York NY 10028) Czap Christine A. (197 Oriol Dr. Montgomery NY 12549) Murdock Keith A. (288 Haverstraw Rd. Suffern NY 10901) Lennon Linda (R.D. 1 ; Box 8, Highly conductive non-stringy adhesive hydrophilic gels and medical electrode assemblies manufactured therefrom.
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Jevne Allan H. (Anoka MN) Vegoe Brett R. (Brooklyn Park MN) Holmblad Carolann M. (Cambridge MN) Cahalan Patrick T. (Champlin MN), Hydrophilic pressure sensitive biomedical adhesive composition.
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Ariura Shunsuke (Matsudo JPX) Ogata Tadashi (Fuchu JPX) Kashima Norie (Tokyo JPX) Morihata Michiyo (Fuchu JPX), Iontophoresis device.
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Buchalter Gilbert (555 Mount Prospect Ave. Newark NJ 07104), Method of transmitting ultrasonic impulses to surface using transducer coupling agent.
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Perrault James J. (Brooklyn Center MN) Jordan George (Fairfield CT), Methods for detecting dehydration of a biomedical hydrogel.
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Hymes ; Alan C., Monitoring and stimulation electrode.
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Hymes Alan C. (Hopkins MN), Monitoring and stimulation electrode.
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Montecalvo David A. (Eden Prairie MN) Rolf David (Minneapolis MN), Multipurpose medical stimulation electrode.
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Lattin Gary A. (Forest Lake MN) Spevak Richard P. (Moundsview MN), Non-invasive diagnosis method.
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Couvillon ; Jr. ; Lucien Alfred ; Grover ; Thomas Reaks ; Baker ; Charl es Dewitt ; Topham ; William Sanford, Noninvasive, continuous intraocular pressure monitor.
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Lawrence Katherine (Trabuico Canyon CA), Novel gel compositions, processes for making same and uses in transmitting and measuring electrical impulses.
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Chen James L. (East Brunswick NJ) Cilento Rudolfo D. (North Brunswick NJ) Hill John A. (New Brunswick NJ) La Via Anthony L. (East Brunswick NJ), Ostomy adhesive.
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Vegoe Brett R. (Mound MN), Process for making biomedical devices utilizing thermoplastic hydrophilic gels.
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Rolf David (Minneapolis MN) Shelton Michael F. (Edina MN), Protective wrap for preventing damage to girdled trees and other plants and method.
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Rolf David (Minneapolis MN), Protective wrap for trees and other plants.
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Hymes Alan C. (Hopkins MN) Ong Lincoln T. (Minnetonka MN) Persons Garry R. (Edina MN), Sterile improved bandage and sealant.
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Hymes Alan C. (Hopkins MN) Ong Lincoln T. (Minnetonka MN) Persons Garry R. (Edina MN), Sterile improved bandage containing a medicament.
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Campbell Patricia S. (Palo Alto CA) Eckenhoff James B. (Los Altos CA), Transdermal therapeutic system having improved delivery characteristics.
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이 특허를 인용한 특허 (17) 인용/피인용 타임라인 분석

Teri Buseman ; David Rolf ; Daniel M. McWhorter, Acne patch.
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Park, Han-Wook, Apparatus and method for manufacturing dried gel sheet and gel sheet or beauty pack manufactured by the same.
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Gueret, Jean-Louis H., Device for applying a product and method for manufacturing device.
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Gueret, Jean-Louis, Device having a magnetic applicator and/or wiper member.
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Cassel, R. Douglas, Local prevention or amelioration of pain from surgically closed wounds.
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Henry,Steven D.; Graham,Bryan, Medicine dispensing patch.
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Miller, II, Kenneth J., Method for making a multilayer adhesive laminate.
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Miller, Kenneth J., Method for making a multilayer adhesive laminate.
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Mori, Tatsuya; Saida, Naoyuki, Non-aqueous patch.
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Mori, Tatsuya; Saida, Naoyuki, Non-aqueous patch.
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Mori, Tatsuya; Saida, Naoyuki, Non-aqueous patch.
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Joulia, Gerard, Process for molding a make-up composition.
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Alan C. Hymes, Therapeutic method for treating acne or isolated pimples and adhesive patch therefor.
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Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
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Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
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Miller, II, Kenneth J., Transdermal patch incorporating active agent migration barrier layer.
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Gueret,Jean Louis H., Treatment device and method of using the same.
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IPC	Description
A	생활필수품
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A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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[미국특허] Method of forming adhesive patch for applying medication to the skin 원문보기