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Gene expression and evaluation system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G06F-017/30
출원번호 US-0122434 (1998-07-24)
발명자 / 주소
  • Balaban David J.
출원인 / 주소
  • Affymetrix Inc.
대리인 / 주소
    Townsend & Townsend & Crew LLP
인용정보 피인용 횟수 : 57  인용 특허 : 20

초록

An efficient and easy to use query system for a gene expression database. Using such a system, one can easily identify genes or expressed sequence tags whose expression correlates to particular tissue types. Various tissue types may correspond to different diseases, states of disease progression, di

대표청구항

[ What is claimed is:] [1.]1. In a computer system, a method for operating a database storing expression level information comprising:providing a database comprising files of expression level results for each of a plurality of genes or expressed sequence tags (EST) as measured in each of a plurality

이 특허에 인용된 특허 (20)

  1. Southern Edwin (Oxford GB2), Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays.
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  3. Ip Nancy Y. (Stamford CT) Baum Howard J. (Stony Point NY), Compositions and methods useful for genetic analysis.
  4. Hubbell Earl A. (Mt. View CA) Lipshutz Robert J. (Palo Alto CA) Morris Macdonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  5. Hubbell Earl A. (Mt. View CA) Morris MacDonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  6. Chee Mark S., Computer-aided visualization and analysis system for sequence evaluation.
  7. Shuber Anthony P., Direct sequence identification of mutations by cleavage- and ligation-associated mutation-specific sequencing.
  8. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
  9. Rothberg Jonathan Marc ; Deem Michael W. ; Simpson John W., Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing.
  10. Spinella Dominic G. ; Sajjadi Fereydoun G., Method for analyzing quantitative expression of genes.
  11. Sutcliffe J. Gregor ; Hasel Karl W., Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations.
  12. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of determining an ordered sequence of subfragments of a nucleic acid fragment by hybridization of oligonucleotide.
  13. Drmanac Radoje T. (Belgrade YUX) Crkvenjakov Radomir B. (Belgrade YUX), Method of sequencing by hybridization of oligonucleotide probes.
  14. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of sequencing by hybridization of oligonucleotide probes.
  15. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of sequencing of genoms by hybridization of oligonucleotide probes.
  16. Beattie Kenneth L., Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions.
  17. Funk Walter, Nucleic acid sequence of senescence asssociated gene.
  18. Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
  19. Rine Jasper ; Ashby Matthew, Systems for generating and analyzing stimulus-response output signal matrices.
  20. Bleck Gregory T. (Madison WI) Bremel Robert D. (Waunakee WI), Transgenic mice producing bovine a 상세보기

이 특허를 인용한 특허 (57)

