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Bioadhesive polymer compositions 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08F-020/02
  • C08F-020/10
출원번호 US-0314842 (1999-05-19)
발명자 / 주소
  • Marchant Nancy S.
  • Yu Simon Hsaio-Pao
  • Amjad Zahid
출원인 / 주소
  • PMD Holdings Corp.
대리인 / 주소
    Dunlap
인용정보 피인용 횟수 : 33  인용 특허 : 49

초록

Improved crosslinked ionic polymers or salts thereof having a soluble polymer fraction of less than about 15 wt %, and methods for making the same. The polymers are useful as bioadhesives, thickeners, emulsifiers, suspending aids, and pharmaceutical controlled release excipients.

대표청구항 ▼

[ What is claimed is:] [1.]1. A crosslinked ionic polymer or salt thereof substantially free of soluble polymer and having at least one of the following features when in deionized water at a concentration of 0.5 wt %: (i) a yield stress of between about 10 and about 200 Pa, (ii) a Brookfield viscosi

이 특허에 인용된 특허 (49)

  1. Tsubakimoto Tsuneo (Toyonaka JPX) Shimomura Tadao (Toyonaka JPX) Irie Yoshio (Ashiya JPX) Masuda Yoshihiko (Suita JPX), Absorbent resin composition and process for producing same.
    상세보기
  2. Akemi Hitoshi (Osaka JPX) Kinoshita Takashi (Osaka JPX) Otsuka Saburo (Osaka JPX) Hosaka Yoshifumi (Osaka JPX) Nakano Yoshihisa (Osaka JPX), Acrylic oily gel bioadhesive material and acrylic oily gel preparation.
    상세보기
  3. Scholz Matthew T. ; Scherrer Robert A. ; Marecki Nelda M. ; Chen Yen-Lane ; Barkhaus Joan K., Bioadhesive composition and patch.
    상세보기
  4. Rault Isabelle (Saint Lye la Foret FRX) Pichon Gerald (Orleans FRX) Cuine Alain (Saint Jean de Braye FRX), Bioadhesive pharmaceutical composition for the controlled release of active principles.
    상세보기
  5. Tapolsky Gilles H. ; Osborne David W., Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces.
    상세보기
  6. Reever Richard (Plato MN) Lundmark Larry (Brooklyn Park MN) Kapsner Timothy (Minneapolis MN), Composition for transdermal drug delivery.
    상세보기
  7. Bottenberg Peter (Eupen BEX) Remon Jean Paul Louis August (Gent BEX) De Muynck Christian Dominique Erwin (Evergem BEX) Slop Dick (Brussels BEX), Composition of a bioadhesive sustained delivery carrier for drug administration.
    상세보기
  8. Beckett Raymond Paul,GBX ; Miller Andrew,GBX ; Spavold Zoe Marie,GBX ; Whittaker Mark,GBX, Derivatives of succinamide and their use as metalloproteinase inhibitors.
    상세보기
  9. Long ; II Carl J. (Elyria OH) Amjad Zahid (Brecksville OH) Masler ; III William F. (Hinckley OH) Wingo William H. (North Royalton OH), Easy to disperse polycarboxylic acid thickeners.
    상세보기
  10. Spaulding ; David Chantrill, Flexible water absorbent polymer compositions comprising (A) unsaturated carboxylic acid, acrylic ester containing alky.
    상세보기
  11. Miyajima Tooru (Ebina JPX), High water-absorptive resin emulsion.
    상세보기
  12. Brandt Kerryn A. (Cincinnati OH) Goldman Stephen A. (Cincinnati OH) Inglin Thomas A. (Cincinnati OH), Hydrogel-forming polymer compositions for use in absorbent structures.
    상세보기
  13. Brandt Kerryn A. (Cincinnati OH) Goldman Stephen A. (Wyoming OH) Inglin Thomas A. (West Chester OH), Hydrogel-forming polymer compositions for use in absorbent structures.
    상세보기
  14. Crimmin Michael John (Cowley GBX) Beckett Raymond Paul (Cowley GBX) Davis Mark Hampton (Cowley GBX), Hydroxamic acid derivatives as metalloproteinase inhibitors.
    상세보기
  15. Dickens Jonathan Philip (Cambridge GBX) Crimmin Michael John (Cowley GBX) Beckett Raymond Paul (Cowley GBX), Hydroxamic acid derivatives as metalloproteinase inhibitors.
    상세보기
  16. Crimmin Michael John (Cowley GB3) Galloway William Alan (Cowley GB3) Gearing Andrew John Hubert (Cowley GB3), Inhibition of TNF production with matrix metaloproteinase inhibitors.
    상세보기
  17. Castelhano Arlindo Lucas ; Liak Teng Jiam,CAX ; Horne Stephen,CAX ; Krantz Alexander ; Yuan Zhengyu ; Chen Jian Jeffrey ; Cannon Paul David ; Wart Hal Van, Matrix metalloprotease inhibitors.
    상세보기
  18. Imamura Kengo,JPX ; Sonoda Hirofumi,JPX ; Takamatsu Yorinobu,JPX ; Nanakubo Hiroyasu,JPX, Medical pressure-sensitive adhesive and medical dressing material provided with the same.
    상세보기
  19. Beckett Raymond Paul,GBX ; Miller Andrew,GBX ; Whittaker Mark,GBX, Metalloproteinase inhibitors.
    상세보기
  20. Beckett Raymond Paul,GBX ; Whittaker Mark,GBX ; Miller Andrew,GBX ; Martin Fionna Mitchell,GBX, Metalloproteinase inhibitors.
    상세보기
  21. Margalit Rimona,ILX, Method of binding collagen recognizing substances to liposomes.
    상세보기
  22. Mirajkar Yelloji Rao K. ; Gaffar Abdul ; Stein Stefan,DEX ; Jahns Ekkehard,DEX ; Dieing Reinhold,DEX ; Sperling Karin,DEX, Oral composition exhibiting enhanced uptake by dental tissue of noncationic antibacterial agents.
