초록 ▼

A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communication with a

A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communication with a detector, collecting the analyte in the collection reservoir, using the detector to detect the analyte in the collection reservoir, and, once the analyte has been detected, rendering the analyte undetectable by the detector. Also, apparatus for continual monitoring of a physiologic analyte in a subject includes a collection reservoir for receiving the analyte from the subject, the contents of the collection reservoir being in operative relationship with a detector that detects the analyte in the reservoir, and means for rendering the analyte, once detected, undetectable by the reservoir.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method for monitoring a physiologic analyte in a subject, comprising steps of:(a) contacting the subject with a collection reservoir such that the analyte can move from the subject into said collection reservoir, the contents of the collection reservoir being in opera

[ What is claimed is:] [1.]1. A method for monitoring a physiologic analyte in a subject, comprising steps of:(a) contacting the subject with a collection reservoir such that the analyte can move from the subject into said collection reservoir, the contents of the collection reservoir being in operative relationship with a detector,(b) collecting the analyte in the collection reservoir,(c) contacting the analyte with an enzyme that reacts with the analyte to produce a detectable chemical species, wherein the reaction of the analyte and the enzyme further results in conversion of the analyte to a reaction product that is not detected by the detector,(d) using the detector to detect the detectable chemical species in the collection reservoir, and once the detectable chemical species has been detected, rendering the detectable chemical species undetectable by the detector,repeating the steps (b), (c) and (d).