초록 ▼

An injectable depot gel composition containing a polymer, a solvent that can dissolve the polymer and thereby form a viscous gel, a beneficial agent; and an emulsifying agent in the form of a dispersed droplet phase in the viscous gel. The injectable depot gel composition can be prepared by mixing t

An injectable depot gel composition containing a polymer, a solvent that can dissolve the polymer and thereby form a viscous gel, a beneficial agent; and an emulsifying agent in the form of a dispersed droplet phase in the viscous gel. The injectable depot gel composition can be prepared by mixing the polymer and the solvent so that the solvent dissolves the polymer and forms a viscous gel. The beneficial agent is dissolved or dispersed in the viscous gel and the emulsifying agent is mixed with the beneficial agent containing viscous gel. The emulsifying agent forms a dispersed droplet phase in the viscous gel to provide the injectable depot gel composition. The injectable depot gel composition can deliver a beneficial agent to a human or animal with a desired release profile.

대표청구항 ▼

[ We claim:] [1.]1. An injectable depot gel composition comprising:a continuous, viscous gel phase comprisinga biocompatible polymer andan organic solvent that dissolves the biocompatible polymer and forms a viscous gel;a beneficial agent; and a separate, droplet phase dispersed in the viscous gel p

[ We claim:] [1.]1. An injectable depot gel composition comprising:a continuous, viscous gel phase comprisinga biocompatible polymer andan organic solvent that dissolves the biocompatible polymer and forms a viscous gel;a beneficial agent; and a separate, droplet phase dispersed in the viscous gel phase comprisingan emulsifying agent, whereby the depot gel composition is thixotropic.