초록 ▼

As a result ofstudies conducted with polymer-cell suspensions forming interpenetrating polymer networks, it has been determined that polymer solutions can be formulated wherein the active species is provided by exposure of the polymer solution to an exogenous souce of active species, typically elect

As a result ofstudies conducted with polymer-cell suspensions forming interpenetrating polymer networks, it has been determined that polymer solutions can be formulated wherein the active species is provided by exposure of the polymer solution to an exogenous souce of active species, typically electromagnetic radiation, preferably light. Studies demonstrate that light will penetrate through skin, body fluids (such as synovial fluid) and membranes and polymerize the polymer solutions. The polymer solutions can be crosslinked ionically or covalently, to form a hydrogel, semi-interpenetrating polymer network or an interpenetrating polymer network.

대표청구항 ▼

[ We claim:] [1.]1. A method for forming a tissue equivalent in a patient, comprising:providing a suspension of dissociated cells in a solution of a biocompatible polymer, wherein the polymer crosslinks upon exposure to free radicals to form a hydrogel,injecting said suspension into a patient, andex

[ We claim:] [1.]1. A method for forming a tissue equivalent in a patient, comprising:providing a suspension of dissociated cells in a solution of a biocompatible polymer, wherein the polymer crosslinks upon exposure to free radicals to form a hydrogel,injecting said suspension into a patient, andexposing the suspension in situ to free radicals generated by electromagnetic radiation from an electromagnetic source external to the injected suspension, the electromagnetic radiation penetrates through tissue to generate the free radicals which cause polymer crosslinking and whereby the tissue equivalent forms.