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Recombinant papillomavirus vaccine and method for production and treatment 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/00
  • A61K-039/12
  • C07H-021/04
  • C07H-014/00
출원번호 US-0485885 (2000-02-18)
우선권정보 GB-0017953 (1997-08-22)
국제출원번호 PCT/EP98/05285 (1998-08-17)
§371/§102 date 20000218 (20000218)
국제공개번호 WO99/10375 (1999-03-04)
발명자 / 주소
  • Claudine Bruck BE
  • Teresa Cabezon Silva BE
  • Anne-Marie Eva Fernande Delisse BE
  • Catherine Marie Ghislaine Gerard BE
  • Angela Lombardo-Bencheikh BE
출원인 / 주소
  • SmithKline Beecham Biologicals, S.A. BE
대리인 / 주소
    William R. Majarian
인용정보 피인용 횟수 : 26  인용 특허 : 3

초록

The present invention relates to fusions proteins, comprising a protein or part of a protein that provides T helper epitopes and an antigen from a human-papilloma virus. In particular the invention relates to fusion proteins comprising an E6 or E7 protein from HPV strain 16 or 18 linked to protein D

대표청구항

1. A fusion protein comprising Human papilloma virus antigen selected from the group consisting of fusion proteins E6, E7 and E6E7, linked to protein D or derivative therof from Haemophilius influenzae B, wherein the derivative thereof comprises approximately the first N-terminal 100 amino acids of

이 특허에 인용된 특허 (3)

  1. Au-Young Janice ; Hawkins Phillip R. ; Hillman Jennifer L., Human hyaluronidase.
  2. Cheever Martin A. ; Disis Mary L., Methods for eliciting or enhancing reactivity to HER-2/neu protein.
  3. Segal Andrew H., Vaccine compositions and methods of modulating immune responses.

이 특허를 인용한 특허 (26)

  1. Garcon, Nathalie, Adjuvant systems and vaccines.
  2. Harris, Everette; Gendler, Jeffrey, Apparatus and systems for upgrading heavy oil using catalytic hydrocracking and thermal coking.
  3. Sun, Shujun; Gallo, Christopher, Arginine derivative wash in protein purification using affinity chromatography.
  4. Sun, Shujun, Arginine wash in protein purification using affinity chromatography.
  5. Sung, Young Chul; Seo, Sang Hwan; Suh, You Suk, Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer.
  6. Sung, Young Chul; Seo, Sang Hwan; Suh, You Suk, Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer.
  7. Chen, Michael C.; Chiou, Chuang Jiun; Li, Zhongming; Chen, Dong Sheng, Compositions and methods for treating or preventing pneumococcal infection.
  8. Chen,Michael C.; Chiou,Chuang Jiun; Li,Zhongming; Chen,Dong Sheng, Compositions and methods for treating or preventing pneumococcal infection.
  9. Weiner, David B.; Yan, Jian, HIV consensus envelope sequences and methods for using the same.
  10. Weiner, David B; Yan, Jian; Laddy, Dominick, HIV consensus envelope sequences and methods for using the same.
  11. Weiner, David B; Yan, Jian, HPV vaccines and methods for using the same.
  12. Ott, Gary S.; O'Hagan, Derek; Singh, Manmohan, Immunological adjuvant compositions.
  13. Ott, Gary S.; Singh, Manmohan; O'Hagan, Derek, Immunological adjuvant compositions.
  14. Lott, Roger K.; Lee, Lap Keung, Method for upgrading ebullated bed reactor and upgraded ebullated bed reactor.
  15. Chesnut, Jonathan D.; Carrino, John; Leong, Louis; Madden, Knut; Gleeson, Martin; Fan, James; Brasch, Michael; Cheo, David; Hartley, James L.; Byrd, Devon R.; Temple, Gray F., Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites.
  16. Chesnut, Jonathan; Carrino, John; Leong, Louis; Madden, Knut; Gleeson, Martin; Fan, James; Brasch, Michael; Cheo, David; Hartley, James; Byrd, Devon; Temple, Gary, Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites.
  17. Chesnut, Jonathan; Carrino, John; Leong, Louis; Madden, Knut; Gleeson, Martin; Fan, James; Brasch, Michael; Cheo, David; Hartley, James; Byrd, Devon; Temple, Gary, Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites.
  18. Harris, Everette; Gendler, Jeffrey, Methods and systems for upgrading heavy oil using catalytic hydrocracking and thermal coking.
  19. Chang, Yu-Hwa, Methods for increasing catalyst concentration in heavy oil and/or coal resid hydrocracker.
  20. Chesnut, Jon; Leong, Louis, Nucleic acid molecules containing recombination sites and methods of using the same.
  21. Chesnut, Jonathan; Leong, Louis, Nucleic acid molecules containing recombination sites and methods of using the same.
  22. Lee, John H.; Vermeer, Daniel W., Polynucleotides for treating oncogenic viral polypeptide positive tumors.
  23. Lee, John H.; Vermeer, Daniel W., Polynucleotides for treating oncogenic viral polypeptide positive tumors.
  24. Lott, Roger K.; Lee, Lap-Keung, Systems and methods for hydroprocessing heavy oil.
  25. Lott, Roger K.; Lee, Lap Keung, Systems for hydroprocessing heavy oil.
  26. Weiner, David B.; Yan, Jian, hTERT sequences and methods for using the same.
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