  1. Szeto,Ernest, Analysis engine and work space manager for use with gene expression data.
  2. Shams,Soheil; Petrov,Anton, Apparatus, method, and computer program product for determining confidence measures and combined confidence measures for assessing the quality of microarrays.
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  4. Shams, Soheil, Automated DNA array image segmentation and analysis.
  5. Shams,Soheil, Automated DNA array image segmentation and analysis.
  6. Bugrim, Andrej; Webb, Craig P., Bioinformatics research and analysis system and methods associated therewith.
  7. Topaloglou, Thodoros; Kosky, Anthony, Biological data processing.
  8. Kincaid,Robert, Biotechnology information naming system.
  9. Huang, Wei; Fransen, Signe; Petropoulos, Christos; Toma, Jonathan; Whitcomb, Jeannette, Compositions and methods for determining whether a subject would benefit from co-receptor inhibitor therapy.
  10. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R., Computerized knowledge representation system with flexible user entry fields.
  11. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R., Constructing and maintaining a computerized knowledge representation system using fact templates.
  12. Gulati, Sandeep, Detecting events of interest using quantum resonance interferometry.
  13. Van Ooijen, Hendrik Jan; Van De Stolpe, Anja; Van Strijp, Dianne Arnoldina Margaretha Wilhelmina, Determination of TGF-β pathway activity using unique combination of target genes.
  14. Dowds, Carl A.; McIntyre, Jody C.; Erwin, Edgar E.; Wilson, Garret D.; Parmar, Pragna B.; Ohlson, Breck S.; Shippy, Richard D.; Cifuentes, Francisco J., Differential filtering of genetic data.
  15. Chen, Richard O.; Cho, Raymond J.; Felciano, Ramon M.; Holley, Bret; Patel, Viresh; Richards, Daniel R.; Selvarajan, Sushma; Steward, Keith; Schneider, Sara, Drug discovery methods.
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  18. Fu, Glenn K.; Jones, Keith W., Enzymatic methods for genotyping on arrays.
  19. Zhang, Ming, Gene expression browser for web-based search and visualization of characteristics of gene expression.
  20. Schermer,Mack J.; Stephan,Todd J., Interactive system for analyzing scatter plots.
  21. Mouritzen, Peter; Lomholt, Christian; Echwald, Søren Morgenthaler; Noerholm, Mikkel, Locked nucleic acid reagents for labelling nucleic acids.
  22. Shirazi, Mohsen, Manufacturing and processing polymer arrays.
  23. Haddon, William F.; Clarke, Nigel J., Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby.
  24. Haddon, William F.; Clarke, Nigel J., Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby.
  25. Bender, Kelly S.; Achenbach, Laurie, Metabolic primers for the detection of perchlorate-reducing bacteria and methods of use thereof.
  26. Balaban, David J.; Khurgin, Elina, Method and apparatus for providing an expression data mining database.
  27. Bassett, Jr., Douglas; Buskirk, Stewart; Bondarenko, Andrey, Method and system for analyzing biological response signal data.
  28. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R.; Norman, Philippa, Method and system for performing information extraction and quality control for a knowledgebase.
  29. Gulati, Sandeep, Method and system for signal detection in arrayed instrumentation based on quantum resonance interferometry.
  30. Gulati, Sandeep, Method and system using active signal processing for repeatable signal amplification in dynamic noise backgrounds.
  31. Hong, Kyeong Man, Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using SNP array.
  32. Gojobori,Takashi; Tanaka,Yuzuru; Okayama,Toshitsugu, Method, system, and program for use in displaying expression phenomenon in living matters.
  33. Gupta, Soumi; Fransen, Signe; Paxinos, Ellen; Parkin, Neil T., Methods and compositions for determining altered susceptibility of HIV-1 to anti-HIV drugs.
  34. Parkin, Neil T.; Coakley, Eoin, Methods and compositions for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors.
  35. McLoughlin,Kevin; Collin,Francois; Markowitz,Victor M.; Topaloglou,Thodoros; Athanasopoulos,Alexandros, Methods and systems for efficient comparison, identification, processing, and importing of gene expression data.
  36. Parkin, Neil T.; Coakley, Eoin, Methods for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors.
  37. Huang, Wei, Methods for determining resistance or susceptibility to HIV entry inhibitors.
  38. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R., Methods for the construction and maintenance of a knowledge representation system.
  39. Dickinson, Todd; Coblentz, Kenneth D.; Carlson, Edward, Methods of detecting targets on an array.
  40. O'Donnell, Jude; Bylesjo, Max; Patterson, Fionnuala; Deharo, Steve; Hill, Laura A.; Keating, Katherine E.; Davison, Timothy; Proutski, Vitali; Harkin, Denis Paul; Kennedy, Richard; Goffard, Nicolas, Molecular diagnostic test for cancer.
  41. O'Donnell, Jude; Bylesjo, Max; Patterson, Fionnuala; Deharo, Steve; Hill, Laura A.; Keating, Katherine E.; Davison, Timothy; Proutski, Vitali; Harkin, Denis Paul; Kennedy, Richard; Goffard, Nicolas, Molecular diagnostic test for cancer.
  42. Qu,Kunbin; Lin,Nan; Lu,Yanmei; Payan,Donald G., Multidimensional biodata integration and relationship inference.
  43. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian Bing; Shen, Min Jui Richard, Multiplex nucleic acid reactions.
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  46. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian-Bing; Shen, Min-Jui Richard, Multiplex nucleic acid reactions.
  47. Shen, Min-Jui Richard; Oliphant, Arnold; Butler, Scott L.; Stuelpnagel, John R.; Chee, Mark S.; Kuhn, Kenneth M.; Fan, Jian-Bing, Multiplex nucleic acid reactions.
  48. Fan, Jian-Bing, Multiplexed methylation detection methods.
  49. Engelhardt,Dean; Rabbani,Elazar; Kline,Stanley; Stavrianopoulos,Janes G.; Kirtikar,Dollie, Oligo-or polynucleotides comprising phosphate-moiety labeled nucleotides.
  50. Clarke, Michael F.; Quake, Stephen R.; Dalerba, Piero D.; Liu, Huiping; Leyrat, Anne; Kalisky, Tomer; Diehn, Maximilian; Wang, Jianbin, Single cell gene expression for diagnosis, prognosis and identification of drug targets.
  51. Sorace, James M.; Canfield, Gerald, Software method for the conversion, storage and querying of the data of cellular biological assays on the basis of experimental design.
  52. Shams,Soheil; Park,James Darrell; Zhou,Yi Xiong, System and method for automatically processing microarrays.
  53. Gulati,Sandeep, System and method for characterizing microarray output data.
  54. Gulati,Sandeep, Technique for extracting arrayed data.
  55. Gulati, Sandeep, Technique for quantiating biological markers using quantum resonance interferometry.
  56. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R.; Norman, Philippa, Techniques for facilitating information acquisition and storage.
  57. Cho, Raymond J.; Chen, Richard O.; Felciano, Ramon M.; Richards, Daniel R.; Norman, Philippa, Techniques for facilitating information acquisition and storage.
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