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Functionalized nanocrystals and their use in labeling for strand synthesis or sequence determination 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12P-019/34
  • C12Q-001/68
  • G01N-033/533
  • G01N-021/64
  • G01N-003/30
출원번호 US-0436159 (1999-11-09)
발명자 / 주소
  • Barbera-Guillem Emilio
  • Nelson M. Bud
  • Castro Stephanie L.
출원인 / 주소
  • Bio-Pixels Ltd.
대리인 / 주소
    Nelson
인용정보 피인용 횟수 : 55  인용 특허 : 4

초록

Provided are compositions comprising functionalized nanocrystal-labeled nucleobases that are produced by operably linking a nucleobase to a functionalized nanocrystal via reactive functionalities. Also provided are kits comprising a plurality of species of functionalized nanocrystal-labeled nucleoba

대표청구항

[ What is claimed is:] [1.]1. A functionalized nanocrystal-labeled nucleobase comprising a functionalized nanocrystal operably linked to a nucleobase; wherein the functionalized nanocrystal comprises a core and a shell, a capping compound comprising a compound having the formula HS(CH.sub.2).sub.n X

이 특허에 인용된 특허 (4)

  1. Hille Hans-Dieter (Bergisch Gladbach DEX) Harten Rolf (Mnster DEX), Aqueous dispersions based on a polyurethane synthetic resin.
  2. Favi Claude (Pau FRX) Mercadier Michel (Pau FRX), Cosmetological polymers.
  3. Amagi Akikazu,JPX ; Uemura Nobuyuki,JPX ; Takeuchi Motoharu,JPX ; Takahashi Kenichi,JPX ; Ohashi Minoru,JPX ; Horikoshi Hiroshi,JPX ; Shimuta Masanori,JPX, Episulfide compound.
  4. Weiss Shimon ; Bruchez ; Jr. Marcel ; Alivisatos Paul, Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such p.

이 특허를 인용한 특허 (55)

