초록 ▼

The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow elect

The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.

대표청구항 ▼

[ We claim:] [1.]1. A method of detecting a target analyte in a sample comprising:a) concentrating said target analyte in a detection chamber comprising a detection electrode comprising a self-assembled monolayer and a covalently attached capture ligand;b) binding said target analyte to said capture

[ We claim:] [1.]1. A method of detecting a target analyte in a sample comprising:a) concentrating said target analyte in a detection chamber comprising a detection electrode comprising a self-assembled monolayer and a covalently attached capture ligand;b) binding said target analyte to said capture ligand to form an assay complex, wherein said assay complex further comprises at least one electron transfer moiety (ETM); andc) detecting the presence of said ETM using said detection electrode.