    상세보기
  23. Canal Tiziana (Trieste ITX) Lovrecich Mara Lucia (Trieste ITX) Carli Fabio (Trieste ITX), Pharmaceutical compositions in the form of particles suitable for the controlled release of pharmacologically active sub.
    상세보기
  24. Canal Tiziana (Trieste ITX) Lovrecich Mara Lucia (Trieste ITX) Carli Fabio (Trieste ITX), Pharmaceutical compositions in the form of particles suitable for the controlled release of pharmacologically active sub.
    상세보기
  25. Santus Giancarlo (Milan ITX) Bottoni Giuseppe (Bergamo ITX) Sala Giovanni (Verona ITX), Pharmaceutical controlled-release composition with bioadhesive properties.
    상세보기
  26. Pikul Stanislaw ; McDow-Dunham Kelly Lynn ; De Biswanath ; Taiwo Yetunde Olabisi, Phosphinic acid amides as matrix metalloprotease inhibitors.
    상세보기
  27. Tanner Paul Robert ; Wagner Julie Ann ; Irwin Christopher, Photoprotective compositions.
    상세보기
  28. Adams Daniel J. (Cuyahoga Falls OH) Amjad Zahid (Brecksville OH) Lemma Solomon (Broadview Heights OH) Long ; II Carl J. (Elyria OH), Polycarboxylic acid thickeners, emulsifiers, and suspending aids having improved wettability characteristics.
    상세보기
  29. Hsu Chin C. (Avon Lake OH), Polycarboxylic acids with higher thickening capacity and better clarity.
    상세보기
  30. Amsden Brian G. (40 Fountainhead Road ; Apt. #1516 Downsview ; Ontario CAX M3J 2V1 ) Cheng Yu-Ling (1379 Glenburnie Road Mississauga ; Ontario CAX L5G 3C7 ), Polymer-based drug delivery system.
    상세보기
  31. Schlatzer ; Jr. Robert K. (Chagrin Falls OH), Polymerization of carboxylic acid monomers and alkyl acrylate esters in chlorofluoroethane.
    상세보기
  32. Berens Alan R. (6376 Elmcrest Dr. Hudson OH 44236) Huvard Gary S. (1085 Karen Dr. Akron OH 44313) Korsmeyer Richard W. (1257 Weathervane La. Akron OH 44313), Process for incorporating an additive into a polymer and product produced thereby.
    상세보기
  33. Tazi, Mohammed; Ardan, John J., Process for making copolymers of maleic anhydride and a C.sub.1 -C.sub.4 alkyl vinyl ether having a high specific viscosity.
    상세보기
  34. Engelhardt Friedrich (Frankfurt DEX) Schrod Manfred (Weiterstadt DEX) Ziegelmayer Manfred (Bischofsheim DEX) Hilbig Josef (Taunusstein DEX) Dnges Reinhard (Bad Soden DEX), Process for the preparation of a hydrogel which is largely free from monomers.
    상세보기
  35. Sojka Milan F. (Algonquin IL), Process for viscosifying water with carboxylic acid monomers polymerized in silicone solvents.
    상세보기
  36. Bai Jane Pei-Fan, Pulsatile drug delivery system.
    상세보기
  37. Schmidt Donald L. (Midland MI) Rose Gene D. (Midland MI) Miller Barbara A. (Midland MI), Reversible and irreversible water-based coatings.
    상세보기
  38. Tazi, Mohammed; Kwak, Yoon T.; Login, Robert B., Slurry polymerization of crosslinked maleic anhydride-alkyl vinyl ether copolymers in a solvent system comprising a carboxylic acid ester and a saturated hydrocarbon.
    상세보기
  39. Cohen Louis (Avon Lake OH), Solvent polymerization of carboxyl containing monomers.
    상세보기
  40. Chambers Douglas R. (Chesapeake VA) Chiang William G-J (Virginia Beach VA) Woodrum Guy T. (Chesapeake VA), Superabsorbent polymers and products therefrom.
    상세보기
  41. Schfer Doris (Arisdorf CHX) Schfer Rolf (Arisdorf CHX), Sustained release drug delivery system utilizing bioadhesive polymers.
    상세보기
  42. Floyd Christopher David,GBX ; Whittaker Mark,GBX, Synthesis of carboxylic and hydroxamic acid derivatives.
    상세보기
  43. Tzai, Mohammed; Plochocka, Krystyna; Kwak, Yoon T.; Rizzo, Thomas, Terpolymers of maleic anhydride, C.sub.1 -C.sub.5 alkyl vinyl ether and a C.sub.12 -C.sub.14 alpha-olefin, and crosslinked products thereof.
    상세보기
  44. M\Timkulu Thabiso (El Sobrante CA) Shaked Ze\ev (Berkeley CA) Hsu Richard (Union City CA 4), Topical bioadhesive ointment compositions and their use in wound healing.
    상세보기
  45. Venkateshwaran Srinivasan ; Ebert Charles D., Transdermal drug delivery matrix for coadministering estradiol and another steroid.
    상세보기
  46. Brown Peter Duncan,GB3 ; Bawden Lindsay Jayne,GB3 ; Miller Karen Margrete,GB3, Use of MMP inhibitors.
    상세보기
  47. Robinson Joseph R. (41 Chequamegon Rd. Madison WI 53719), Vaginal tissue moisturizing composition and method.
    상세보기
  48. Westerman Ira John (Strongsville OH), Water absorbent polymers comprising unsaturated carboxylic acid, acrylic ester containing alkyl group 10-30 carbon atoms.
    상세보기
  49. Huang Chor (Avon Lake OH) Schlatzer Robert K. (Chagrin Falls OH), Water thickening agents consisting of copolymers of crosslinked acrylic acids and esters.
    상세보기

