초록 ▼

A method and device are provided for measuring the concentration of target chemical analytes present in a biological system, and then predicting a future or past concentration of an analyte using a series of such measurements. One important application of the invention involves predicting future or

A method and device are provided for measuring the concentration of target chemical analytes present in a biological system, and then predicting a future or past concentration of an analyte using a series of such measurements. One important application of the invention involves predicting future or past blood glucose concentrations using a series of measured blood glucose values.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method for measuring an analyte present in a biological system, said method comprising:(a) transdermally extracting the analyte from the biological system using a sampling system that is in operative contact with a skin or mucosal surface of said biological system;(b)

[ What is claimed is:] [1.]1. A method for measuring an analyte present in a biological system, said method comprising:(a) transdermally extracting the analyte from the biological system using a sampling system that is in operative contact with a skin or mucosal surface of said biological system;(b) obtaining a raw signal from the extracted analyte, wherein said raw signal is specifically related to the analyte;(c) performing a calibration step which correlates the raw signal obtained in step (b) with a measurement value indicative of the concentration of analyte present in the biological system at the time of extraction;(d) repeating steps (a)-(b) to obtain a series of measurement values at selected time intervals, wherein the sampling system is maintained in operative contact with the skin or mucosal surface of said biological system to provide for analyte measurement; and(e) predicting a measurement value at a further time interval which occurs either one time interval before or one time interval after the series of measurement values is obtained in step (d).