  1. Ignatius, Michael J.; Molokanova, Elena; Savtchenko, Alexei; Bartel, Joseph A.; Zhao, Weiwen; Treadway, Joseph A., Activation and monitoring of cellular transmembrane potentials.
  2. Archer, Robert A.; Beechem, Joseph M.; Hagen, David C.; Haugland, Richard P.; Haugland, Rosaria P., Antibody complexes and methods for immunolabeling.
  3. Archer, Robert; Haugland, Richard; Haugland, Rosaria; Beechem, Joseph; Hagen, David, Antibody complexes and methods for immunolabeling.
  4. Burba, III, John L.; Hassler, Carl R.; O'Kelley, C. Brock; Lupo, Joseph A.; Pascoe, Joseph R., Apparatus for treating a flow of an aqueous solution containing arsenic.
  5. Pinaud, Fabien; King, David; Weiss, Shimon, Bioactivation of particles.
  6. Ying, Jackie Y.; Selvan, Subramanian T.; Yi, Dong Kee; Lee, Su Seong, Coated composites of magnetic material and quantum dots.
  7. Ying,Jackie Y.; Selvan,Subramanian T.; Tan,Timothy T., Coated water-soluble nanoparticles comprising semiconductor core and silica coating.
  8. Burba, John, Composition and process for making the composition.
  9. Witham, Richard Donald; McNew, Edward Bayer; Burba, III, John Leslie, Composition for removing arsenic from aqueous streams.
  10. Burba, III, John L., Composition for treating a fluid.
  11. Pickett, Nigel, Controlled preparation of nanoparticle materials.
  12. Naasani, Imad; Gillies, James; Fitzgerald, Emma; Wang, Xiaojuan; Masala, Ombretta, Encapsulated nanoparticles.
  13. Naasani, Imad; Gillies, James; Hogarth, Emma; Wang, Xiaojuan; Masala, Ombretta, Encapsulated nanoparticles.
  14. Harris, James; Pickett, Nigel, Fabrication of electrically active films based on multiple layers.
  15. Zehnder, Donald A.; Bruchez, Marcel P.; Treadway, Joseph A.; Earhart, Jonathan P., Flow synthesis of quantum dot nanocrystals.
  16. Zehnder,Donald A.; Bruchez,Marcel P.; Treadway,Joseph A.; Earhart,Jonathan P., Flow synthesis of quantum dot nanocrystals.
  17. Barbera Guillem,Emilio, Functionalized encapsulated fluorescent nanocrystals.
  18. Barbera Guillem,Emilio, Functionalized encapsulated fluorescent nanocrystals.
  19. Naasani, Imad, Functionalized fluorescent nanocrystal compositions and methods for their preparation.
  20. Naasani, Imad, Functionalized fluorescent nanocrystal compositions and methods for their preparation.
  21. Naasani,Imad, Functionalized fluorescent nanocrystals, and methods for their preparation and use.
  22. Naasani,Imad, Highly luminescent functionalized semiconductor nanocrystals for biological and physical applications.
  23. Harris, James; Pickett, Nigel, Hybrid photovoltaic cells and related methods.
  24. Lin, Shu-Yi; Lo, Leu-Wei; Yang, Chung-Shi, Method for making a ligand-quantum dot conjugate.
  25. Koenig, Karsten; Halbhuber, Karl-Juergen; Fischer, Peter; Riemann, Iris, Method for optical excitation of fluorophore marked DNA and RNA.
  26. Pickett, Nigel; McCairn, Mark C., Method for producing aqueous compatible nanoparticles.
  27. Ying, Jackie Y.; Selvan, Subramanian T.; Tan, Timothy T., Method of forming coated water-soluble nanoparticles by inverse emulsion.
  28. Lagwinski, Willy; Harrington, Charles; Phelps, Bruce, Methods for verifying fluid movement.
  29. Lagwinski,Willy; Harrington,Charles A.; Phelps,Bruce H., Methods for verifying fluid movement.
  30. Naasani, Imad, Nanocrystals.
  31. Naasani,Imad, Nanocrystals.
  32. Pickett, Nigel; Daniels, Steven; O'Brien, Paul, Nanoparticles.
  33. Weiss, Shimon; Tsay, James M.; Pinaud, Fabien; Doose, Soren, Peptide-coated nanoparticles with graded shell compositions.
  34. Barbera-Guillem, Emillo; Nelson, M. Bud; Castro, Stephanie L., Polynucleotide strands operably linked to nanocrystals functionalized to be water soluble.
  35. Pickett, Nigel; Harris, James, Preparation of nanoparticle material.
  36. Pickett, Nigel; Harris, James, Preparation of nanoparticle material.
  37. O'Brien, Paul; Pickett, Nigel, Preparation of nanoparticle materials.
  38. O'Brien, Paul; Pickett, Nigel, Preparation of nanoparticle materials.
  39. O'Brien, Paul; Pickett, Nigel, Preparation of nanoparticle materials.
  40. O'Brien, Paul; Pickett, Nigel, Preparation of nanoparticle materials.
  41. Burba, III, John L.; Oriard, Tim L., Process and apparatus for treating a gas containing a contaminant.
  42. Bawendi, Moungi E.; Heine, Jason; Jensen, Klavs F.; Miller, Jeffrey N.; Moon, Ronald L., Quantum dot white and colored light-emitting devices.
  43. Bawendi, Moungi G.; Heine, Jason; Jensen, Klavs F.; Miller, Jeffrey N.; Moon, Ronald L., Quantum dot white and colored light-emitting devices.
  44. Bawendi, Moungi G.; Heine, Jason; Jensen, Klavs F.; Miller, Jeffrey N.; Moon, Ronald L., Quantum dot white and colored light-emitting devices.
  45. Cable, Robert; Hassler, Carl; Burba, John, Rare earth removal of hydrated and hydroxyl species.
  46. Psaras, Dimitrios; Gao, Yuan; Haneline, Mason; Lupo, Joseph; Landi, Carol, Removal of arsenic from aqueous streams with cerium (IV) oxide compositions.
  47. McCairn, Mark C.; Daniels, Steven M.; Cummins, Siobhan; Pickett, Nigel, Semiconductor nanoparticle capping agents.
  48. Pickett, Nigel; Harris, James, Semiconductor nanoparticle-based light-emitting devices and associated materials and methods.
  49. Pickett, Nigel; Naasani, Imad; Harris, James, Semiconductor nanoparticle-based materials.
  50. Pickett, Nigel; Naasani, Imad; Harris, James, Semiconductor nanoparticle-based materials.
  51. Pickett, Nigel; Naasani, Imad; Harris, James, Semiconductor nanoparticle-based materials.
  52. Pickett, Nigel; McCairn, Mark C.; Daniels, Steven M.; Mushtaq, Imrana; Glarvey, Paul, Surface functionalised nanoparticles.
  53. Pickett, Nigel; McCairn, Mark C.; Daniels, Steven M.; Mushtaq, Imrana; Glarvey, Paul, Surface functionalised nanoparticles.
  54. Naasani, Imad, Synthesis of highly luminescent colloidal particles.
  55. Witham, Richard Donald; McNew, Edward Bayer; Burba, III, John Leslie, Water purification device for arsenic removal.
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