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  1. Marchant, Nancy S., Bioadhesive hydrogels with functionalized degradable crosslinks.
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  2. Lee-Sepsick, Kathy; Azevedo, Max S., Contrast agent generation and injection system for sonographic imaging.
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  3. Lee-Sepsick, Kathy; Azevedo, Max S., Contrast agent injection system for sonographic imaging.
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  4. Guo, Jian-Hwa, Controlled release solid dosage carbamazepine formulations.
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  5. Taft, David; Bitler, Steven; Zheng, Qiang; Bell, Adam; Tzannis, Stelios, Delivery of drugs.
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  6. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Method and devices for conduit occlusion.
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  7. Taft, David; Tzannis, Stelios; Dai, Wei-Guo; Ottensmann, Sandra; Bitler, Steven; Zheng, Qiang; Bell, Adam, Method for formulating a controlled-release pharmaceutical formulation.
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  8. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
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  9. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
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  10. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
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  11. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
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  12. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  13. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  14. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  15. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  16. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  17. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
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  18. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    상세보기
  19. Lee-Sepsick, Kathy, Methods and devices for delivering to conduit.
    상세보기
  20. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
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  21. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
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  22. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
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  23. Lee-Sepsick, Kathy; Azevedo, Max S., Methods and devices for sonographic imaging.
    상세보기
  24. Lee-Sepsick, Kathy; Azevedo, Max S., Methods and devices for sonographic imaging.
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  25. Herr, John C.; Klibanov, Alexander L.; Eisenfrats, Kevin Simon, Methods for vas-occlusive contraception and reversal thereof.
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  26. Maitra, Prithwiraj; Zaidel, Lynette; Chopra, Suman K.; Pan, Guisheng; Prencipe, Michael; Ibrahim, Sayed, Oral care compositions with film forming polymers.
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  27. Nuria Carreras Perdiguer ES; Jose Alberto Vallet Mas ES; Gemma Torrella Cabello ES, Pharmaceutical compositions containing tobramycin and xanthan gum.
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  28. Taft, David; Tzannis, Stelios; Dai, Wei-Guo; Ottensmann, Sandra; Bitler, Steven; Zheng, Qiang; Bell, Adam, Polymer formulations for delivery of bioactive materials.
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  29. Tabata, Yasuhiko, Sustained release composition containing SDF-1.
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  30. Tabata, Yasuhiko, Sustained release composition containing SDF-1.
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  31. Taft, David D.; Bitler, Steven; Zheng, Qiang; Tzannis, Stelios; Bell, Adam; Dai, Wei-Guo; Ottensmann, Sandra N.; Balachander, Natarajan, Systems and methods for delivery of materials.
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  32. Rosenthal, Gary J.; Etter, Jeffrey B.; Rodell, Timothy C.; Schauer, Wren H.; Samaniego, Adrian, Treatment of mucositis.
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  33. Troha,Janice Mary; Abbas,Victoria Jean; Rosenthal,Gary Joseph; Schauer,Wren Henderson, Treatment of xerostomia.
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