초록 ▼

A microsampling device useable in a multiple channel high throughput purification system for purifying a plurality of samples, preferably four or more samples from a chemical library. One aspect of the invention provides a microsampling device for use in the high throughput fluid system. The microsa

A microsampling device useable in a multiple channel high throughput purification system for purifying a plurality of samples, preferably four or more samples from a chemical library. One aspect of the invention provides a microsampling device for use in the high throughput fluid system. The microsampling device includes a body with a sample flow inlet, a sample flow outlet, and a sample passageway there between. The sample flow inlet and outlet are positionable for fluid communication with the sample flow path of the fluid system. The body has a carrier flow inlet and a carrier flow outlet positioned before fluid communication with the carrier fluid flow path of the high throughput fluid system. The carrier flow inlet and carrier flow outlet are axially misaligned. A stem is movably disposed in the body and in fluid communication with the sample passageway. The stem is moveable between first and second positions. The stem has a fluid bypass fluidly interconnecting the carrier flow inlet and outlet when the stem is in the first position to allow a selected carrier fluid to flow through the valve body to, as an example, a mass spectrometer or other analyzer.

대표청구항 ▼

1. A microsampling device for use in a high throughput fluid system, the fluid system having a flow channel with a sample flow path, a carrier flow path, and a fluid receiving member in fluid communication with the sample and carrier flow paths, comprising:a body having a sample flow inlet, a sample

1. A microsampling device for use in a high throughput fluid system, the fluid system having a flow channel with a sample flow path, a carrier flow path, and a fluid receiving member in fluid communication with the sample and carrier flow paths, comprising:a body having a sample flow inlet, a sample flow outlet, and sample passageway therebetween, the sample flow inlet and outlet being positionable for fluid communication with the sample flow path, the body having a carrier flow inlet and carrier flow outlet and being positionable for fluid communication with the carrier fluid flow path, the carrier flow inlet and carrier flow outlet being axially misaligned; a stem movably disposed in the body and in fluid communication with the sample passageway, the stem being moveable between first and second positions, the stem having a fluid bypass fluidly interconnecting the carrier flow inlet and outlet when the stem is in the first position to allow a selected carrier fluid to flow through the valve body, the stem blocking the sample flow in the sample passageway flowing to the carrier flow outlet when in the first position, the fluid bypass in fluid communication with the sample passageway and the carrier flow outlet when in the second position to allow a selected sampling of the sample flow to flow to the carrier flow outlet; and an actuator coupled to the stem and being activatable to move the stem substantially immediately between the first and second positions.