초록 ▼

The present invention is an apparatus and method that maintains a constant drug delivery rate for an electrotransport delivery system, while the apparent transport efficiency of the system varies, by making adjustments to the output current of the system. More specifically, the constant drug deliver

The present invention is an apparatus and method that maintains a constant drug delivery rate for an electrotransport delivery system, while the apparent transport efficiency of the system varies, by making adjustments to the output current of the system. More specifically, the constant drug delivery rate is maintained by the regulator of the electrotransport delivery system automatically adjusting the output current to compensate for the varying apparent transport efficiency.

대표청구항 ▼

[ We claim:] [1.]1. A method of regulating an electrotransport system delivering a beneficial agent by supplying a load current across a first electrode and a second electrode, the method comprising the steps of:(a) generating a load current in accordance with a load current pattern; and(b) supplyin

[ We claim:] [1.]1. A method of regulating an electrotransport system delivering a beneficial agent by supplying a load current across a first electrode and a second electrode, the method comprising the steps of:(a) generating a load current in accordance with a load current pattern; and(b) supplying the generated load current to the electrodes, wherein the supplied load current achieves a sought load current which is inversely proportional to an apparent transport efficiency of the beneficial agent when a constant beneficial agent delivery rate is maintained,(c) wherein the apparent transport efficiency of the beneficial agent is the desired average current is re ATE.sub.o and i.sub.o are an initial apparent transport efficiency and an initial sought load current, respectively, K.sub.ATE is a rate constant, and t is time,(d) wherein the load current is a pulsed current and the load current is adjusted by adjusting one of the magnitude, time, and the duty cycle of the pulse, and(e) wherein the method is implemented in an interchangeable circuit board or component.